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• W2783705456 abstract "The skull base is made of flat bones that separate the intracranial compartment from the extracranial head and neck. Owing to this unique location, it can be affected both by intrinsic lesions originating from the bony elements of the skull base and by lesions originating outside the skull base proper or from trapped embryonic remnants. This chapter specifically focuses on the imaging techniques, developmental anomalies, skull base lesions originating from embryonic remnants, skull base infection, and other diffuse skull base lesions. Diagnostic imaging may require the use of different techniques, most often CT, MRI, bone scintigraphy, and PET-CT and is crucial in patient’s management, as the skull base is hidden from clinical inspection. Awareness of anatomic variants is crucial in surgical planning and to avoid potential confusion with skull base lesions. Moreover, radiologists should also be familiar with embryonic abnormalities affecting the skull base. Often, their particular location and other associated imaging features can be diagnostic. Proximity with sinus cavities (sinonasal and otomastoid) and with the nasopharynx makes the skull base prone to spread of infectious processes when appropriate treatment is delayed. Skull base osteomyelitis from bacterial or fungal agents remains a diagnostic challenge, particularly in the absence of relevant clinical data, and requires a high degree of suspicion. Diffuse bone lesions affecting the skull base result from defects of endochondral ossification, which may also affect the remaining skeleton. Overall, diagnostic imaging of these conditions is similar to that of bone lesions outside the skull base and the same rules for differential diagnosis apply." @default.
• W2783705456 created "2018-01-26" @default.
• W2783705456 creator A5008583154 @default.
• W2783705456 date "2018-01-01" @default.
• W2783705456 modified "2023-09-28" @default.
• W2783705456 title "Skull Base Bone Lesions I" @default.
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