FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783718177> ?p ?o ?g. }

• W2783718177 endingPage "1133.e6" @default.
• W2783718177 startingPage "1133.e1" @default.
• W2783718177 abstract "Purpose To determine the factors affecting outcomes in surgically salvaged, locoregionally recurrent squamous cell carcinoma of the tongue (SCCT). Materials and Methods In a retrospective cohort of patients who underwent successful salvage of locoregionally recurrent SCCT, we performed this observational analytical study to determine survival and its determinants. Details extracted from our database were patient characteristics (age, gender, tobacco use), treatment characteristics, and characteristics of recurrent disease (stage and adverse pathologic features [APFs] such as grade, perineural invasion, and lymphovascular invasion). Overall survival (OS) curves were plotted using the Kaplan-Meier method. A Cox proportional hazards model was used to determine the impact of patient, disease, and treatment characteristics on OS. Results Of 52 patients with locoregional recurrences of surgically treated SCCT, 25 (48.1%) underwent surgical salvage with curative intent. The median overall OS for this cohort was 26 months. Factors predictive of worse OS were previous adjuvant therapy (P = .016) and increasing APFs in recurrent tumor histology (P = .008). Lymphovascular invasion in recurrent tumor histology and patients with a disease-free interval of less than 6 months showed worse survival (P = .008 and P = .058, respectively). Conclusions Among patients with locoregional recurrence, the number who are eligible for curative-intent surgical salvage is small. Those who received previous adjuvant therapy and those with increasing APFs in recurrent tumors had poor outcomes despite attempts at surgical salvage, particularly patients with early recurrence. To determine the factors affecting outcomes in surgically salvaged, locoregionally recurrent squamous cell carcinoma of the tongue (SCCT). In a retrospective cohort of patients who underwent successful salvage of locoregionally recurrent SCCT, we performed this observational analytical study to determine survival and its determinants. Details extracted from our database were patient characteristics (age, gender, tobacco use), treatment characteristics, and characteristics of recurrent disease (stage and adverse pathologic features [APFs] such as grade, perineural invasion, and lymphovascular invasion). Overall survival (OS) curves were plotted using the Kaplan-Meier method. A Cox proportional hazards model was used to determine the impact of patient, disease, and treatment characteristics on OS. Of 52 patients with locoregional recurrences of surgically treated SCCT, 25 (48.1%) underwent surgical salvage with curative intent. The median overall OS for this cohort was 26 months. Factors predictive of worse OS were previous adjuvant therapy (P = .016) and increasing APFs in recurrent tumor histology (P = .008). Lymphovascular invasion in recurrent tumor histology and patients with a disease-free interval of less than 6 months showed worse survival (P = .008 and P = .058, respectively). Among patients with locoregional recurrence, the number who are eligible for curative-intent surgical salvage is small. Those who received previous adjuvant therapy and those with increasing APFs in recurrent tumors had poor outcomes despite attempts at surgical salvage, particularly patients with early recurrence." @default.
• W2783718177 created "2018-01-26" @default.
• W2783718177 creator A5007096166 @default.
• W2783718177 creator A5018123832 @default.
• W2783718177 creator A5019104326 @default.
• W2783718177 creator A5027565185 @default.
• W2783718177 creator A5052951530 @default.
• W2783718177 creator A5059333681 @default.
• W2783718177 creator A5087858095 @default.
• W2783718177 date "2018-05-01" @default.
• W2783718177 modified "2023-09-27" @default.
• W2783718177 title "Factors Affecting Survival in Surgically Salvaged Locoregional Recurrences of Squamous Cell Carcinoma of the Tongue" @default.
• W2783718177 cites W1509422232 @default.
• W2783718177 cites W1965026478 @default.
• W2783718177 cites W1977072512 @default.
• W2783718177 cites W2015925731 @default.
• W2783718177 cites W2025712277 @default.
• W2783718177 cites W2027999349 @default.
• W2783718177 cites W2033290447 @default.
• W2783718177 cites W2055532630 @default.
• W2783718177 cites W2062831861 @default.
• W2783718177 cites W2065900444 @default.
• W2783718177 cites W2066881118 @default.
• W2783718177 cites W2067551303 @default.
• W2783718177 cites W2069355079 @default.
• W2783718177 cites W2075166004 @default.
• W2783718177 cites W2077748641 @default.
• W2783718177 cites W2103065467 @default.
• W2783718177 cites W2115611141 @default.
• W2783718177 cites W2127857200 @default.
• W2783718177 cites W2143161736 @default.
• W2783718177 cites W2163802618 @default.
• W2783718177 cites W2168115954 @default.
• W2783718177 cites W2168943926 @default.
• W2783718177 cites W2169660224 @default.
• W2783718177 cites W2508805566 @default.
• W2783718177 doi "https://doi.org/10.1016/j.joms.2017.12.029" @default.
• W2783718177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29406254" @default.
• W2783718177 hasPublicationYear "2018" @default.
• W2783718177 type Work @default.
• W2783718177 sameAs 2783718177 @default.
• W2783718177 citedByCount "11" @default.
• W2783718177 countsByYear W27837181772019 @default.
• W2783718177 countsByYear W27837181772020 @default.
• W2783718177 countsByYear W27837181772021 @default.
• W2783718177 countsByYear W27837181772022 @default.
• W2783718177 countsByYear W27837181772023 @default.
• W2783718177 crossrefType "journal-article" @default.
• W2783718177 hasAuthorship W2783718177A5007096166 @default.
• W2783718177 hasAuthorship W2783718177A5018123832 @default.
• W2783718177 hasAuthorship W2783718177A5019104326 @default.
• W2783718177 hasAuthorship W2783718177A5027565185 @default.
• W2783718177 hasAuthorship W2783718177A5052951530 @default.
• W2783718177 hasAuthorship W2783718177A5059333681 @default.
• W2783718177 hasAuthorship W2783718177A5087858095 @default.
• W2783718177 hasConcept C121608353 @default.
• W2783718177 hasConcept C126322002 @default.
• W2783718177 hasConcept C141071460 @default.
• W2783718177 hasConcept C142724271 @default.
• W2783718177 hasConcept C143998085 @default.
• W2783718177 hasConcept C146357865 @default.
• W2783718177 hasConcept C151730666 @default.
• W2783718177 hasConcept C167135981 @default.
• W2783718177 hasConcept C2776694085 @default.
• W2783718177 hasConcept C2777154038 @default.
• W2783718177 hasConcept C2777546739 @default.
• W2783718177 hasConcept C2777982462 @default.
• W2783718177 hasConcept C2778740770 @default.
• W2783718177 hasConcept C2779013556 @default.
• W2783718177 hasConcept C2779744641 @default.
• W2783718177 hasConcept C2780775027 @default.
• W2783718177 hasConcept C2909392909 @default.
• W2783718177 hasConcept C50382708 @default.
• W2783718177 hasConcept C71924100 @default.
• W2783718177 hasConcept C72563966 @default.
• W2783718177 hasConcept C86803240 @default.
• W2783718177 hasConceptScore W2783718177C121608353 @default.
• W2783718177 hasConceptScore W2783718177C126322002 @default.
• W2783718177 hasConceptScore W2783718177C141071460 @default.
• W2783718177 hasConceptScore W2783718177C142724271 @default.
• W2783718177 hasConceptScore W2783718177C143998085 @default.
• W2783718177 hasConceptScore W2783718177C146357865 @default.
• W2783718177 hasConceptScore W2783718177C151730666 @default.
• W2783718177 hasConceptScore W2783718177C167135981 @default.
• W2783718177 hasConceptScore W2783718177C2776694085 @default.
• W2783718177 hasConceptScore W2783718177C2777154038 @default.
• W2783718177 hasConceptScore W2783718177C2777546739 @default.
• W2783718177 hasConceptScore W2783718177C2777982462 @default.
• W2783718177 hasConceptScore W2783718177C2778740770 @default.
• W2783718177 hasConceptScore W2783718177C2779013556 @default.
• W2783718177 hasConceptScore W2783718177C2779744641 @default.
• W2783718177 hasConceptScore W2783718177C2780775027 @default.
• W2783718177 hasConceptScore W2783718177C2909392909 @default.
• W2783718177 hasConceptScore W2783718177C50382708 @default.
• W2783718177 hasConceptScore W2783718177C71924100 @default.
• W2783718177 hasConceptScore W2783718177C72563966 @default.
• W2783718177 hasConceptScore W2783718177C86803240 @default.
• W2783718177 hasIssue "5" @default.

• next