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- W2783803118 abstract "Cinnamon (Cinnamomum zeylanicum, Lauraceae) is a food additive greatly used for its taste. However, recently this medicinal plant has been brought to attention due to its medical effects. Cinnamon has constituents such as cinnamaldehyde and cinnamic acid that offers some health benefits including antioxidant and free-radical scavenging properties, lowering of blood glucose, anti-cholesterolemic, analgesic, antimicrobial, anti-inflammatory, anti-yeast, anti-secretagogue, and anti-gastric ulcer effects. This review summarizes various in vitro and animal studies on the protective effects of cinnamon against natural and chemical toxins. These studies consider the antidotal and/or protective effects of cinnamon and its major constituents against natural toxins and chemical-induced toxicities. It has been mentioned that cinnamon and its main constituents can ameliorate the toxicity of chemical toxins in liver, kidney, blood, brain, embryo, reproductive system, heart, spleen in part through antioxidant effect, radical scavenging, reducing lipid peroxidation, anti-inflammatory, fungistatic and fungicidal activities, modulation of CK-MB, LDH, TNF-α, IL-6, mitogen-activated protein kinase (MAPK), and nuclear factor-ĸB (NF-ĸB) signaling pathways." @default.
- W2783803118 created "2018-01-26" @default.
- W2783803118 creator A5015123190 @default.
- W2783803118 creator A5029234555 @default.
- W2783803118 creator A5031619408 @default.
- W2783803118 date "2018-01-10" @default.
- W2783803118 modified "2023-10-02" @default.
- W2783803118 title "Cinnamon (<i>Cinnamomum zeylanicum</i>) as an antidote or a protective agent against natural or chemical toxicities: a review" @default.
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- W2783803118 doi "https://doi.org/10.1080/01480545.2017.1417995" @default.
- W2783803118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29319361" @default.
- W2783803118 hasPublicationYear "2018" @default.
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