Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783805474> ?p ?o ?g. }
- W2783805474 endingPage "39" @default.
- W2783805474 startingPage "33" @default.
- W2783805474 abstract "Trinitrobenzensulfonic acid (TNBS) is commonly used to induce an experimental inflammatory bowel disease (IBD) model. Oxidative stress and inflammation have been proposed as mechanisms underlying the pathophysiology of IBD. Aronia melanocarpa fruit juice (AMFJ) is extremely rich in polyphenolic substances, mainly proanthocyanidins, flavonoids and phenolic acids. The aim of this study was to evaluate the effect of AMFJ in a rat TNBSinduced colitis model and to compare the effect of the juice with that of sulfasalazine. Colitis was induced by TNBS in male Wistar rats. After the induction of colitis, AMFJ at three doses (2.5, 5 and 10 mL/kg) and sulfasalazine (400 mg/kg) were administered orally till the 14th experimental day. Severity of colitis was assessed by macroscopic and histopathological criteria. Oxidative stress was evaluated by the concentration of thiobarbituric acid reactive substances (TBARS). TNBS caused severe colonic damage. AMFJ dose-dependently ameliorated TNBS-induced colitis. It improved the macroscopic and microscopic signs of colitis, and prevented the increase of colonic TBARS concentrations. Regarding different indices, the effect of AMFJ was comparable or even higher than that of sulfasalazine. In conclusion, the ameliorative effects of AMFJ in the experimental TNBSinduced colitis might be the result of its potent antioxidant and antiinflammatory properties." @default.
- W2783805474 created "2018-01-26" @default.
- W2783805474 creator A5014151001 @default.
- W2783805474 creator A5017184938 @default.
- W2783805474 creator A5050312179 @default.
- W2783805474 creator A5052793342 @default.
- W2783805474 date "2018-03-01" @default.
- W2783805474 modified "2023-10-12" @default.
- W2783805474 title "Aronia melanocarpa fruit juice ameliorates the symptoms of inflammatory bowel disease in TNBS-induced colitis in rats" @default.
- W2783805474 cites W1550488867 @default.
- W2783805474 cites W1938907407 @default.
- W2783805474 cites W1966010545 @default.
- W2783805474 cites W1970247674 @default.
- W2783805474 cites W1971570374 @default.
- W2783805474 cites W1972053214 @default.
- W2783805474 cites W1983310681 @default.
- W2783805474 cites W1992557371 @default.
- W2783805474 cites W1998553163 @default.
- W2783805474 cites W2001665658 @default.
- W2783805474 cites W2007277298 @default.
- W2783805474 cites W2011521753 @default.
- W2783805474 cites W2017899449 @default.
- W2783805474 cites W2020444219 @default.
- W2783805474 cites W2030619287 @default.
- W2783805474 cites W2042612606 @default.
- W2783805474 cites W2052259257 @default.
- W2783805474 cites W2056988655 @default.
- W2783805474 cites W2058030003 @default.
- W2783805474 cites W2065076024 @default.
- W2783805474 cites W2069490622 @default.
- W2783805474 cites W2078629562 @default.
- W2783805474 cites W2084860737 @default.
- W2783805474 cites W2093190113 @default.
- W2783805474 cites W2095484290 @default.
- W2783805474 cites W2095516254 @default.
- W2783805474 cites W2098197882 @default.
- W2783805474 cites W2108302236 @default.
- W2783805474 cites W2111619432 @default.
- W2783805474 cites W2113855055 @default.
- W2783805474 cites W2114004260 @default.
- W2783805474 cites W2138555287 @default.
- W2783805474 cites W2140611448 @default.
- W2783805474 cites W2146711122 @default.
- W2783805474 cites W2152119969 @default.
- W2783805474 cites W2188406439 @default.
- W2783805474 cites W2725093142 @default.
- W2783805474 cites W4254679467 @default.
- W2783805474 doi "https://doi.org/10.1016/j.fct.2018.01.011" @default.
- W2783805474 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29331733" @default.
- W2783805474 hasPublicationYear "2018" @default.
- W2783805474 type Work @default.
- W2783805474 sameAs 2783805474 @default.
- W2783805474 citedByCount "29" @default.
- W2783805474 countsByYear W27838054742018 @default.
- W2783805474 countsByYear W27838054742019 @default.
- W2783805474 countsByYear W27838054742020 @default.
- W2783805474 countsByYear W27838054742021 @default.
- W2783805474 countsByYear W27838054742022 @default.
- W2783805474 countsByYear W27838054742023 @default.
- W2783805474 crossrefType "journal-article" @default.
- W2783805474 hasAuthorship W2783805474A5014151001 @default.
- W2783805474 hasAuthorship W2783805474A5017184938 @default.
- W2783805474 hasAuthorship W2783805474A5050312179 @default.
- W2783805474 hasAuthorship W2783805474A5052793342 @default.
- W2783805474 hasConcept C126322002 @default.
- W2783805474 hasConcept C185592680 @default.
- W2783805474 hasConcept C2775862500 @default.
- W2783805474 hasConcept C2776151105 @default.
- W2783805474 hasConcept C2777352226 @default.
- W2783805474 hasConcept C2777504301 @default.
- W2783805474 hasConcept C2778004101 @default.
- W2783805474 hasConcept C2778260677 @default.
- W2783805474 hasConcept C2779134260 @default.
- W2783805474 hasConcept C2779383735 @default.
- W2783805474 hasConcept C2780479503 @default.
- W2783805474 hasConcept C2780829032 @default.
- W2783805474 hasConcept C55493867 @default.
- W2783805474 hasConcept C71924100 @default.
- W2783805474 hasConcept C90924648 @default.
- W2783805474 hasConcept C98274493 @default.
- W2783805474 hasConceptScore W2783805474C126322002 @default.
- W2783805474 hasConceptScore W2783805474C185592680 @default.
- W2783805474 hasConceptScore W2783805474C2775862500 @default.
- W2783805474 hasConceptScore W2783805474C2776151105 @default.
- W2783805474 hasConceptScore W2783805474C2777352226 @default.
- W2783805474 hasConceptScore W2783805474C2777504301 @default.
- W2783805474 hasConceptScore W2783805474C2778004101 @default.
- W2783805474 hasConceptScore W2783805474C2778260677 @default.
- W2783805474 hasConceptScore W2783805474C2779134260 @default.
- W2783805474 hasConceptScore W2783805474C2779383735 @default.
- W2783805474 hasConceptScore W2783805474C2780479503 @default.
- W2783805474 hasConceptScore W2783805474C2780829032 @default.
- W2783805474 hasConceptScore W2783805474C55493867 @default.
- W2783805474 hasConceptScore W2783805474C71924100 @default.
- W2783805474 hasConceptScore W2783805474C90924648 @default.
- W2783805474 hasConceptScore W2783805474C98274493 @default.
- W2783805474 hasFunder F4320321843 @default.
- W2783805474 hasLocation W27838054741 @default.