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- W2783806690 abstract "Measurement of coagulation assay is pivotal all across in different specialties in field of medicine. We compared prothrombin time, activated prothrombin time and fibrinogen from fresh blood samples drawn into glass vs. plastic tubes. There was a recent recall of glass tubes nationwide from a leading manufacture. This type of situation imposes difficult scenario and put labs in a dilemma whether to use plastic tubes in place of glass tubes. Also the literature is extremely sparse in reference to the use of plastic tubes and shows inconsistence results. Hence, there is a need for further studies. To handle this scenario of the recall, the quality assurance project was performed at CMC Philadelphia VA Medical Center. We collected 65 venous blood samples into 4.5 mL glass tubes and 2.7 mL plastic tubes from mix population patients with and without anticoagulant therapy. After centrifugation we used Diagnostic Stago instrument with Stago reagents for this testing. Mean and standard deviation (SD) were used to verify the adequacy of the analytic ranges in the study and to summarize results. In our results, there was no statistically significance difference observed in prothrombin time, activated partial thromboplastin time, and fibrinogen results. We used Bland-Altman plot for determination of results comparison. Bland-Altman plot shows good correlation between two methods, and their regression shows excellent correlation of r values between 0.98 and 1.00. There is no indication of bias between the methods. Our study shows that the plastic tubes can be safely and successfully used for the coagulation studies in place of glass tubes." @default.
- W2783806690 created "2018-01-26" @default.
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- W2783806690 date "2018-01-01" @default.
- W2783806690 modified "2023-09-26" @default.
- W2783806690 title "72 Evaluation (Correlation/Validation) of 0.109M BD Vacutainer Plus Plastic (2.7 mL) and 0.105M BD Vacutainer Glass Sodium Citrate Tubes (4.5 mL) for PT, APTT, and Fibrinogen Using Diagnostic Stago STA" @default.
- W2783806690 doi "https://doi.org/10.1093/ajcp/aqx116.071" @default.
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