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- W2783807566 abstract "The development of therapeutic options to promote hepatic regeneration following severe liver injury is essential. While humoral factors have been reported as mechanisms of liver regeneration, the contributions of interorgan communication to liver regeneration have not been reported. In this study, we examined the effect of a neural relay on liver regeneration via activation of serotonin release from the gastrointestinal (GI) tract. Our results demonstrated that the afferent visceral nerve from the liver activates the efferent vagus nerve from the brain, leading to activation of serotonin release from the GI tract and contributing to liver regeneration. While it is difficult to apply these results directly to human health, we believe that this study may represent a step toward developing essential therapeutics to promote liver regeneration." @default.
- W2783807566 created "2018-01-26" @default.
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- W2783807566 date "2018-01-31" @default.
- W2783807566 modified "2023-10-06" @default.
- W2783807566 title "Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract" @default.
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- W2783807566 doi "https://doi.org/10.1002/2211-5463.12382" @default.
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