Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783994285> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2783994285 abstract "Background and ObjectiveAerobic exercise has a strong effect on skeletal muscle metabolism, in both males and females of all ages. However, the effect of a single bout of aerobic exercise on the regulation of protein balance remains unknown. In the present study, we investigated the effect of a single bout of treadmill-based exercise on the levels of various protein synthesis-related eukaryotic proteins (initiation factor 2a, eukaryotic initiation factor 4E, eukaryotic initiation factor 4E-binding protein 1, and eukaryotic elongation factor 2), breakdown-related proteins (microtubule-associated protein 1 light chain 3 alpha (LC3), autophagy-related 7, and muscle RING-finger protein 1 (MuRF1)), and polyubiquitination in 3-month-old male ICR mice.Material and MethodsTwenty-four male mice were randomized into four time-point groups; each group of mice was run on a rodent treadmill for 10 min at 10 m/min at a slope of 5° between 7:00 p.m. and 8:00 p.m. for 2 days during the adaptation period. On the third day, exercise was performed for 50 min at a speed of 12.3 m/min; the control mice did not perform any exercise. Gastrocnemius muscles were collected immediately after the mice were sacrificed by cervical dislocation at 0, 3, 6, or 12 hours post-exercise.ResultsLevels of synthesis-related proteins were significantly reduced at 3 and 6 hours into the recovery period, whereas levels of breakdown-related proteins, including that of the autophagy marker LC3, increased immediately after exercise but not during the recovery period. MuRF1 level was determined in the gastrocnemius muscle to identify the factors involved in this increase. We found that increased MuRF1 levels were associated with an increase in polyubiquitination during the recovery period.ConclusionOur results suggest a potential role of optimal time points in muscle protein metabolism during recovery from a single bout of treadmill exercise." @default.
- W2783994285 created "2018-01-26" @default.
- W2783994285 creator A5044297403 @default.
- W2783994285 creator A5074329506 @default.
- W2783994285 date "2018-01-01" @default.
- W2783994285 modified "2023-10-14" @default.
- W2783994285 title "Effects of a Single Bout of Aerobic Exercise on Skeletal Muscle Protein Turnover in Mice" @default.
- W2783994285 cites W1580868642 @default.
- W2783994285 cites W1708421313 @default.
- W2783994285 cites W1952358281 @default.
- W2783994285 cites W1960808329 @default.
- W2783994285 cites W1964321721 @default.
- W2783994285 cites W1975915706 @default.
- W2783994285 cites W2005034673 @default.
- W2783994285 cites W2025139842 @default.
- W2783994285 cites W2033676599 @default.
- W2783994285 cites W2036787961 @default.
- W2783994285 cites W2040198130 @default.
- W2783994285 cites W2042568710 @default.
- W2783994285 cites W2044129927 @default.
- W2783994285 cites W2080451230 @default.
- W2783994285 cites W2084459589 @default.
- W2783994285 cites W2096061116 @default.
- W2783994285 cites W2105439389 @default.
- W2783994285 cites W2106309084 @default.
- W2783994285 cites W2114255969 @default.
- W2783994285 cites W2115432680 @default.
- W2783994285 cites W2115928938 @default.
- W2783994285 cites W2161133778 @default.
- W2783994285 cites W2162991803 @default.
- W2783994285 cites W2166156671 @default.
- W2783994285 cites W2167911266 @default.
- W2783994285 cites W2177574648 @default.
- W2783994285 cites W2233627447 @default.
- W2783994285 doi "https://doi.org/10.22374/1875-6859.14.1.2" @default.
- W2783994285 hasPublicationYear "2018" @default.
- W2783994285 type Work @default.
- W2783994285 sameAs 2783994285 @default.
- W2783994285 citedByCount "1" @default.
- W2783994285 crossrefType "journal-article" @default.
- W2783994285 hasAuthorship W2783994285A5044297403 @default.
- W2783994285 hasAuthorship W2783994285A5074329506 @default.
- W2783994285 hasBestOaLocation W27839942851 @default.
- W2783994285 hasConcept C103038586 @default.
- W2783994285 hasConcept C126322002 @default.
- W2783994285 hasConcept C134018914 @default.
- W2783994285 hasConcept C185592680 @default.
- W2783994285 hasConcept C195580219 @default.
- W2783994285 hasConcept C2779959927 @default.
- W2783994285 hasConcept C3019971869 @default.
- W2783994285 hasConcept C3675279 @default.
- W2783994285 hasConcept C55493867 @default.
- W2783994285 hasConcept C71924100 @default.
- W2783994285 hasConceptScore W2783994285C103038586 @default.
- W2783994285 hasConceptScore W2783994285C126322002 @default.
- W2783994285 hasConceptScore W2783994285C134018914 @default.
- W2783994285 hasConceptScore W2783994285C185592680 @default.
- W2783994285 hasConceptScore W2783994285C195580219 @default.
- W2783994285 hasConceptScore W2783994285C2779959927 @default.
- W2783994285 hasConceptScore W2783994285C3019971869 @default.
- W2783994285 hasConceptScore W2783994285C3675279 @default.
- W2783994285 hasConceptScore W2783994285C55493867 @default.
- W2783994285 hasConceptScore W2783994285C71924100 @default.
- W2783994285 hasIssue "1" @default.
- W2783994285 hasLocation W27839942851 @default.
- W2783994285 hasOpenAccess W2783994285 @default.
- W2783994285 hasPrimaryLocation W27839942851 @default.
- W2783994285 hasRelatedWork W1966223210 @default.
- W2783994285 hasRelatedWork W1974568996 @default.
- W2783994285 hasRelatedWork W2016840789 @default.
- W2783994285 hasRelatedWork W2081376013 @default.
- W2783994285 hasRelatedWork W2144576666 @default.
- W2783994285 hasRelatedWork W2309978229 @default.
- W2783994285 hasRelatedWork W2463478234 @default.
- W2783994285 hasRelatedWork W2748952813 @default.
- W2783994285 hasRelatedWork W3028691777 @default.
- W2783994285 hasRelatedWork W3166675052 @default.
- W2783994285 hasVolume "14" @default.
- W2783994285 isParatext "false" @default.
- W2783994285 isRetracted "false" @default.
- W2783994285 magId "2783994285" @default.
- W2783994285 workType "article" @default.