FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2784143313> ?p ?o ?g. }

• W2784143313 endingPage "2822" @default.
• W2784143313 startingPage "2801" @default.
• W2784143313 abstract "Asthma is a heterogeneous disease characterized by chronic airway inflammation that results in a wide spectrum of clinical manifestations. Patients with severe asthma represent a substantial share of consumption of healthcare resources and hospitalization. Moreover, these patients are at risk of increased morbidity and mortality. Recently, several phenotypes and endotypes of asthma have been identified. The identification of specific subtypes of asthma is fundamental for optimizing the clinical benefit of novel treatments. Although in most patients the disease can be controlled by some combination of pharmacologic agents, in some 5-10% of patients the disease remains uncontrolled. Several monoclonal antibodies (mAbs) targeting pathogenetic molecules (e.g., IgE, IL-5, IL- 5R&#945;, IL-4, IL-13, TSLP) are currently available or under development for the treatment of different forms of severe type 2 asthma. The identification of diagnostic and predictive biomarkers (e.g., IgE, blood eosinophil count, FeNO, periostin, etc.) has revolutioned the field of targeted therapy in severe asthma. Monoclonal antibodies targeting Th2-driven inflammation are generally safe in adult patients with moderate-to-severe asthma. The long-term safety of these biologics is a relevant issue that should be addressed. Unfortunately, little is known about non-type 2 asthma. Further studies are needed to identify biomarkers to guide targeted therapies of different forms of non-type 2 asthma." @default.
• W2784143313 created "2018-01-26" @default.
• W2784143313 creator A5020774805 @default.
• W2784143313 creator A5070952651 @default.
• W2784143313 creator A5079235615 @default.
• W2784143313 creator A5079868243 @default.
• W2784143313 creator A5080048332 @default.
• W2784143313 creator A5088550336 @default.
• W2784143313 date "2019-08-26" @default.
• W2784143313 modified "2023-10-13" @default.
• W2784143313 title "Novel Biological Therapies in Severe Asthma: Targeting the Right Trait" @default.
• W2784143313 cites W1192231709 @default.
• W2784143313 cites W1480061809 @default.
• W2784143313 cites W1487097688 @default.
• W2784143313 cites W1488555984 @default.
• W2784143313 cites W1506450640 @default.
• W2784143313 cites W1517597786 @default.
• W2784143313 cites W1524356387 @default.
• W2784143313 cites W1528837080 @default.
• W2784143313 cites W1558665965 @default.
• W2784143313 cites W1596331316 @default.
• W2784143313 cites W1606609712 @default.
• W2784143313 cites W1630159102 @default.
• W2784143313 cites W1659018090 @default.
• W2784143313 cites W1723117224 @default.
• W2784143313 cites W1786797005 @default.
• W2784143313 cites W1802054883 @default.
• W2784143313 cites W1874135794 @default.
• W2784143313 cites W1910182345 @default.
• W2784143313 cites W1916962812 @default.
• W2784143313 cites W1923203539 @default.
• W2784143313 cites W1930202916 @default.
• W2784143313 cites W1949221250 @default.
• W2784143313 cites W1966307092 @default.
• W2784143313 cites W1968699024 @default.
• W2784143313 cites W1969815811 @default.
• W2784143313 cites W1969912242 @default.
• W2784143313 cites W1970271662 @default.
• W2784143313 cites W1973304472 @default.
• W2784143313 cites W1974058875 @default.
• W2784143313 cites W1975409228 @default.
• W2784143313 cites W1975438745 @default.
• W2784143313 cites W1977639139 @default.
• W2784143313 cites W1979026253 @default.
• W2784143313 cites W1979732414 @default.
• W2784143313 cites W1981889336 @default.
• W2784143313 cites W1985951914 @default.
• W2784143313 cites W1986966401 @default.
• W2784143313 cites W1987441485 @default.
• W2784143313 cites W1988758075 @default.
• W2784143313 cites W1989245810 @default.
• W2784143313 cites W1990562459 @default.
• W2784143313 cites W1990775993 @default.
• W2784143313 cites W1992025888 @default.
• W2784143313 cites W1993261989 @default.
• W2784143313 cites W1995784152 @default.
• W2784143313 cites W1995908153 @default.
• W2784143313 cites W1997048122 @default.
• W2784143313 cites W1997452530 @default.
• W2784143313 cites W1998197974 @default.
• W2784143313 cites W1999211886 @default.
• W2784143313 cites W2002980147 @default.
• W2784143313 cites W2003869191 @default.
• W2784143313 cites W2013105339 @default.
• W2784143313 cites W2013908818 @default.
• W2784143313 cites W2014953142 @default.
• W2784143313 cites W2016952830 @default.
• W2784143313 cites W2017336448 @default.
• W2784143313 cites W2019394772 @default.
• W2784143313 cites W2019613010 @default.
• W2784143313 cites W2021852404 @default.
• W2784143313 cites W2022877219 @default.
• W2784143313 cites W2025111901 @default.
• W2784143313 cites W2026119244 @default.
• W2784143313 cites W2028618405 @default.
• W2784143313 cites W2029146675 @default.
• W2784143313 cites W2033946555 @default.
• W2784143313 cites W2037801848 @default.
• W2784143313 cites W2038462158 @default.
• W2784143313 cites W2039930386 @default.
• W2784143313 cites W2040565769 @default.
• W2784143313 cites W2040640809 @default.
• W2784143313 cites W2043046650 @default.
• W2784143313 cites W2044529331 @default.
• W2784143313 cites W2045317929 @default.
• W2784143313 cites W2045873742 @default.
• W2784143313 cites W2046313062 @default.
• W2784143313 cites W2047128789 @default.
• W2784143313 cites W2050042205 @default.
• W2784143313 cites W2050684618 @default.
• W2784143313 cites W2055172715 @default.
• W2784143313 cites W2057490898 @default.
• W2784143313 cites W2058856567 @default.
• W2784143313 cites W2059510350 @default.
• W2784143313 cites W2060015303 @default.
• W2784143313 cites W2060769801 @default.
• W2784143313 cites W2060805982 @default.
• W2784143313 cites W2061435251 @default.

• next