FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2784228679> ?p ?o ?g. }

• W2784228679 endingPage "649" @default.
• W2784228679 startingPage "642" @default.
• W2784228679 abstract "Actins are structural components of the cytoskeleton and muscle, and numerous actin isoforms are found in most organisms. However, many actin isoforms are expressed in distinct patterns allowing each actin to have a specialized function. Numerous studies have demonstrated that actin isoforms both can and cannot compensate for each other under specific circumstances. This allows for an ambiguity of whether isoforms are functionally distinct.In this study, we analyzed mutants of Drosophila Act79B, the predominant actin expressed in the adult jump muscle. Functional and structural analysis of the Act79B mutants found the flies to have normal jumping ability and sarcomere structure. Analysis of actin gene expression determined that expression of Act88F, an actin gene normally expressed in the flight muscles, was significantly up-regulated in the jump muscles of mutants. This indicated that loss of Act79B caused expansion of Act88F expression. When we created double mutants of Act79B and Act88F, this abolished the jump ability of the flies and resulted in severe defects in myofibril formation.These results indicate that Act88F can functionally substitute for Act79B in the jump muscle, and that the functional compensation in actin expression in the jump muscles only occurs through Act88F. Developmental Dynamics 247:642-649, 2018. © 2018 Wiley Periodicals, Inc." @default.
• W2784228679 created "2018-01-26" @default.
• W2784228679 creator A5086418466 @default.
• W2784228679 creator A5089357296 @default.
• W2784228679 date "2018-02-06" @default.
• W2784228679 modified "2023-10-15" @default.
• W2784228679 title "Absence of the Drosophila jump muscle actin Act79B is compensated by up-regulation of<i>Act88F</i>" @default.
• W2784228679 cites W1566143784 @default.
• W2784228679 cites W1586288730 @default.
• W2784228679 cites W1976073942 @default.
• W2784228679 cites W1982850784 @default.
• W2784228679 cites W1995947057 @default.
• W2784228679 cites W1999801226 @default.
• W2784228679 cites W2000301504 @default.
• W2784228679 cites W2010981900 @default.
• W2784228679 cites W2015418548 @default.
• W2784228679 cites W2020207585 @default.
• W2784228679 cites W2039383268 @default.
• W2784228679 cites W2039610005 @default.
• W2784228679 cites W2044625331 @default.
• W2784228679 cites W2056272569 @default.
• W2784228679 cites W2058004965 @default.
• W2784228679 cites W2061986589 @default.
• W2784228679 cites W2062016358 @default.
• W2784228679 cites W2078551003 @default.
• W2784228679 cites W2107277218 @default.
• W2784228679 cites W2109918184 @default.
• W2784228679 cites W2111552778 @default.
• W2784228679 cites W2139074887 @default.
• W2784228679 cites W2139970220 @default.
• W2784228679 cites W2145390973 @default.
• W2784228679 cites W2147495164 @default.
• W2784228679 cites W2156585263 @default.
• W2784228679 cites W2157069654 @default.
• W2784228679 cites W2162805725 @default.
• W2784228679 cites W2169099673 @default.
• W2784228679 cites W2171122741 @default.
• W2784228679 cites W2192080449 @default.
• W2784228679 cites W2200598176 @default.
• W2784228679 cites W2203265148 @default.
• W2784228679 cites W2282547419 @default.
• W2784228679 cites W2304059716 @default.
• W2784228679 cites W251303182 @default.
• W2784228679 cites W56444313 @default.
• W2784228679 cites W69268942 @default.
• W2784228679 doi "https://doi.org/10.1002/dvdy.24616" @default.
• W2784228679 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6118211" @default.
• W2784228679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29318731" @default.
• W2784228679 hasPublicationYear "2018" @default.
• W2784228679 type Work @default.
• W2784228679 sameAs 2784228679 @default.
• W2784228679 citedByCount "11" @default.
• W2784228679 countsByYear W27842286792019 @default.
• W2784228679 countsByYear W27842286792020 @default.
• W2784228679 countsByYear W27842286792021 @default.
• W2784228679 countsByYear W27842286792022 @default.
• W2784228679 countsByYear W27842286792023 @default.
• W2784228679 crossrefType "journal-article" @default.
• W2784228679 hasAuthorship W2784228679A5086418466 @default.
• W2784228679 hasAuthorship W2784228679A5089357296 @default.
• W2784228679 hasBestOaLocation W27842286791 @default.
• W2784228679 hasConcept C104317684 @default.
• W2784228679 hasConcept C105702510 @default.
• W2784228679 hasConcept C125705527 @default.
• W2784228679 hasConcept C143065580 @default.
• W2784228679 hasConcept C207200792 @default.
• W2784228679 hasConcept C53345823 @default.
• W2784228679 hasConcept C54355233 @default.
• W2784228679 hasConcept C55493867 @default.
• W2784228679 hasConcept C68731436 @default.
• W2784228679 hasConcept C6997183 @default.
• W2784228679 hasConcept C7301908 @default.
• W2784228679 hasConcept C86803240 @default.
• W2784228679 hasConcept C95444343 @default.
• W2784228679 hasConceptScore W2784228679C104317684 @default.
• W2784228679 hasConceptScore W2784228679C105702510 @default.
• W2784228679 hasConceptScore W2784228679C125705527 @default.
• W2784228679 hasConceptScore W2784228679C143065580 @default.
• W2784228679 hasConceptScore W2784228679C207200792 @default.
• W2784228679 hasConceptScore W2784228679C53345823 @default.
• W2784228679 hasConceptScore W2784228679C54355233 @default.
• W2784228679 hasConceptScore W2784228679C55493867 @default.
• W2784228679 hasConceptScore W2784228679C68731436 @default.
• W2784228679 hasConceptScore W2784228679C6997183 @default.
• W2784228679 hasConceptScore W2784228679C7301908 @default.
• W2784228679 hasConceptScore W2784228679C86803240 @default.
• W2784228679 hasConceptScore W2784228679C95444343 @default.
• W2784228679 hasFunder F4320332161 @default.
• W2784228679 hasFunder F4320337354 @default.
• W2784228679 hasIssue "4" @default.
• W2784228679 hasLocation W27842286791 @default.
• W2784228679 hasLocation W27842286792 @default.
• W2784228679 hasLocation W27842286793 @default.
• W2784228679 hasLocation W27842286794 @default.
• W2784228679 hasOpenAccess W2784228679 @default.
• W2784228679 hasPrimaryLocation W27842286791 @default.
• W2784228679 hasRelatedWork W182937440 @default.
• W2784228679 hasRelatedWork W1977978400 @default.

• next