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- W2784244956 abstract "Abstract An asymmetric synthesis of ((3 R ,6 R )‐6‐methylpiperidin‐3‐yl)methanol 2 , a potent dual orexin receptor antagonist MK‐6096 1 piperidine core unit, is described. The synthesis utilizes commercial available ( S )‐propylene oxide as a starting material and organocatalyzed asymmetric Michael addition reaction as key step." @default.
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- W2784244956 date "2018-01-04" @default.
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- W2784244956 title "An Asymmetric Synthesis of ((3<i>R</i> ,6<i>R</i> )-6-Methylpiperidine-3-yl)methanol; A Piperidine Core Unit of Potent Dual Orexin Receptor Antagonist MK-6096" @default.
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- W2784244956 doi "https://doi.org/10.1002/slct.201702732" @default.
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