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- W2784270680 abstract "The asymmetric total synthesis of the marine natural product (+)-(3E)-pinnatifidenyne was accomplished. The key features of the synthesis involve the construction of an eight-membered cyclic ether by the abnormally regioselective Pd(0)-catalyzed cyclization, the installation of a double bond in the oxocene skeleton by sequential in situ deconjugative isomerization, and the efficient introduction of the crucial chloride mediated by the substrate-controlled diastereoselective reduction." @default.
- W2784270680 created "2018-01-26" @default.
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- W2784270680 date "2018-01-26" @default.
- W2784270680 modified "2023-10-16" @default.
- W2784270680 title "Asymmetric Total Synthesis of (+)-(3<i>E</i>)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization" @default.
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- W2784270680 doi "https://doi.org/10.1021/acs.joc.7b02937" @default.
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