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- W2784762670 endingPage "123" @default.
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- W2784762670 abstract "Abstract In present time, need for the organ and tissue repair, restoration, and regeneration for patient is in all time high demand and would only increase exponentially due to the longer life expectancy. Even in the given times supply of organ is much shorter than demand due to paucity of donors along with complex biocompatibility issues that result in rejection of the transplants in the recipient who end up receiving the organ. However, with the emergence of tissue engineering, scientists have been constantly investigating to use three-dimensional (3D) scaffold as an alternative source of natural tissue needed for transplantation. These 3D matrices are designed and decorated to mimic the natural extracellular matrix (ECM) of the required tissue thereby enabling easier cellular attachment, proliferation, and subsequently differentiate into fully functional tissues or organs. This approach has undergone tremendous modification since the days where developing scaffold was considered to be challenging to emerging into designing intrinsic network of capillaries by computer-aided printing process. Utilizing 3D printing (3DP) methodology one is able to create ECM-like scaffold with high degree of precision and complexity including fine details at micro and nano-level. In this book chapter, brief history to 3DP of scaffold, polymers used, properties of scaffold, bioinks, scaffold-based viral transduction techniques, and application of 3DP in scaffold fabrication that eventually results in tissue regeneration are discussed. Furthermore, how creation of biofunctional scaffold could ultimately end the longer waiting queues for patient and overcome complexity of tissue transplant." @default.
- W2784762670 created "2018-02-02" @default.
- W2784762670 creator A5066574681 @default.
- W2784762670 date "2018-01-01" @default.
- W2784762670 modified "2023-09-26" @default.
- W2784762670 title "3D bioprinting for scaffold fabrication" @default.
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