FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2785004639> ?p ?o ?g. }

• W2785004639 endingPage "e0006186" @default.
• W2785004639 startingPage "e0006186" @default.
• W2785004639 abstract "The mosquito Aedes aegypti is the primary vector of human arboviral diseases caused by dengue, chikungunya and Zika viruses. Many studies have shown the potential roles of small RNA molecules such as microRNA, small interfering RNA and PIWI-interacting RNA in vector mosquitoes. The function of tRNA fragments (tRF), the newly discovered class of small RNAs, in mosquitoes is not known. In this study, we show that specific tRFs are expressed in significantly differential manner between males and females of Ae. aegypti strains. Specific tRFs also show differential response during developmental transition from larvae to adults, as well as after blood feeding of adult females. The expression pattern of tRFs upon blood feeding varied depending upon if the blood contained dengue virus, and also if the females were treated with antibiotic prior to feeding to cleanse of the gut bacteria. Our findings show that a single tRF derived from the precursor sequences of a tRNA-Gly was differentially expressed between males and females, developmental transitions and also upon blood feeding by females of two laboratory strains that vary in midgut susceptibility to dengue virus infection. The multifaceted functional implications of this specific tRF suggest that biogenesis of small regulatory molecules from a tRNA can have wide ranging effects on key aspects of Ae. aegypti vector biology." @default.
• W2785004639 created "2018-02-02" @default.
• W2785004639 creator A5000057735 @default.
• W2785004639 creator A5035676212 @default.
• W2785004639 creator A5052120081 @default.
• W2785004639 creator A5057795558 @default.
• W2785004639 creator A5061872491 @default.
• W2785004639 creator A5081658959 @default.
• W2785004639 date "2018-01-24" @default.
• W2785004639 modified "2023-10-18" @default.
• W2785004639 title "Multifaceted functional implications of an endogenously expressed tRNA fragment in the vector mosquito Aedes aegypti" @default.
• W2785004639 cites W1801791524 @default.
• W2785004639 cites W1981453005 @default.
• W2785004639 cites W2008313104 @default.
• W2785004639 cites W2008540292 @default.
• W2785004639 cites W2015242285 @default.
• W2785004639 cites W2018731916 @default.
• W2785004639 cites W2025079233 @default.
• W2785004639 cites W2029410145 @default.
• W2785004639 cites W2046236102 @default.
• W2785004639 cites W2051489680 @default.
• W2785004639 cites W2056621266 @default.
• W2785004639 cites W2071286756 @default.
• W2785004639 cites W2073148564 @default.
• W2785004639 cites W2078105351 @default.
• W2785004639 cites W2079467486 @default.
• W2785004639 cites W2081235679 @default.
• W2785004639 cites W2085670818 @default.
• W2785004639 cites W2104005232 @default.
• W2785004639 cites W2106039274 @default.
• W2785004639 cites W2110161291 @default.
• W2785004639 cites W2110905563 @default.
• W2785004639 cites W2112058982 @default.
• W2785004639 cites W2116856071 @default.
• W2785004639 cites W2134974969 @default.
• W2785004639 cites W2142584500 @default.
• W2785004639 cites W2148173819 @default.
• W2785004639 cites W2151435150 @default.
• W2785004639 cites W2155396750 @default.
• W2785004639 cites W2161868542 @default.
• W2785004639 cites W2171158206 @default.
• W2785004639 cites W2201382378 @default.
• W2785004639 cites W2262003432 @default.
• W2785004639 cites W2281309807 @default.
• W2785004639 cites W2286052994 @default.
• W2785004639 cites W2333945626 @default.
• W2785004639 cites W2406404683 @default.
• W2785004639 cites W2415209296 @default.
• W2785004639 cites W2417123930 @default.
• W2785004639 cites W2516522739 @default.
• W2785004639 cites W2522726689 @default.
• W2785004639 cites W2543470218 @default.
• W2785004639 cites W2551434907 @default.
• W2785004639 cites W2551536786 @default.
• W2785004639 cites W2554225141 @default.
• W2785004639 cites W2571283472 @default.
• W2785004639 cites W2584813312 @default.
• W2785004639 cites W4250052351 @default.
• W2785004639 doi "https://doi.org/10.1371/journal.pntd.0006186" @default.
• W2785004639 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5783352" @default.
• W2785004639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29364883" @default.
• W2785004639 hasPublicationYear "2018" @default.
• W2785004639 type Work @default.
• W2785004639 sameAs 2785004639 @default.
• W2785004639 citedByCount "10" @default.
• W2785004639 countsByYear W27850046392019 @default.
• W2785004639 countsByYear W27850046392020 @default.
• W2785004639 countsByYear W27850046392021 @default.
• W2785004639 countsByYear W27850046392022 @default.
• W2785004639 countsByYear W27850046392023 @default.
• W2785004639 crossrefType "journal-article" @default.
• W2785004639 hasAuthorship W2785004639A5000057735 @default.
• W2785004639 hasAuthorship W2785004639A5035676212 @default.
• W2785004639 hasAuthorship W2785004639A5052120081 @default.
• W2785004639 hasAuthorship W2785004639A5057795558 @default.
• W2785004639 hasAuthorship W2785004639A5061872491 @default.
• W2785004639 hasAuthorship W2785004639A5081658959 @default.
• W2785004639 hasBestOaLocation W27850046391 @default.
• W2785004639 hasConcept C104317684 @default.
• W2785004639 hasConcept C131934819 @default.
• W2785004639 hasConcept C159047783 @default.
• W2785004639 hasConcept C173758957 @default.
• W2785004639 hasConcept C18903297 @default.
• W2785004639 hasConcept C2522874641 @default.
• W2785004639 hasConcept C2777775583 @default.
• W2785004639 hasConcept C2779341050 @default.
• W2785004639 hasConcept C2779635636 @default.
• W2785004639 hasConcept C2780688631 @default.
• W2785004639 hasConcept C2781273456 @default.
• W2785004639 hasConcept C40767141 @default.
• W2785004639 hasConcept C533803919 @default.
• W2785004639 hasConcept C54355233 @default.
• W2785004639 hasConcept C67705224 @default.
• W2785004639 hasConcept C86803240 @default.
• W2785004639 hasConcept C92087593 @default.
• W2785004639 hasConceptScore W2785004639C104317684 @default.
• W2785004639 hasConceptScore W2785004639C131934819 @default.
• W2785004639 hasConceptScore W2785004639C159047783 @default.

• next