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- W2785042616 abstract "Proton pump inhibitors (PPI) are currently the most effective class of antisecretory drugs widely used in the treatment of non-ulcer dyspepsia, reflux esophagitis and GERD, peptic ulcer disease and H. pilory infection, as well as NSAID-associated gastric lesions. Despite the common mechanism of action and pharmacological effects of this class of drugs, there is clinical inter-individual variability of their effect on acid production determined by pharmacokinetic and pharmacogenetic factors. As a result, the clinical efficacy of treatment of acid-base disorders and eradication of H. pilory is decreased." @default.
- W2785042616 created "2018-02-02" @default.
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- W2785042616 date "2015-12-01" @default.
- W2785042616 modified "2023-09-25" @default.
- W2785042616 title "Pharmacogenetics of proton pump inhibitors" @default.
- W2785042616 doi "https://doi.org/10.21518/2079-701x-2015-17-96-103" @default.
- W2785042616 hasPublicationYear "2015" @default.
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