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• W2785296608 abstract "Seven compounds; Vismiaquinone A (1), 7-geranyloxy-1,3-dihydroxyxanthone (2), Cochinchinone G (3), Fuscaxanthone E (4), g-tocotrienol (5), δ-tocotrienol (6), and a-tocopherol (7) were isolated from fruits and leaves of Cratoxylum cochinchinense. The structures of all isolated compounds were elucidated by basic NMR spectroscopy (1H, 13C, COSY, HSQC and HMBC) and compared with previous literatures. Interestingly, g-tocotrienol (5) and a-tocopherol (7) were the first time being isolated from C. cochinchinense. The chemical constituents of C. cochinchinense such as g-tocotrienol (5), δ-tocotrienol (6), and a-tocopherol (7) are vitamin E derivatives that have been used for cosmetic ingredients. Thus, this plant extract should be promising probability for applying to cosmetic ingredients. Furthermore, all isolated compounds were also tested for in vitro cytotoxic activity against five human cancer cell lines; breast (BT474), lung (ChaGo-K-1), liver (HepG2), gastric (KATO-III), and colon (SW-620) cancer cell lines by MTT assay method. The cytotoxic activity of compound 3 against SW-620 (colon cancer cell line, IC50 4.64 mg/mL) was found to be stronger than other compounds." @default.
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• W2785296608 date "2017-07-17" @default.
• W2785296608 modified "2023-09-23" @default.
• W2785296608 title "Chemical Constituents of Fruits and Leaves of Cratoxylum cochinchinense and Their Cytotoxic Activities" @default.
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