FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2785332302> ?p ?o ?g. }

• W2785332302 abstract "Abstract Probiotics such as L . plantarum WCFS1 can modulate immune responses in healthy subjects but how this occurs is still largely unknown. Immune-sampling in the Peyer Patches has been suggested to be one of the mechanisms. Here we studied the systemic and intestinal immune effects in combination with a trafficking study through the intestine of a well-established immunomodulating probiotic, i.e. L . plantarum WCFS1. We demonstrate that not more than 2–3 bacteria were sampled and in many animals not any bacterium could be found in the PP. Despite this, L . plantarum was associated with a strong increase in infiltration of regulatory CD103 + DCs and generation of regulatory T cells in the spleen. Also, a reduced splenic T helper cell cytokine response was observed after ex vivo restimulation. L . plantarum enhanced Treg cells and attenuated the T helper 2 response in healthy mice. We demonstrate that, in healthy mice, immune sampling is a rare phenomenon and not required for immunomodulation. Also in absence of any sampling immune activation was found illustrating that host-microbe interaction on the Peyer Patches was enough to induce immunomodulation of DCs and T-cells." @default.
• W2785332302 created "2018-02-23" @default.
• W2785332302 creator A5002327084 @default.
• W2785332302 creator A5024340021 @default.
• W2785332302 creator A5038062705 @default.
• W2785332302 creator A5050797896 @default.
• W2785332302 creator A5058228468 @default.
• W2785332302 creator A5063717190 @default.
• W2785332302 creator A5086665853 @default.
• W2785332302 date "2018-01-29" @default.
• W2785332302 modified "2023-09-30" @default.
• W2785332302 title "L. plantarum WCFS1 enhances Treg frequencies by activating DCs even in absence of sampling of bacteria in the Peyer Patches" @default.
• W2785332302 cites W1508547562 @default.
• W2785332302 cites W1543982748 @default.
• W2785332302 cites W1658108044 @default.
• W2785332302 cites W1798992768 @default.
• W2785332302 cites W1845975704 @default.
• W2785332302 cites W1893103942 @default.
• W2785332302 cites W1906564878 @default.
• W2785332302 cites W1978319670 @default.
• W2785332302 cites W1987772295 @default.
• W2785332302 cites W1988752472 @default.
• W2785332302 cites W1991804457 @default.
• W2785332302 cites W2003111539 @default.
• W2785332302 cites W2006862991 @default.
• W2785332302 cites W2012501342 @default.
• W2785332302 cites W2029945723 @default.
• W2785332302 cites W2033490676 @default.
• W2785332302 cites W2034030958 @default.
• W2785332302 cites W2034598453 @default.
• W2785332302 cites W2047780224 @default.
• W2785332302 cites W2057619726 @default.
• W2785332302 cites W2059839808 @default.
• W2785332302 cites W2075657590 @default.
• W2785332302 cites W2083979121 @default.
• W2785332302 cites W2085355903 @default.
• W2785332302 cites W2088553840 @default.
• W2785332302 cites W2102672175 @default.
• W2785332302 cites W2105758599 @default.
• W2785332302 cites W2112714728 @default.
• W2785332302 cites W2123771309 @default.
• W2785332302 cites W2128535769 @default.
• W2785332302 cites W2129539892 @default.
• W2785332302 cites W2132241088 @default.
• W2785332302 cites W2137035993 @default.
• W2785332302 cites W2143544846 @default.
• W2785332302 cites W2146068085 @default.
• W2785332302 cites W2146371543 @default.
• W2785332302 cites W2148494803 @default.
• W2785332302 cites W2149547237 @default.
• W2785332302 cites W2154004944 @default.
• W2785332302 cites W2157012766 @default.
• W2785332302 cites W2157650196 @default.
• W2785332302 cites W2160579940 @default.
• W2785332302 cites W2163590547 @default.
• W2785332302 cites W2171980652 @default.
• W2785332302 cites W2214326488 @default.
• W2785332302 cites W2292128850 @default.
• W2785332302 cites W2399307124 @default.
• W2785332302 cites W2742704634 @default.
• W2785332302 doi "https://doi.org/10.1038/s41598-018-20243-1" @default.
• W2785332302 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5788989" @default.
• W2785332302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29379071" @default.
• W2785332302 hasPublicationYear "2018" @default.
• W2785332302 type Work @default.
• W2785332302 sameAs 2785332302 @default.
• W2785332302 citedByCount "12" @default.
• W2785332302 countsByYear W27853323022019 @default.
• W2785332302 countsByYear W27853323022020 @default.
• W2785332302 countsByYear W27853323022021 @default.
• W2785332302 countsByYear W27853323022023 @default.
• W2785332302 crossrefType "journal-article" @default.
• W2785332302 hasAuthorship W2785332302A5002327084 @default.
• W2785332302 hasAuthorship W2785332302A5024340021 @default.
• W2785332302 hasAuthorship W2785332302A5038062705 @default.
• W2785332302 hasAuthorship W2785332302A5050797896 @default.
• W2785332302 hasAuthorship W2785332302A5058228468 @default.
• W2785332302 hasAuthorship W2785332302A5063717190 @default.
• W2785332302 hasAuthorship W2785332302A5086665853 @default.
• W2785332302 hasBestOaLocation W27853323021 @default.
• W2785332302 hasConcept C203014093 @default.
• W2785332302 hasConcept C2778019737 @default.
• W2785332302 hasConcept C2780931953 @default.
• W2785332302 hasConcept C86803240 @default.
• W2785332302 hasConcept C8891405 @default.
• W2785332302 hasConcept C89423630 @default.
• W2785332302 hasConceptScore W2785332302C203014093 @default.
• W2785332302 hasConceptScore W2785332302C2778019737 @default.
• W2785332302 hasConceptScore W2785332302C2780931953 @default.
• W2785332302 hasConceptScore W2785332302C86803240 @default.
• W2785332302 hasConceptScore W2785332302C8891405 @default.
• W2785332302 hasConceptScore W2785332302C89423630 @default.
• W2785332302 hasIssue "1" @default.
• W2785332302 hasLocation W27853323021 @default.
• W2785332302 hasLocation W278533230210 @default.
• W2785332302 hasLocation W278533230211 @default.
• W2785332302 hasLocation W27853323022 @default.
• W2785332302 hasLocation W27853323023 @default.
• W2785332302 hasLocation W27853323024 @default.
• W2785332302 hasLocation W27853323025 @default.

• next