Matches in SemOpenAlex for { <https://semopenalex.org/work/W2785431145> ?p ?o ?g. }
- W2785431145 endingPage "359" @default.
- W2785431145 startingPage "351" @default.
- W2785431145 abstract "The potential safety hazards associated with the Suzuki–Miyaura cross-coupling of aryl bromides with vinylboron species were evaluated. In the Suzuki–Miyaura cross-coupling of 1-bromo-3-(trifluoromethyl)benzene with potassium vinyltrifluoroborate in the presence of potassium carbonate (K2CO3) in 9:1 dimethyl sulfoxide (DMSO)/water at 80 °C, the thermal profile revealed a significant exotherm upon the addition of catalytic 1,1′-bis(diphenylphosphino)ferrocene palladium(II) dichloride [Pd(dppf)Cl2]. Further investigations indicated that the exotherm was consistently higher and the reactions were faster in the studied aqueous systems compared to anhydrous conditions. Although under anhydrous conditions the exotherms were comparable among the studied cases, the rate of the exotherm was highly dependent on the choice of aryl electrophile, solvent, base, catalyst, as well as vinylboron species. In many of the studied cases the maximum temperature of a synthesis reaction (MTSR) was considerably higher than the boiling point of the solvent and/or the onset temperature of the DMSO decomposition, indicating that in the absence of active cooling the system could quickly exceed the boiling point of the solvent or trigger the decomposition of the reaction mixture to result in a runaway reaction." @default.
- W2785431145 created "2018-02-23" @default.
- W2785431145 creator A5005012519 @default.
- W2785431145 creator A5019470495 @default.
- W2785431145 creator A5040455246 @default.
- W2785431145 creator A5041210716 @default.
- W2785431145 creator A5073267863 @default.
- W2785431145 creator A5058952808 @default.
- W2785431145 date "2018-02-01" @default.
- W2785431145 modified "2023-10-09" @default.
- W2785431145 title "Evaluation of Potential Safety Hazards Associated with the Suzuki–Miyaura Cross-Coupling of Aryl Bromides with Vinylboron Species" @default.
- W2785431145 cites W1183155069 @default.
- W2785431145 cites W1966002538 @default.
- W2785431145 cites W1978890358 @default.
- W2785431145 cites W1983655940 @default.
- W2785431145 cites W1990770951 @default.
- W2785431145 cites W1993666102 @default.
- W2785431145 cites W1994689089 @default.
- W2785431145 cites W2004867175 @default.
- W2785431145 cites W2008890070 @default.
- W2785431145 cites W2013806472 @default.
- W2785431145 cites W2016757577 @default.
- W2785431145 cites W2026388793 @default.
- W2785431145 cites W2038011052 @default.
- W2785431145 cites W2049101910 @default.
- W2785431145 cites W2052872009 @default.
- W2785431145 cites W2055524673 @default.
- W2785431145 cites W2055912794 @default.
- W2785431145 cites W2056045888 @default.
- W2785431145 cites W2070660884 @default.
- W2785431145 cites W2073940604 @default.
- W2785431145 cites W2088736894 @default.
- W2785431145 cites W2088866324 @default.
- W2785431145 cites W2092359276 @default.
- W2785431145 cites W2134035064 @default.
- W2785431145 cites W2143856302 @default.
- W2785431145 cites W2153587535 @default.
- W2785431145 cites W2156665818 @default.
- W2785431145 cites W2159365757 @default.
- W2785431145 cites W2171137596 @default.
- W2785431145 cites W2175063038 @default.
- W2785431145 cites W2232099300 @default.
- W2785431145 cites W2294824759 @default.
- W2785431145 cites W2321884210 @default.
- W2785431145 cites W2325324707 @default.
- W2785431145 cites W2326796241 @default.
- W2785431145 cites W2326950951 @default.
- W2785431145 cites W2334060382 @default.
- W2785431145 cites W2415475214 @default.
- W2785431145 cites W2496572958 @default.
- W2785431145 cites W2560538353 @default.
- W2785431145 cites W2571032574 @default.
- W2785431145 cites W2727583559 @default.
- W2785431145 cites W2739209199 @default.
- W2785431145 cites W2743540123 @default.
- W2785431145 cites W2765163689 @default.
- W2785431145 cites W2950998795 @default.
- W2785431145 cites W2951717815 @default.
- W2785431145 cites W2951812373 @default.
- W2785431145 cites W2952297080 @default.
- W2785431145 doi "https://doi.org/10.1021/acs.oprd.8b00001" @default.
- W2785431145 hasPublicationYear "2018" @default.
- W2785431145 type Work @default.
- W2785431145 sameAs 2785431145 @default.
- W2785431145 citedByCount "19" @default.
- W2785431145 countsByYear W27854311452018 @default.
- W2785431145 countsByYear W27854311452019 @default.
- W2785431145 countsByYear W27854311452020 @default.
- W2785431145 countsByYear W27854311452021 @default.
- W2785431145 countsByYear W27854311452022 @default.
- W2785431145 countsByYear W27854311452023 @default.
- W2785431145 crossrefType "journal-article" @default.
- W2785431145 hasAuthorship W2785431145A5005012519 @default.
- W2785431145 hasAuthorship W2785431145A5019470495 @default.
- W2785431145 hasAuthorship W2785431145A5040455246 @default.
- W2785431145 hasAuthorship W2785431145A5041210716 @default.
- W2785431145 hasAuthorship W2785431145A5058952808 @default.
- W2785431145 hasAuthorship W2785431145A5073267863 @default.
- W2785431145 hasBestOaLocation W27854311451 @default.
- W2785431145 hasConcept C147789679 @default.
- W2785431145 hasConcept C155647269 @default.
- W2785431145 hasConcept C160434732 @default.
- W2785431145 hasConcept C161790260 @default.
- W2785431145 hasConcept C17525397 @default.
- W2785431145 hasConcept C178790620 @default.
- W2785431145 hasConcept C179104552 @default.
- W2785431145 hasConcept C185592680 @default.
- W2785431145 hasConcept C187714232 @default.
- W2785431145 hasConcept C188027245 @default.
- W2785431145 hasConcept C2777237805 @default.
- W2785431145 hasConcept C2780263894 @default.
- W2785431145 hasConcept C2780291738 @default.
- W2785431145 hasConcept C2780471494 @default.
- W2785431145 hasConcept C2781076698 @default.
- W2785431145 hasConcept C48424934 @default.
- W2785431145 hasConcept C502130503 @default.
- W2785431145 hasConcept C52859227 @default.
- W2785431145 hasConceptScore W2785431145C147789679 @default.