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- W2785809652 abstract "Objective To identify and characterize an opioids-related adverse drug event (ADE) usingnaloxone as a trigger tool and to determine the causes of preventable ADEs.Methods An observation retrospective study was conducted by reviewing medical records of hospitalized patients who received naloxone from January 2015 to December2016 at the University hospital. The researchers systemically reviewed the medical records to identify ADE cases which were further reviewed to determine whether they werepreventable, and their causes as well as a severity rating.Results Out of the one hundred and eighty seven-cases reviewed, 31 events were identified as ADEs (16.58 %). The incidence of opioids-related ADEs was 0.19 events per 100admissions and 0.16 events per 1,000 patient-days. Twenty (64.52%) out of 31 eventswere identi fied as preventable ADEs. The severity of 19 events were classi fied as E. Inappropriate opioid doses was the most causes of preventable ADEs, which occurred duringthe prescribing phase (11 events, 55%) The majority of ADEs cases were female (70.97%)and the median age was 65 years (55-74). Morphine was the most frequently taken drugthat caused ADEs (48.39).Conclusions Using naloxone as a trigger tool helps to increase the total number of identifi ed opioids-related ADEs. Most of these ADEs were classi fied as preventable ADEs. Preventable ADEs most often occurred during the prescribing phase." @default.
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- W2785809652 date "2018-01-01" @default.
- W2785809652 modified "2023-09-24" @default.
- W2785809652 title "To identify and characterize an opioids-related adverse drug event (ADE) using naloxone as a trigger tool and to determine the causes of preventable ADEs" @default.
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