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- W278612978 abstract "For many years transurethral resection of prostate has been established as the optimum treatment for benign prostatic hyperplasia. This viewpoint is now being challenged because of criticism of the operation itself and by the availability of a bewildering variety of alternative treatments (box). Most are recent innovations, and results of long term follow up studies are not yet available. Unfortunately, claims for their superiority have sometimes been exaggerated by their enthusiastic proponents.Treatments for benign prostatic hyperplasiaPhysicalBalloon dilatationIntraurethral implants - Spirals, stentsMicrowave thermotherapy - Transrectal, transurethralLaser - “Side fire” ablation, contact incision, transurethral needle ablationUltrasonic tissue - External sourceDisintegration - Transurethral probeCryosurgery Transurethral resection or incision of prostatePharmacotherapy(alpha) Adrenergic antagonists - for example, prazosin, indoramin, terazosin, doxazosinAntiandrogen treatment - Surgical castration, medical castration (luteinising hormone releasing hormone analogues, cyproterone, flutamideSpecific prostatic androgen inhibitor - 5(alpha) reductase inhibitor (finasteride)Recent reports of an unexpectedly high incidence of complications after transurethral resection of prostate need to be taken seriously, but few would agree that the early and late mortality figures published by Roos et al are typical of modern practice.1 Mortality is influenced by many factors that have not necessarily been evaluated or reported but could bias results. More obviously these include the skill and continuing experience of the surgeon, the size of the prostate resected (which in turn influences duration of resection and hence blood loss and irrigant absorption), and cardiovascular …" @default.
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- W278612978 title "Controversies in Management: Alternatives are still unproved" @default.
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- W278612978 doi "https://doi.org/10.1136/bmj.309.6956.717" @default.
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