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- W2786130165 abstract "A bifunctional squaramide-catalyzed reaction of pyrazolin-5-ones with o-quinone methides in situ generated from 2-(1-tosylalkyl)phenols has been successfully developed, providing a facile access to chiral pyrazolones with high enantioselectivities. In addition, the chiral spiropyrazolones with adjacent tertiary and quaternary stereogenic centers can also be obtained through cascade chlorination/cyclization of the chiral pyrazolones." @default.
- W2786130165 created "2018-02-23" @default.
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- W2786130165 date "2018-02-08" @default.
- W2786130165 modified "2023-10-12" @default.
- W2786130165 title "Synthesis of Chiral Pyrazolone and Spiropyrazolone Derivatives through Squaramide-Catalyzed Reaction of Pyrazolin-5-ones with <i>o</i>-Quinone Methides" @default.
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- W2786130165 doi "https://doi.org/10.1021/acs.orglett.8b00025" @default.
- W2786130165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29420039" @default.
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