FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2786174913> ?p ?o ?g. }

• W2786174913 endingPage "480" @default.
• W2786174913 startingPage "472" @default.
• W2786174913 abstract "OBJECTIVE The purpose of this study was to quantify the reproducibility, temporal stability, and functional correlation of diffusion MR characteristics in the spinal cord in patients with cervical stenosis with or without myelopathy. The association between longitudinal diffusion tensor imaging (DTI) measurements and serial neurological function assessment was explored at both the group and individual level. METHODS Sixty-six nonoperatively treated patients with cervical stenosis were prospectively followed (3 months to > 5 years) using synchronous serial MRI and functional outcome assessment. A total of 183 separate MRI examinations were performed, separated by at least 3 months, and each patient had a minimum of 2 MRI scans (range 2–5 scans). Anatomical and DTI measurements were performed within the spinal cord at the C1–2 region as well as at the area of highest compression. Coefficients of variance (COVs) were compared across measurements in both reference tissue and areas of compression for anatomical measurements, fractional anisotropy (FA), and mean diffusivity (MD). The correlation between diffusion MR measures at the site of compression and evaluations of neurological function assessed using the modified Japanese Orthopaedic Association (mJOA) scale at multiple time points was evaluated. RESULTS The COVs for anatomical measurements (Torg ratio and canal diameter) were between 7% and 10%. The median COV for FA measurements at the site of compression was 9%, and for reference tissue at C1–2 it was 6%. The median COV for MD at the site of compression was approximately 12%, and for reference tissue at C1–2 it was 10%. The FA and MD measurements of C1–2 averaged 0.61 and 0.91 μm 2 /msec, respectively, whereas the FA and MD measurements at the site of compression averaged 0.51 and 1.26 μm 2 /msec, respectively. Both FA (slope = 0.037; R 2 = 0.3281, p < 0.0001) and MD (slope = −0.074; R 2 = 0.1101, p = 0.0084) were significantly correlated with the mJOA score. The FA decreased by approximately 0.032 units per mJOA unit decrease (R 2 = 0.2037, p < 0.0001), whereas the MD was increased by approximately 0.084 μm 2 /msec for every mJOA unit decrease (R 2 = 0.1016, p < 0.0001). CONCLUSIONS Quantitative DTI measurements of the spinal cord in patients with cervical stenosis with or without myelopathy have a median COV of 5%–10%, similar to anatomical measurements. The reproducibility of these measurements and significant correlation with functional outcome status suggest a potential role in the evaluation and longitudinal surveillance of nonoperatively treated patients. With respect to the specific DTI measurements, FA within the spinal cord appears slightly more sensitive to neurological function and more stable than measures of MD. Therefore, DTI of the spinal cord may be a clinically feasible imaging technique for longitudinally monitoring patients with cervical spondylotic myelopathy." @default.
• W2786174913 created "2018-02-23" @default.
• W2786174913 creator A5011331705 @default.
• W2786174913 creator A5017398771 @default.
• W2786174913 creator A5017671349 @default.
• W2786174913 creator A5025351354 @default.
• W2786174913 creator A5060591628 @default.
• W2786174913 date "2018-05-01" @default.
• W2786174913 modified "2023-10-18" @default.
• W2786174913 title "Reproducibility, temporal stability, and functional correlation of diffusion MR measurements within the spinal cord in patients with asymptomatic cervical stenosis or cervical myelopathy" @default.
• W2786174913 cites W1493673378 @default.
• W2786174913 cites W150586769 @default.
• W2786174913 cites W1846737937 @default.
• W2786174913 cites W1964778973 @default.
• W2786174913 cites W1986766009 @default.
• W2786174913 cites W1996053693 @default.
• W2786174913 cites W1997009068 @default.
• W2786174913 cites W2001334286 @default.
• W2786174913 cites W2001414937 @default.
• W2786174913 cites W2006458229 @default.
• W2786174913 cites W2010358773 @default.
• W2786174913 cites W2024727684 @default.
• W2786174913 cites W2028489269 @default.
• W2786174913 cites W2035093797 @default.
• W2786174913 cites W2043748208 @default.
• W2786174913 cites W2049970995 @default.
• W2786174913 cites W2051644857 @default.
• W2786174913 cites W2063021827 @default.
• W2786174913 cites W2065688740 @default.
• W2786174913 cites W2070424326 @default.
• W2786174913 cites W2076211539 @default.
• W2786174913 cites W2079151899 @default.
• W2786174913 cites W2079344466 @default.
• W2786174913 cites W2091630420 @default.
• W2786174913 cites W2106527526 @default.
• W2786174913 cites W2107445194 @default.
• W2786174913 cites W2121481688 @default.
• W2786174913 cites W2125515476 @default.
• W2786174913 cites W2133156432 @default.
• W2786174913 cites W2134678666 @default.
• W2786174913 cites W2138014276 @default.
• W2786174913 cites W2138330265 @default.
• W2786174913 cites W2142914486 @default.
• W2786174913 cites W2143772578 @default.
• W2786174913 cites W2144312781 @default.
• W2786174913 cites W2156499354 @default.
• W2786174913 cites W2158987047 @default.
• W2786174913 cites W2165176033 @default.
• W2786174913 cites W2168477871 @default.
• W2786174913 cites W2169329866 @default.
• W2786174913 cites W2214743382 @default.
• W2786174913 cites W2303633563 @default.
• W2786174913 cites W2326799623 @default.
• W2786174913 cites W2347466196 @default.
• W2786174913 cites W2398144930 @default.
• W2786174913 cites W2415957005 @default.
• W2786174913 cites W4211262326 @default.
• W2786174913 cites W4247637568 @default.
• W2786174913 cites W4254775857 @default.
• W2786174913 doi "https://doi.org/10.3171/2017.7.spine176" @default.
• W2786174913 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5930078" @default.
• W2786174913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29424671" @default.
• W2786174913 hasPublicationYear "2018" @default.
• W2786174913 type Work @default.
• W2786174913 sameAs 2786174913 @default.
• W2786174913 citedByCount "12" @default.
• W2786174913 countsByYear W27861749132019 @default.
• W2786174913 countsByYear W27861749132020 @default.
• W2786174913 countsByYear W27861749132021 @default.
• W2786174913 countsByYear W27861749132022 @default.
• W2786174913 countsByYear W27861749132023 @default.
• W2786174913 crossrefType "journal-article" @default.
• W2786174913 hasAuthorship W2786174913A5011331705 @default.
• W2786174913 hasAuthorship W2786174913A5017398771 @default.
• W2786174913 hasAuthorship W2786174913A5017671349 @default.
• W2786174913 hasAuthorship W2786174913A5025351354 @default.
• W2786174913 hasAuthorship W2786174913A5060591628 @default.
• W2786174913 hasBestOaLocation W27861749131 @default.
• W2786174913 hasConcept C104709138 @default.
• W2786174913 hasConcept C105702510 @default.
• W2786174913 hasConcept C105795698 @default.
• W2786174913 hasConcept C118552586 @default.
• W2786174913 hasConcept C126838900 @default.
• W2786174913 hasConcept C141071460 @default.
• W2786174913 hasConcept C143409427 @default.
• W2786174913 hasConcept C149550507 @default.
• W2786174913 hasConcept C159985019 @default.
• W2786174913 hasConcept C171606756 @default.
• W2786174913 hasConcept C180016635 @default.
• W2786174913 hasConcept C192562407 @default.
• W2786174913 hasConcept C2776944266 @default.
• W2786174913 hasConcept C2777604421 @default.
• W2786174913 hasConcept C2777910003 @default.
• W2786174913 hasConcept C2778231337 @default.
• W2786174913 hasConcept C2779632786 @default.
• W2786174913 hasConcept C2780007028 @default.
• W2786174913 hasConcept C2780175798 @default.
• W2786174913 hasConcept C2780775167 @default.

• next