FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2786251472> ?p ?o ?g. }

• W2786251472 endingPage "202" @default.
• W2786251472 startingPage "197" @default.
• W2786251472 abstract "Until recently, a gene polymorphism in the promoter region of endothelial nitric oxide synthase has been suggested as a risk factor for thromboangiitis obliterans (TAO) development. The aim of this study was to compare the metabolites of nitric oxide (NO) and its backup, heme-oxygenase-1 (HMOX1), between TAO patients and those of a smoking control group matched by race, age, sex, and smoking habits.Twenty-four male Caucasian TAO patients and 20 male Caucasian controls enrolled in the study. Their smoking habits were matched based on the serum cotinine levels of 17 of the TAO patients and the 20 controls. A colorimetric kit was used to measure NO, and an enzyme-linked immunosorbent assay kit was used to measure cotinine and HMOX1 levels.The mean serum level of NO metabolites in the TAO group was significantly less than in the controls (p = 0.03) and also significantly less in the patients with below-knee amputations than in non-amputees (p= 0.018). Also, HMOX1 was significantly greater in the TAO patients than in the controls (p= 0.01). No significant correlation was found between NO and HMOX1 (p = 0.054).Nitric oxide may play a pivotal role in TAO development and its outcome. However, the intact HMOX1 pathway may demonstrate the unique role of NO, which cannot be compensated for by HMOX1 and whose absence may make patients susceptible to developing TAO. In addition, another pathway besides NO, with influence on vascular tone and hemostasis, might be involved in TAO development, such as the autonomic nervous system. Further studies are suggested regarding these issues." @default.
• W2786251472 created "2018-02-23" @default.
• W2786251472 creator A5002070527 @default.
• W2786251472 creator A5007630255 @default.
• W2786251472 creator A5025721934 @default.
• W2786251472 creator A5044621774 @default.
• W2786251472 creator A5045714862 @default.
• W2786251472 creator A5050273143 @default.
• W2786251472 creator A5085646421 @default.
• W2786251472 date "2018-04-01" @default.
• W2786251472 modified "2023-09-28" @default.
• W2786251472 title "The Status of Nitric Oxide and its Backup, Heme Oxygenase 1, in Thromboangiitis Obliterans." @default.
• W2786251472 cites W1506693614 @default.
• W2786251472 cites W1587935192 @default.
• W2786251472 cites W1968791438 @default.
• W2786251472 cites W1990481028 @default.
• W2786251472 cites W1995117391 @default.
• W2786251472 cites W2006861037 @default.
• W2786251472 cites W2011237115 @default.
• W2786251472 cites W2012840031 @default.
• W2786251472 cites W2020466267 @default.
• W2786251472 cites W2022044980 @default.
• W2786251472 cites W2023001867 @default.
• W2786251472 cites W2053179924 @default.
• W2786251472 cites W2091857554 @default.
• W2786251472 cites W2123603955 @default.
• W2786251472 cites W2125127136 @default.
• W2786251472 cites W2127095655 @default.
• W2786251472 cites W2131173683 @default.
• W2786251472 cites W2136417428 @default.
• W2786251472 cites W2139371740 @default.
• W2786251472 cites W2142121457 @default.
• W2786251472 cites W2263363622 @default.
• W2786251472 cites W2312423837 @default.
• W2786251472 cites W2405431611 @default.
• W2786251472 cites W2471194889 @default.
• W2786251472 cites W2514571355 @default.
• W2786251472 cites W80727668 @default.
• W2786251472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5941125" @default.
• W2786251472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29766003" @default.
• W2786251472 hasPublicationYear "2018" @default.
• W2786251472 type Work @default.
• W2786251472 sameAs 2786251472 @default.
• W2786251472 citedByCount "3" @default.
• W2786251472 countsByYear W27862514722020 @default.
• W2786251472 countsByYear W27862514722021 @default.
• W2786251472 crossrefType "journal-article" @default.
• W2786251472 hasAuthorship W2786251472A5002070527 @default.
• W2786251472 hasAuthorship W2786251472A5007630255 @default.
• W2786251472 hasAuthorship W2786251472A5025721934 @default.
• W2786251472 hasAuthorship W2786251472A5044621774 @default.
• W2786251472 hasAuthorship W2786251472A5045714862 @default.
• W2786251472 hasAuthorship W2786251472A5050273143 @default.
• W2786251472 hasAuthorship W2786251472A5085646421 @default.
• W2786251472 hasConcept C126322002 @default.
• W2786251472 hasConcept C134018914 @default.
• W2786251472 hasConcept C181199279 @default.
• W2786251472 hasConcept C2776217839 @default.
• W2786251472 hasConcept C2777622882 @default.
• W2786251472 hasConcept C2779219270 @default.
• W2786251472 hasConcept C2779730776 @default.
• W2786251472 hasConcept C519581460 @default.
• W2786251472 hasConcept C55493867 @default.
• W2786251472 hasConcept C71924100 @default.
• W2786251472 hasConcept C86803240 @default.
• W2786251472 hasConcept C90924648 @default.
• W2786251472 hasConceptScore W2786251472C126322002 @default.
• W2786251472 hasConceptScore W2786251472C134018914 @default.
• W2786251472 hasConceptScore W2786251472C181199279 @default.
• W2786251472 hasConceptScore W2786251472C2776217839 @default.
• W2786251472 hasConceptScore W2786251472C2777622882 @default.
• W2786251472 hasConceptScore W2786251472C2779219270 @default.
• W2786251472 hasConceptScore W2786251472C2779730776 @default.
• W2786251472 hasConceptScore W2786251472C519581460 @default.
• W2786251472 hasConceptScore W2786251472C55493867 @default.
• W2786251472 hasConceptScore W2786251472C71924100 @default.
• W2786251472 hasConceptScore W2786251472C86803240 @default.
• W2786251472 hasConceptScore W2786251472C90924648 @default.
• W2786251472 hasIssue "2" @default.
• W2786251472 hasLocation W27862514721 @default.
• W2786251472 hasOpenAccess W2786251472 @default.
• W2786251472 hasPrimaryLocation W27862514721 @default.
• W2786251472 hasRelatedWork W1968488846 @default.
• W2786251472 hasRelatedWork W1999604712 @default.
• W2786251472 hasRelatedWork W2009542694 @default.
• W2786251472 hasRelatedWork W2035655266 @default.
• W2786251472 hasRelatedWork W2054889009 @default.
• W2786251472 hasRelatedWork W206464674 @default.
• W2786251472 hasRelatedWork W2100223817 @default.
• W2786251472 hasRelatedWork W2128627228 @default.
• W2786251472 hasRelatedWork W2147735546 @default.
• W2786251472 hasRelatedWork W2160249016 @default.
• W2786251472 hasRelatedWork W2281844897 @default.
• W2786251472 hasRelatedWork W2362963531 @default.
• W2786251472 hasRelatedWork W2479828215 @default.
• W2786251472 hasRelatedWork W2483175787 @default.
• W2786251472 hasRelatedWork W2566760646 @default.
• W2786251472 hasRelatedWork W2611591204 @default.

• next