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• W2786356594 endingPage "154" @default.
• W2786356594 startingPage "147" @default.
• W2786356594 abstract "Four new ferulic acid derivatives ligusticumacid A-C (1-3) and ligusticumaldehyde A (4), one new dimer ligusticumacid D (5), and two novel 8-8' lignans ligusticumacid E-F (6-7) were isolated from the rhizome of Ligusticum chuanxiong Hort. In particular, compounds 1-2, 5 were rarely phenylpropanoid phenolic acid dimers through different polymerization action in natural products. Their structures were established using UV, IR, HRESIMS, NMR data. The absolute configurations of 3 was determined by quantum ECD calculation and 4, 6-7 were determined by the ECD exciton chirality method. In addition, all compounds were evaluated for their neuroprotective effects on human neuroblastoma SH-SY5Y cell injury induced by H2O2. Compound 2 had a moderate neuroprotective activity and 7 had a weak neuroprotective activity on human neuroblastoma SH-SY5Y cell injury induced by H2O2 respectively." @default.
• W2786356594 created "2018-02-23" @default.
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• W2786356594 date "2018-03-01" @default.
• W2786356594 modified "2023-09-23" @default.
• W2786356594 title "Ferulic acid derivatives from Ligusticum chuanxiong" @default.
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• W2786356594 doi "https://doi.org/10.1016/j.fitote.2018.01.005" @default.
• W2786356594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29358153" @default.
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