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- W2786380660 abstract "Background The epidemiology of Hirschsprung's disease (HSCR) in Bangladesh has never been studied. The aim of this study was to determine the epidemiological characteristics of HSCR in Bangladesh. Methods Data from fifty patients were collected prospectively from two hospitals in Chittagong, Bangladesh. Results The rate of consanguinity (16%) among parents of HSCR patients was higher than that of the general population (10%). Maternal age at the time of birth of the affected child was ≤30 years in all cases except one. No association was found between parents' occupation and HSCR. No patient was born preterm and only three patients (6%) had low birth weight. Nine patients (18%) had associated anomalies. We found coexistence of bilateral accessory tragi and ankyloglossia in one patient, and coexistence of rectal duplication cyst in another. Neither anomaly had been previously reported in HSCR patients. Conclusions Our study suggests that consanguinity might increase the risk of HSCR whereas advanced maternal age does not. HSCR patients were found more likely to born at term and with normal birth weight. The coexistence of HSCR with previously unreported anomalies highlights the diversity of conditions that can co-occur with HSCR. Levels of evidence IV" @default.
- W2786380660 created "2018-02-23" @default.
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- W2786380660 date "2018-10-01" @default.
- W2786380660 modified "2023-10-01" @default.
- W2786380660 title "Epidemiological characteristics of Hirschsprung’s disease (HSCR): Results of a case series of fifty patients from Bangladesh" @default.
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- W2786380660 doi "https://doi.org/10.1016/j.jpedsurg.2017.12.029" @default.
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