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• W2787217872 abstract "<ns4:p>The precise mechanism by which propofol enhances GABAergic transmission remains unclear, but much progress has been made regarding the underlying structural and dynamic mechanisms. Furthermore, it is now clear that propofol has additional molecular targets, many of which are functionally influenced at concentrations achieved clinically. Focusing primarily on molecular targets, this brief review attempts to summarize some of this recent progress while pointing out knowledge gaps and controversies. It is not intended to be comprehensive but rather to stimulate further thought, discussion, and study on the mechanisms by which propofol produces its pleiotropic effects.</ns4:p>" @default.
• W2787217872 created "2018-02-23" @default.
• W2787217872 creator A5011944482 @default.
• W2787217872 creator A5017520377 @default.
• W2787217872 date "2018-01-29" @default.
• W2787217872 modified "2023-09-24" @default.
• W2787217872 title "Recent progress on the molecular pharmacology of propofol" @default.
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• W2787217872 doi "https://doi.org/10.12688/f1000research.12502.1" @default.
• W2787217872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5791003" @default.
• W2787217872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29445451" @default.
• W2787217872 hasPublicationYear "2018" @default.
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