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• W2787224020 abstract "The purpose of this study was to investigate the virulent factors of Vibrio cholerae which caused an unprecedented large cholera outbreak in Ghana in 2014 and progressed into 2015, affected 28,975 people with 243 deaths. The V. cholerae isolates were identified to be the classical V. cholerae 01 biotype El Tor, serotype Ogawa, responsible for the large cholera outbreak in Ghana. These El Tor strains bear CtxAB and Tcp virulent genes, making the strains highly virulent. The strains also bear SXT transmissible element coding their resistance to antibiotics, causing high proportions of the strains to be multidrug resistant, with resistant proportions of 95, 90 and 75% to trimethoprim/sulfamethoxazole, ampicillin and ceftriaxone respectively. PFGE patterns indicated that the isolates clustered together with the same pattern and showed clusters similar to strains circulating in DR Congo, Cameroun, Ivory Coast and Togo. The strains carried virulence genes which facilitated the disease causation and spread. This is the first time these virulent genes were determined on the Ghanaian Vibrio strains." @default.
• W2787224020 created "2018-02-23" @default.
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• W2787224020 date "2018-01-18" @default.
• W2787224020 modified "2023-10-09" @default.
• W2787224020 title "Characterization of highly virulent multidrug resistant Vibrio cholerae isolated from a large cholera outbreak in Ghana" @default.
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• W2787224020 doi "https://doi.org/10.1186/s13104-017-2923-z" @default.
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