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- W2787334934 abstract "Continuous advances in molecular sequencing technologies now allow for inferring evolutionary trees (phylogenies) on supercomputers that comprise hundreds to thousands of species at the whole-transcriptome or whole-genome level. The phylogenetic likelihood function (PLF) consumes 90-95% of total execution time in such analyses and is therefore typically parallelized. Recently, the site repeats (SR) technique for substantially accelerating the PLF has been introduced. It identifies repeating patterns in parts of the likelihood computation and omits the respective redundant calculations to save time and space. However, the SR technique induces a parallel load imbalance. In this paper, we introduce a novel randomized data distribution algorithm to improve load balance (RDDA) for SR-based likelihood calculations. The algorithm is available as open-source code, induces minimal run-time overhead, and yields up to 25% run time improvements on empirical datasets and up to 50% for a synthetic, worst-case scenario. This improvement is substantial as current evolutionary data analyses may require tens of millions of core hours on supercomputer systems." @default.
- W2787334934 created "2018-02-23" @default.
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- W2787334934 date "2017-12-01" @default.
- W2787334934 modified "2023-10-17" @default.
- W2787334934 title "A Novel Heuristic for Data Distribution in Massively Parallel Phylogenetic Inference Using Site Repeats" @default.
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- W2787334934 doi "https://doi.org/10.1109/hpcc-smartcity-dss.2017.11" @default.
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