FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788166938> ?p ?o ?g. }

• W2788166938 endingPage "55" @default.
• W2788166938 startingPage "55" @default.
• W2788166938 abstract "Background: Sialorrhoea and drooling are disabling manifestations of different neurological disorders. The aim of this study was to evaluate the effects of botulinum neurotoxin type A (BoNT/A) injection on hypersalivation in 90 patients with neurological diseases of different aetiologies, and to define the minimum number of injected salivary glands to reduce sialorrhoea. Determining the minimum number of glands that need to be engaged in order to have a significant reduction in drooling may be very useful for establishing the minimum total dosage of BoNT/A that may be considered effective in the treatment of hypersalivation. Methods: Twenty-five mouse units (MU) of BoNT/A (onabotulinumtoxin A, Botox; Allergan, Irvine, CA, USA; 100 MU/2 mL, 0.9% saline; or incobotulinumtoxin A, Xeomin; Merz Pharma, Germany; 100 MU/2 mL, 0.9% saline) were percutaneously injected into the parotid (p) glands and/or submandibular (s) glands under ultrasound control. On this basis, patients were divided into three groups. In group A (30 patients), BoNT/A injections were performed into four glands; in group B (30 patients), into three glands, and in group C (30 patients), into two glands. Patients treated in three glands (group B) were divided into two subgroups based on the treated glands (2 p + 1 s = 15 patients; 2 s + 1 p = 15 patients). Similarly, patients being injected in two glands (group C) were subdivided into three groups (2 p = 10 patients; 1 p + 1 s = 10 patients; 2 s = 10 patients). In patients who were injected in three and two salivary glands, saline solution was injected into the remaining one and two glands, respectively. Assessments were performed at baseline and at 2 weeks after the injections. Results: BoNT/A significantly reduced sialorrhoea in 82 out of 90 patients. The effect was more evident in patients who had four glands injected than when three or two glands were injected. The injections into three glands were more effective than injections into two glands. Conclusions: Our results have shown that BoNT/A injections induced a significant reduction in sialorrhoea in most patients (91%). In addition, we demonstrated that sialorrhoea associated with different neurological diseases was better controlled when the number of treated glands was higher." @default.
• W2788166938 created "2018-03-06" @default.
• W2788166938 creator A5014543052 @default.
• W2788166938 creator A5061762196 @default.
• W2788166938 creator A5071409158 @default.
• W2788166938 creator A5071929575 @default.
• W2788166938 creator A5078322794 @default.
• W2788166938 creator A5082176816 @default.
• W2788166938 creator A5084493872 @default.
• W2788166938 creator A5088210421 @default.
• W2788166938 creator A5091621627 @default.
• W2788166938 date "2018-01-27" @default.
• W2788166938 modified "2023-09-26" @default.
• W2788166938 title "Botulinum Toxin A for Sialorrhoea Associated with Neurological Disorders: Evaluation of the Relationship between Effect of Treatment and the Number of Glands Treated" @default.
• W2788166938 cites W1970914282 @default.
• W2788166938 cites W1973382140 @default.
• W2788166938 cites W2022022245 @default.
• W2788166938 cites W2037995283 @default.
• W2788166938 cites W2045746960 @default.
• W2788166938 cites W2053318557 @default.
• W2788166938 cites W2098085833 @default.
• W2788166938 cites W2105512199 @default.
• W2788166938 cites W2136088547 @default.
• W2788166938 cites W2150658011 @default.
• W2788166938 cites W2157561159 @default.
• W2788166938 cites W2169183345 @default.
• W2788166938 cites W2409513625 @default.
• W2788166938 cites W2586931187 @default.
• W2788166938 cites W2608444233 @default.
• W2788166938 cites W3025547934 @default.
• W2788166938 cites W4241697158 @default.
• W2788166938 doi "https://doi.org/10.3390/toxins10020055" @default.
• W2788166938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5848156" @default.
• W2788166938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29382036" @default.
• W2788166938 hasPublicationYear "2018" @default.
• W2788166938 type Work @default.
• W2788166938 sameAs 2788166938 @default.
• W2788166938 citedByCount "27" @default.
• W2788166938 countsByYear W27881669382018 @default.
• W2788166938 countsByYear W27881669382019 @default.
• W2788166938 countsByYear W27881669382020 @default.
• W2788166938 countsByYear W27881669382021 @default.
• W2788166938 countsByYear W27881669382022 @default.
• W2788166938 countsByYear W27881669382023 @default.
• W2788166938 crossrefType "journal-article" @default.
• W2788166938 hasAuthorship W2788166938A5014543052 @default.
• W2788166938 hasAuthorship W2788166938A5061762196 @default.
• W2788166938 hasAuthorship W2788166938A5071409158 @default.
• W2788166938 hasAuthorship W2788166938A5071929575 @default.
• W2788166938 hasAuthorship W2788166938A5078322794 @default.
• W2788166938 hasAuthorship W2788166938A5082176816 @default.
• W2788166938 hasAuthorship W2788166938A5084493872 @default.
• W2788166938 hasAuthorship W2788166938A5088210421 @default.
• W2788166938 hasAuthorship W2788166938A5091621627 @default.
• W2788166938 hasBestOaLocation W27881669381 @default.
• W2788166938 hasConcept C126322002 @default.
• W2788166938 hasConcept C126894567 @default.
• W2788166938 hasConcept C141071460 @default.
• W2788166938 hasConcept C2776796639 @default.
• W2788166938 hasConcept C2777397205 @default.
• W2788166938 hasConcept C2777785397 @default.
• W2788166938 hasConcept C2778937882 @default.
• W2788166938 hasConcept C2779998641 @default.
• W2788166938 hasConcept C2909146933 @default.
• W2788166938 hasConcept C42219234 @default.
• W2788166938 hasConcept C71924100 @default.
• W2788166938 hasConcept C90924648 @default.
• W2788166938 hasConceptScore W2788166938C126322002 @default.
• W2788166938 hasConceptScore W2788166938C126894567 @default.
• W2788166938 hasConceptScore W2788166938C141071460 @default.
• W2788166938 hasConceptScore W2788166938C2776796639 @default.
• W2788166938 hasConceptScore W2788166938C2777397205 @default.
• W2788166938 hasConceptScore W2788166938C2777785397 @default.
• W2788166938 hasConceptScore W2788166938C2778937882 @default.
• W2788166938 hasConceptScore W2788166938C2779998641 @default.
• W2788166938 hasConceptScore W2788166938C2909146933 @default.
• W2788166938 hasConceptScore W2788166938C42219234 @default.
• W2788166938 hasConceptScore W2788166938C71924100 @default.
• W2788166938 hasConceptScore W2788166938C90924648 @default.
• W2788166938 hasIssue "2" @default.
• W2788166938 hasLocation W27881669381 @default.
• W2788166938 hasLocation W27881669382 @default.
• W2788166938 hasLocation W27881669383 @default.
• W2788166938 hasLocation W27881669384 @default.
• W2788166938 hasLocation W27881669385 @default.
• W2788166938 hasLocation W27881669386 @default.
• W2788166938 hasOpenAccess W2788166938 @default.
• W2788166938 hasPrimaryLocation W27881669381 @default.
• W2788166938 hasRelatedWork W138623618 @default.
• W2788166938 hasRelatedWork W2068248694 @default.
• W2788166938 hasRelatedWork W2094319290 @default.
• W2788166938 hasRelatedWork W2182549014 @default.
• W2788166938 hasRelatedWork W2909698033 @default.
• W2788166938 hasRelatedWork W2959553582 @default.
• W2788166938 hasRelatedWork W3172343877 @default.
• W2788166938 hasRelatedWork W4249696827 @default.
• W2788166938 hasRelatedWork W4367625655 @default.
• W2788166938 hasRelatedWork W4368360793 @default.

• next