FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788295044> ?p ?o ?g. }

• W2788295044 endingPage "190" @default.
• W2788295044 startingPage "185" @default.
• W2788295044 abstract "Synthetic gene circuits can be used to modify and control existing biological processes and thus e.g. increase drug yields. Currently their use is hampered by the, largely, trial and error approach used to design them. Lack of reliable quantitative dynamical models of genetic circuits e.g. prevents the use of well established control design methods. We aim toward creation of a pipeline for automated closed-loop identification of dynamic models of synthetically engineered genetic circuits in microorganisms. As a step towards this aim, we here study modelling of the input-output behaviour of the yGIL337 strain of S. cerevisiae. In this strain expression of the fluorescent reporter can be turned on by growing the yeast in galactose and off by glucose. We perform parameter estimation on a system of three ordinary differential equations of Michaelis-Menten type based on in vivo data from a microfluidic experiment by Fiore et al. (2013) after redoing the data preprocessing. The parameter estimation is done using AMIGO2–a state of the art Matlab toolbox for iterative identification of dynamical models. We show that the goodness-of-fit of our model is comparable to the five models proposed by Fiore et al. and we hypothesise that the system is an adaptive feedback system." @default.
• W2788295044 created "2018-03-06" @default.
• W2788295044 creator A5019651565 @default.
• W2788295044 creator A5039574191 @default.
• W2788295044 creator A5081262720 @default.
• W2788295044 creator A5083704013 @default.
• W2788295044 date "2018-01-01" @default.
• W2788295044 modified "2023-09-24" @default.
• W2788295044 title "Modelling of the GAL1 Genetic Circuit in Yeast Using Three Equations" @default.
• W2788295044 cites W1492559113 @default.
• W2788295044 cites W1964213976 @default.
• W2788295044 cites W1997275627 @default.
• W2788295044 cites W2004118592 @default.
• W2788295044 cites W2006137883 @default.
• W2788295044 cites W2068367947 @default.
• W2788295044 cites W2119435255 @default.
• W2788295044 cites W2136498480 @default.
• W2788295044 cites W2195266655 @default.
• W2788295044 cites W2472163094 @default.
• W2788295044 cites W2477731233 @default.
• W2788295044 cites W2593167972 @default.
• W2788295044 doi "https://doi.org/10.1016/j.ifacol.2018.09.297" @default.
• W2788295044 hasPublicationYear "2018" @default.
• W2788295044 type Work @default.
• W2788295044 sameAs 2788295044 @default.
• W2788295044 citedByCount "0" @default.
• W2788295044 crossrefType "journal-article" @default.
• W2788295044 hasAuthorship W2788295044A5019651565 @default.
• W2788295044 hasAuthorship W2788295044A5039574191 @default.
• W2788295044 hasAuthorship W2788295044A5081262720 @default.
• W2788295044 hasAuthorship W2788295044A5083704013 @default.
• W2788295044 hasBestOaLocation W27882950441 @default.
• W2788295044 hasConcept C111919701 @default.
• W2788295044 hasConcept C11413529 @default.
• W2788295044 hasConcept C116834253 @default.
• W2788295044 hasConcept C119247159 @default.
• W2788295044 hasConcept C124101348 @default.
• W2788295044 hasConcept C127413603 @default.
• W2788295044 hasConcept C133731056 @default.
• W2788295044 hasConcept C154945302 @default.
• W2788295044 hasConcept C167928553 @default.
• W2788295044 hasConcept C186060115 @default.
• W2788295044 hasConcept C191908910 @default.
• W2788295044 hasConcept C199360897 @default.
• W2788295044 hasConcept C2775924081 @default.
• W2788295044 hasConcept C2780009758 @default.
• W2788295044 hasConcept C2780365114 @default.
• W2788295044 hasConcept C28826006 @default.
• W2788295044 hasConcept C33923547 @default.
• W2788295044 hasConcept C34736171 @default.
• W2788295044 hasConcept C34862557 @default.
• W2788295044 hasConcept C41008148 @default.
• W2788295044 hasConcept C43521106 @default.
• W2788295044 hasConcept C47446073 @default.
• W2788295044 hasConcept C59822182 @default.
• W2788295044 hasConcept C70721500 @default.
• W2788295044 hasConcept C86803240 @default.
• W2788295044 hasConceptScore W2788295044C111919701 @default.
• W2788295044 hasConceptScore W2788295044C11413529 @default.
• W2788295044 hasConceptScore W2788295044C116834253 @default.
• W2788295044 hasConceptScore W2788295044C119247159 @default.
• W2788295044 hasConceptScore W2788295044C124101348 @default.
• W2788295044 hasConceptScore W2788295044C127413603 @default.
• W2788295044 hasConceptScore W2788295044C133731056 @default.
• W2788295044 hasConceptScore W2788295044C154945302 @default.
• W2788295044 hasConceptScore W2788295044C167928553 @default.
• W2788295044 hasConceptScore W2788295044C186060115 @default.
• W2788295044 hasConceptScore W2788295044C191908910 @default.
• W2788295044 hasConceptScore W2788295044C199360897 @default.
• W2788295044 hasConceptScore W2788295044C2775924081 @default.
• W2788295044 hasConceptScore W2788295044C2780009758 @default.
• W2788295044 hasConceptScore W2788295044C2780365114 @default.
• W2788295044 hasConceptScore W2788295044C28826006 @default.
• W2788295044 hasConceptScore W2788295044C33923547 @default.
• W2788295044 hasConceptScore W2788295044C34736171 @default.
• W2788295044 hasConceptScore W2788295044C34862557 @default.
• W2788295044 hasConceptScore W2788295044C41008148 @default.
• W2788295044 hasConceptScore W2788295044C43521106 @default.
• W2788295044 hasConceptScore W2788295044C47446073 @default.
• W2788295044 hasConceptScore W2788295044C59822182 @default.
• W2788295044 hasConceptScore W2788295044C70721500 @default.
• W2788295044 hasConceptScore W2788295044C86803240 @default.
• W2788295044 hasIssue "18" @default.
• W2788295044 hasLocation W27882950441 @default.
• W2788295044 hasLocation W27882950442 @default.
• W2788295044 hasOpenAccess W2788295044 @default.
• W2788295044 hasPrimaryLocation W27882950441 @default.
• W2788295044 hasRelatedWork W2379996991 @default.
• W2788295044 hasRelatedWork W2380889403 @default.
• W2788295044 hasRelatedWork W2543953258 @default.
• W2788295044 hasRelatedWork W2622473642 @default.
• W2788295044 hasRelatedWork W2736505776 @default.
• W2788295044 hasRelatedWork W2891840796 @default.
• W2788295044 hasRelatedWork W4225675085 @default.
• W2788295044 hasRelatedWork W4310540160 @default.
• W2788295044 hasRelatedWork W2102607626 @default.
• W2788295044 hasRelatedWork W79309541 @default.
• W2788295044 hasVolume "51" @default.

• next