Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788305004> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2788305004 abstract "Epidemiological studies link inhalation of particles to increased risk of cardiovascular disease. Inhaled particles may induce cardiovascular disease by several different mechanisms including translocation of particles to systemic circulation, activation of airway sensory nerves resulting in autonomic imbalance and particle-induced pulmonary inflammation and acute phase response. The acute phase response is the systemic response to acute and chronic inflammatory states caused by for example bacterial infection, virus infection, trauma and infarction. It is characterized by differential expression of ca. 50 different acute phase proteins including C-reactive protein and Serum amyloid A, which are the most differentially up-regulated acute phase response proteins. Blood levels of these two acute phase proteins are closely associated with risk of cardiovascular disease in epidemiological studies and SAA has been causally related to the formation of plaques in the aorta in animal studies. In a recent paper in Particle and Fibre Toxicology, Christian Monsé et al. provide evidence that inhalation of ZnO nanoparticles induces dose-dependent acute phase response in humans at dose levels well below the current mass-based occupational exposure limits in a number of countries including Germany, The Netherlands, UK, Sweden, Denmark and the US. Given the evidence suggesting a causal relationship between increased levels of serum amyloid A and atherosclerosis, the current results call for a re-evaluation of occupational exposure limits for a number of particle exposures including ZnO taking induction of acute phase response into account. Furthermore, it underscores cardiovascular disease as an occupational disease." @default.
- W2788305004 created "2018-03-06" @default.
- W2788305004 creator A5016513487 @default.
- W2788305004 creator A5060083262 @default.
- W2788305004 date "2018-02-12" @default.
- W2788305004 modified "2023-10-17" @default.
- W2788305004 title "Editorial: dose-dependent ZnO particle-induced acute phase response in humans warrants re-evaluation of occupational exposure limits for metal oxides" @default.
- W2788305004 cites W147019719 @default.
- W2788305004 cites W1483315176 @default.
- W2788305004 cites W1945002561 @default.
- W2788305004 cites W1986661009 @default.
- W2788305004 cites W2003929172 @default.
- W2788305004 cites W2005813970 @default.
- W2788305004 cites W2018750006 @default.
- W2788305004 cites W2058610272 @default.
- W2788305004 cites W2083559318 @default.
- W2788305004 cites W2104557054 @default.
- W2788305004 cites W2125921569 @default.
- W2788305004 cites W2145318781 @default.
- W2788305004 cites W2273742998 @default.
- W2788305004 cites W2275850934 @default.
- W2788305004 cites W2317184793 @default.
- W2788305004 cites W2506147233 @default.
- W2788305004 cites W2586756489 @default.
- W2788305004 cites W2604444379 @default.
- W2788305004 cites W2768752469 @default.
- W2788305004 cites W2770404658 @default.
- W2788305004 cites W2781549044 @default.
- W2788305004 cites W2794463609 @default.
- W2788305004 cites W4244359249 @default.
- W2788305004 doi "https://doi.org/10.1186/s12989-018-0247-3" @default.
- W2788305004 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5808423" @default.
- W2788305004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29429406" @default.
- W2788305004 hasPublicationYear "2018" @default.
- W2788305004 type Work @default.
- W2788305004 sameAs 2788305004 @default.
- W2788305004 citedByCount "18" @default.
- W2788305004 countsByYear W27883050042019 @default.
- W2788305004 countsByYear W27883050042020 @default.
- W2788305004 countsByYear W27883050042021 @default.
- W2788305004 countsByYear W27883050042022 @default.
- W2788305004 countsByYear W27883050042023 @default.
- W2788305004 crossrefType "journal-article" @default.
- W2788305004 hasAuthorship W2788305004A5016513487 @default.
- W2788305004 hasAuthorship W2788305004A5060083262 @default.
- W2788305004 hasBestOaLocation W27883050041 @default.
- W2788305004 hasConcept C126322002 @default.
- W2788305004 hasConcept C203014093 @default.
- W2788305004 hasConcept C2776914184 @default.
- W2788305004 hasConcept C2776954882 @default.
- W2788305004 hasConcept C2779134260 @default.
- W2788305004 hasConcept C2779777708 @default.
- W2788305004 hasConcept C2910060150 @default.
- W2788305004 hasConcept C42219234 @default.
- W2788305004 hasConcept C42407357 @default.
- W2788305004 hasConcept C500558357 @default.
- W2788305004 hasConcept C55359608 @default.
- W2788305004 hasConcept C57194454 @default.
- W2788305004 hasConcept C71924100 @default.
- W2788305004 hasConceptScore W2788305004C126322002 @default.
- W2788305004 hasConceptScore W2788305004C203014093 @default.
- W2788305004 hasConceptScore W2788305004C2776914184 @default.
- W2788305004 hasConceptScore W2788305004C2776954882 @default.
- W2788305004 hasConceptScore W2788305004C2779134260 @default.
- W2788305004 hasConceptScore W2788305004C2779777708 @default.
- W2788305004 hasConceptScore W2788305004C2910060150 @default.
- W2788305004 hasConceptScore W2788305004C42219234 @default.
- W2788305004 hasConceptScore W2788305004C42407357 @default.
- W2788305004 hasConceptScore W2788305004C500558357 @default.
- W2788305004 hasConceptScore W2788305004C55359608 @default.
- W2788305004 hasConceptScore W2788305004C57194454 @default.
- W2788305004 hasConceptScore W2788305004C71924100 @default.
- W2788305004 hasFunder F4320332999 @default.
- W2788305004 hasIssue "1" @default.
- W2788305004 hasLocation W27883050041 @default.
- W2788305004 hasLocation W27883050042 @default.
- W2788305004 hasLocation W27883050043 @default.
- W2788305004 hasLocation W27883050044 @default.
- W2788305004 hasLocation W27883050045 @default.
- W2788305004 hasLocation W27883050046 @default.
- W2788305004 hasLocation W27883050047 @default.
- W2788305004 hasLocation W27883050048 @default.
- W2788305004 hasLocation W27883050049 @default.
- W2788305004 hasOpenAccess W2788305004 @default.
- W2788305004 hasPrimaryLocation W27883050041 @default.
- W2788305004 hasRelatedWork W144846707 @default.
- W2788305004 hasRelatedWork W195777942 @default.
- W2788305004 hasRelatedWork W1998643872 @default.
- W2788305004 hasRelatedWork W2039518861 @default.
- W2788305004 hasRelatedWork W2072113749 @default.
- W2788305004 hasRelatedWork W2089441983 @default.
- W2788305004 hasRelatedWork W2242674825 @default.
- W2788305004 hasRelatedWork W2304657935 @default.
- W2788305004 hasRelatedWork W26521452 @default.
- W2788305004 hasRelatedWork W65600225 @default.
- W2788305004 hasVolume "15" @default.
- W2788305004 isParatext "false" @default.
- W2788305004 isRetracted "false" @default.
- W2788305004 magId "2788305004" @default.
- W2788305004 workType "editorial" @default.