FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788330907> ?p ?o ?g. }

• W2788330907 endingPage "675" @default.
• W2788330907 startingPage "667" @default.
• W2788330907 abstract "Background: Insulin-like growth factor-binding protein 7 (IGFBP7) has been found to be a tumor suppressor in several human cancers, but the role of IGFBP7 in gastric cancer has not yet been fully investigated. Herein, we examined the epigenetic downregulation of IGFBP7 expression in gastric cancer. Methods: Expression and methylation of IGFBP7 in gastric cancer cells and primary gastric cancer patients were determined using qRT-PCR, western blot, immunohistochemistry, and methylation specific-PCR, respectively. The effects of IGFBP7 on gastric cancer cells were investigated by various experimental conditions, such as proliferation, colony formation, apoptosis, invasion, and migration assay. Results: IGFBP7 methylation was inversely correlated with IGFBP7 expression in gastric cancer. Univariate and multivariate analysis showed that IGFBP7 expression and tumor stage were independent prognostic factors. IGFBP7 knockdown increased gastric cancer cell growth, invasion, and migration, whereas IGFBP7 overexpression in gastric cancer cells induced cell growth inhibition and apoptosis. Conclusion: Our data suggest that IGFBP7 functions as a tumor suppressor in gastric cancer via an epigenetic pathway." @default.
• W2788330907 created "2018-03-06" @default.
• W2788330907 creator A5006402804 @default.
• W2788330907 creator A5009075091 @default.
• W2788330907 creator A5021863030 @default.
• W2788330907 creator A5038890216 @default.
• W2788330907 creator A5072381269 @default.
• W2788330907 date "2018-03-27" @default.
• W2788330907 modified "2023-10-01" @default.
• W2788330907 title "Epigenetic Downregulation and Growth Inhibition of IGFBP7 in Gastric Cancer" @default.
• W2788330907 cites W1529830323 @default.
• W2788330907 cites W1979076069 @default.
• W2788330907 cites W1993415234 @default.
• W2788330907 cites W1993584752 @default.
• W2788330907 cites W2011173910 @default.
• W2788330907 cites W2025740942 @default.
• W2788330907 cites W2029765378 @default.
• W2788330907 cites W2032061143 @default.
• W2788330907 cites W2034148530 @default.
• W2788330907 cites W2044972168 @default.
• W2788330907 cites W2051839343 @default.
• W2788330907 cites W2063957550 @default.
• W2788330907 cites W2076145021 @default.
• W2788330907 cites W2092534798 @default.
• W2788330907 cites W2109600717 @default.
• W2788330907 cites W2122954559 @default.
• W2788330907 cites W2132545223 @default.
• W2788330907 cites W2139047590 @default.
• W2788330907 cites W2145479414 @default.
• W2788330907 cites W2158312983 @default.
• W2788330907 cites W2160835537 @default.
• W2788330907 cites W2167797644 @default.
• W2788330907 cites W2170029176 @default.
• W2788330907 cites W2181932845 @default.
• W2788330907 cites W92652176 @default.
• W2788330907 doi "https://doi.org/10.22034/apjcp.2018.19.3.667" @default.
• W2788330907 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5980839" @default.
• W2788330907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29580038" @default.
• W2788330907 hasPublicationYear "2018" @default.
• W2788330907 type Work @default.
• W2788330907 sameAs 2788330907 @default.
• W2788330907 citedByCount "9" @default.
• W2788330907 countsByYear W27883309072019 @default.
• W2788330907 countsByYear W27883309072020 @default.
• W2788330907 countsByYear W27883309072021 @default.
• W2788330907 countsByYear W27883309072022 @default.
• W2788330907 countsByYear W27883309072023 @default.
• W2788330907 crossrefType "journal-article" @default.
• W2788330907 hasAuthorship W2788330907A5006402804 @default.
• W2788330907 hasAuthorship W2788330907A5009075091 @default.
• W2788330907 hasAuthorship W2788330907A5021863030 @default.
• W2788330907 hasAuthorship W2788330907A5038890216 @default.
• W2788330907 hasAuthorship W2788330907A5072381269 @default.
• W2788330907 hasConcept C104317684 @default.
• W2788330907 hasConcept C121608353 @default.
• W2788330907 hasConcept C127561419 @default.
• W2788330907 hasConcept C173396325 @default.
• W2788330907 hasConcept C190283241 @default.
• W2788330907 hasConcept C2776415932 @default.
• W2788330907 hasConcept C33288867 @default.
• W2788330907 hasConcept C41091548 @default.
• W2788330907 hasConcept C502942594 @default.
• W2788330907 hasConcept C54355233 @default.
• W2788330907 hasConcept C55493867 @default.
• W2788330907 hasConcept C62112901 @default.
• W2788330907 hasConcept C86803240 @default.
• W2788330907 hasConcept C96232424 @default.
• W2788330907 hasConceptScore W2788330907C104317684 @default.
• W2788330907 hasConceptScore W2788330907C121608353 @default.
• W2788330907 hasConceptScore W2788330907C127561419 @default.
• W2788330907 hasConceptScore W2788330907C173396325 @default.
• W2788330907 hasConceptScore W2788330907C190283241 @default.
• W2788330907 hasConceptScore W2788330907C2776415932 @default.
• W2788330907 hasConceptScore W2788330907C33288867 @default.
• W2788330907 hasConceptScore W2788330907C41091548 @default.
• W2788330907 hasConceptScore W2788330907C502942594 @default.
• W2788330907 hasConceptScore W2788330907C54355233 @default.
• W2788330907 hasConceptScore W2788330907C55493867 @default.
• W2788330907 hasConceptScore W2788330907C62112901 @default.
• W2788330907 hasConceptScore W2788330907C86803240 @default.
• W2788330907 hasConceptScore W2788330907C96232424 @default.
• W2788330907 hasIssue "3" @default.
• W2788330907 hasLocation W27883309071 @default.
• W2788330907 hasOpenAccess W2788330907 @default.
• W2788330907 hasPrimaryLocation W27883309071 @default.
• W2788330907 hasRelatedWork W1983015622 @default.
• W2788330907 hasRelatedWork W2047885410 @default.
• W2788330907 hasRelatedWork W2494327966 @default.
• W2788330907 hasRelatedWork W2557443381 @default.
• W2788330907 hasRelatedWork W2793436007 @default.
• W2788330907 hasRelatedWork W3095403005 @default.
• W2788330907 hasRelatedWork W3206974297 @default.
• W2788330907 hasRelatedWork W3217378727 @default.
• W2788330907 hasRelatedWork W4235347117 @default.
• W2788330907 hasRelatedWork W4239667969 @default.
• W2788330907 hasVolume "19" @default.
• W2788330907 isParatext "false" @default.
• W2788330907 isRetracted "false" @default.

• next