Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788331193> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2788331193 endingPage "10" @default.
- W2788331193 startingPage "1" @default.
- W2788331193 abstract "The aim of the study was to investigate the effects and underlying mechanism of JKSQP in a rat model of asthma with kidney-yang deficiency (KYD). Materials and Methods . Hydrocortisone (HYD) was used to establish the rat model of KYD; rats were then sensitized and challenged with ovalbumin (OVA). JKSQP was administered to OVA-challenged rats, and the changes in signs and symptoms of KYD were observed. The leukocyte number and subpopulations in bronchoalveolar lavage fluid (BALF) were counted and the cells were stained with Wright–Giemsa dye. Serum adrenocorticotropic hormone (ACTH), corticosterone (CORT), corticotropin-releasing hormone (CRH), total immunoglobulin E (IgE), and OVA-specific IgE levels were determined using relevant enzyme-linked immunosorbent assays (ELISA) kits. Results . JKSQP not only reversed the phenomenon of KYD but also significantly inhibited the number of leukocyte and eosinophils in the BALF, increasing the level of interferon (IFN)- γ and decreasing the levels of interleukin-4 (IL-4) and IgE in the serum compared with the OVA-challenged groups. Conclusions . Taken together, the antiasthma effects of JKSQP were likely mediated by the enhancement of the function of the hypothalamic-pituitary-adrenal axis and the reversal of T helper 1/2 imbalance." @default.
- W2788331193 created "2018-03-06" @default.
- W2788331193 creator A5013899142 @default.
- W2788331193 creator A5016114421 @default.
- W2788331193 creator A5036505077 @default.
- W2788331193 creator A5055433201 @default.
- W2788331193 creator A5056817088 @default.
- W2788331193 creator A5065363792 @default.
- W2788331193 creator A5078727198 @default.
- W2788331193 date "2018-01-01" @default.
- W2788331193 modified "2023-10-17" @default.
- W2788331193 title "Jinkui Shenqi Pills Ameliorate Asthma with “Kidney Yang Deficiency” by Enhancing the Function of the Hypothalamic-Pituitary-Adrenal Axis to Regulate T Helper 1/2 Imbalance" @default.
- W2788331193 cites W1964495647 @default.
- W2788331193 cites W1967784722 @default.
- W2788331193 cites W1998988595 @default.
- W2788331193 cites W2005377557 @default.
- W2788331193 cites W2010309260 @default.
- W2788331193 cites W2029044572 @default.
- W2788331193 cites W2036571139 @default.
- W2788331193 cites W2037855125 @default.
- W2788331193 cites W2039242768 @default.
- W2788331193 cites W2046710217 @default.
- W2788331193 cites W2100339635 @default.
- W2788331193 cites W2106520852 @default.
- W2788331193 cites W2112302502 @default.
- W2788331193 cites W2113807240 @default.
- W2788331193 cites W2129784941 @default.
- W2788331193 cites W2134541271 @default.
- W2788331193 cites W2143739257 @default.
- W2788331193 cites W2221603408 @default.
- W2788331193 cites W2408216116 @default.
- W2788331193 cites W2411891095 @default.
- W2788331193 cites W374736179 @default.
- W2788331193 doi "https://doi.org/10.1155/2018/7253240" @default.
- W2788331193 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5822917" @default.
- W2788331193 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29576798" @default.
- W2788331193 hasPublicationYear "2018" @default.
- W2788331193 type Work @default.
- W2788331193 sameAs 2788331193 @default.
- W2788331193 citedByCount "13" @default.
- W2788331193 countsByYear W27883311932018 @default.
- W2788331193 countsByYear W27883311932020 @default.
- W2788331193 countsByYear W27883311932021 @default.
- W2788331193 countsByYear W27883311932022 @default.
- W2788331193 countsByYear W27883311932023 @default.
- W2788331193 crossrefType "journal-article" @default.
- W2788331193 hasAuthorship W2788331193A5013899142 @default.
- W2788331193 hasAuthorship W2788331193A5016114421 @default.
- W2788331193 hasAuthorship W2788331193A5036505077 @default.
- W2788331193 hasAuthorship W2788331193A5055433201 @default.
- W2788331193 hasAuthorship W2788331193A5056817088 @default.
- W2788331193 hasAuthorship W2788331193A5065363792 @default.
- W2788331193 hasAuthorship W2788331193A5078727198 @default.
- W2788331193 hasBestOaLocation W27883311931 @default.
- W2788331193 hasConcept C126322002 @default.
- W2788331193 hasConcept C134018914 @default.
- W2788331193 hasConcept C141105273 @default.
- W2788331193 hasConcept C159654299 @default.
- W2788331193 hasConcept C203014093 @default.
- W2788331193 hasConcept C2776946954 @default.
- W2788331193 hasConcept C2780352252 @default.
- W2788331193 hasConcept C2780546910 @default.
- W2788331193 hasConcept C71315377 @default.
- W2788331193 hasConcept C71924100 @default.
- W2788331193 hasConcept C8891405 @default.
- W2788331193 hasConceptScore W2788331193C126322002 @default.
- W2788331193 hasConceptScore W2788331193C134018914 @default.
- W2788331193 hasConceptScore W2788331193C141105273 @default.
- W2788331193 hasConceptScore W2788331193C159654299 @default.
- W2788331193 hasConceptScore W2788331193C203014093 @default.
- W2788331193 hasConceptScore W2788331193C2776946954 @default.
- W2788331193 hasConceptScore W2788331193C2780352252 @default.
- W2788331193 hasConceptScore W2788331193C2780546910 @default.
- W2788331193 hasConceptScore W2788331193C71315377 @default.
- W2788331193 hasConceptScore W2788331193C71924100 @default.
- W2788331193 hasConceptScore W2788331193C8891405 @default.
- W2788331193 hasFunder F4320321001 @default.
- W2788331193 hasLocation W27883311931 @default.
- W2788331193 hasLocation W27883311932 @default.
- W2788331193 hasLocation W27883311933 @default.
- W2788331193 hasLocation W27883311934 @default.
- W2788331193 hasOpenAccess W2788331193 @default.
- W2788331193 hasPrimaryLocation W27883311931 @default.
- W2788331193 hasRelatedWork W156620311 @default.
- W2788331193 hasRelatedWork W1973859193 @default.
- W2788331193 hasRelatedWork W1983909774 @default.
- W2788331193 hasRelatedWork W2011741469 @default.
- W2788331193 hasRelatedWork W2061601189 @default.
- W2788331193 hasRelatedWork W2138076272 @default.
- W2788331193 hasRelatedWork W2213125823 @default.
- W2788331193 hasRelatedWork W2282896171 @default.
- W2788331193 hasRelatedWork W2413517451 @default.
- W2788331193 hasRelatedWork W2323197485 @default.
- W2788331193 hasVolume "2018" @default.
- W2788331193 isParatext "false" @default.
- W2788331193 isRetracted "false" @default.
- W2788331193 magId "2788331193" @default.
- W2788331193 workType "article" @default.