FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788365280> ?p ?o ?g. }

• W2788365280 endingPage "3935" @default.
• W2788365280 startingPage "3928" @default.
• W2788365280 abstract "Thanks to comprehensive and unbiased sampling of all precursor ions, the interest to move toward bottom-up proteomic with data-independent acquisition (DIA) is continuously growing. DIA offers precision and reproducibility performances comparable to true targeted methods but has the advantage of enabling retrospective data testing with the hypothetical presence of new proteins of interest. Nonetheless, the chimeric nature of DIA MS/MS spectra inherent to concomitant transmission of a multiplicity of precursor ions makes the confident identification of peptides often challenging, even with spectral library-based extraction strategy. The introduction of specificity at the fragmentation step upon ultraviolet or visible laser-induced dissociation (LID) range targeting only the subset of cysteine-containing peptides (Cys-peptide) has been proposed as an option to streamline and reduce the search space. Here, we describe the first coupling between DIA and visible LID at 473 nm to test for the presence of Cys-peptides with a peptide-centric approach. As a test run, a spectral library was built for a pool of Cys-synthetic peptides used as surrogates of human kinases (1 peptide per protein). By extracting ion chromatograms of query standard and kinase peptides spiked at different concentration levels in an Escherichia coli proteome lysate, DIA-LID demonstrates a dynamic range of detection of at least 3 decades and coefficients of precision better than 20%. Finally, the spectral library was used to search for endogenous kinases in human cellular extract." @default.
• W2788365280 created "2018-03-06" @default.
• W2788365280 creator A5006585346 @default.
• W2788365280 creator A5019603042 @default.
• W2788365280 creator A5058411516 @default.
• W2788365280 creator A5066348013 @default.
• W2788365280 creator A5083224434 @default.
• W2788365280 creator A5084679775 @default.
• W2788365280 date "2018-02-21" @default.
• W2788365280 modified "2023-10-14" @default.
• W2788365280 title "Data-Independent Acquisition Coupled to Visible Laser-Induced Dissociation at 473 nm (DIA-LID) for Peptide-Centric Specific Analysis of Cysteine-Containing Peptide Subset" @default.
• W2788365280 cites W1766070281 @default.
• W2788365280 cites W1964328150 @default.
• W2788365280 cites W1966310442 @default.
• W2788365280 cites W1974590646 @default.
• W2788365280 cites W1980933881 @default.
• W2788365280 cites W1981593914 @default.
• W2788365280 cites W1986758424 @default.
• W2788365280 cites W1995478292 @default.
• W2788365280 cites W2027222148 @default.
• W2788365280 cites W2029901299 @default.
• W2788365280 cites W2033047611 @default.
• W2788365280 cites W2035092214 @default.
• W2788365280 cites W2036665190 @default.
• W2788365280 cites W2063420942 @default.
• W2788365280 cites W2079843936 @default.
• W2788365280 cites W2091528007 @default.
• W2788365280 cites W2094094286 @default.
• W2788365280 cites W2123735699 @default.
• W2788365280 cites W2141091417 @default.
• W2788365280 cites W2142205442 @default.
• W2788365280 cites W2145773808 @default.
• W2788365280 cites W2165635465 @default.
• W2788365280 cites W2260130220 @default.
• W2788365280 cites W2312264339 @default.
• W2788365280 cites W2319925295 @default.
• W2788365280 cites W2320731392 @default.
• W2788365280 cites W2331830394 @default.
• W2788365280 cites W2415842257 @default.
• W2788365280 cites W2433293649 @default.
• W2788365280 cites W2488048472 @default.
• W2788365280 cites W2537132940 @default.
• W2788365280 cites W2734649337 @default.
• W2788365280 cites W2753113281 @default.
• W2788365280 cites W2766172487 @default.
• W2788365280 cites W2950557897 @default.
• W2788365280 doi "https://doi.org/10.1021/acs.analchem.7b04821" @default.
• W2788365280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29465226" @default.
• W2788365280 hasPublicationYear "2018" @default.
• W2788365280 type Work @default.
• W2788365280 sameAs 2788365280 @default.
• W2788365280 citedByCount "7" @default.
• W2788365280 countsByYear W27883652802018 @default.
• W2788365280 countsByYear W27883652802019 @default.
• W2788365280 countsByYear W27883652802020 @default.
• W2788365280 countsByYear W27883652802022 @default.
• W2788365280 countsByYear W27883652802023 @default.
• W2788365280 crossrefType "journal-article" @default.
• W2788365280 hasAuthorship W2788365280A5006585346 @default.
• W2788365280 hasAuthorship W2788365280A5019603042 @default.
• W2788365280 hasAuthorship W2788365280A5058411516 @default.
• W2788365280 hasAuthorship W2788365280A5066348013 @default.
• W2788365280 hasAuthorship W2788365280A5083224434 @default.
• W2788365280 hasAuthorship W2788365280A5084679775 @default.
• W2788365280 hasBestOaLocation W27883652802 @default.
• W2788365280 hasConcept C102931765 @default.
• W2788365280 hasConcept C104317684 @default.
• W2788365280 hasConcept C147789679 @default.
• W2788365280 hasConcept C162356407 @default.
• W2788365280 hasConcept C167625842 @default.
• W2788365280 hasConcept C181199279 @default.
• W2788365280 hasConcept C185592680 @default.
• W2788365280 hasConcept C21951064 @default.
• W2788365280 hasConcept C2776471321 @default.
• W2788365280 hasConcept C2779201268 @default.
• W2788365280 hasConcept C2779281246 @default.
• W2788365280 hasConcept C31827203 @default.
• W2788365280 hasConcept C43617362 @default.
• W2788365280 hasConcept C55493867 @default.
• W2788365280 hasConcept C70721500 @default.
• W2788365280 hasConcept C86803240 @default.
• W2788365280 hasConceptScore W2788365280C102931765 @default.
• W2788365280 hasConceptScore W2788365280C104317684 @default.
• W2788365280 hasConceptScore W2788365280C147789679 @default.
• W2788365280 hasConceptScore W2788365280C162356407 @default.
• W2788365280 hasConceptScore W2788365280C167625842 @default.
• W2788365280 hasConceptScore W2788365280C181199279 @default.
• W2788365280 hasConceptScore W2788365280C185592680 @default.
• W2788365280 hasConceptScore W2788365280C21951064 @default.
• W2788365280 hasConceptScore W2788365280C2776471321 @default.
• W2788365280 hasConceptScore W2788365280C2779201268 @default.
• W2788365280 hasConceptScore W2788365280C2779281246 @default.
• W2788365280 hasConceptScore W2788365280C31827203 @default.
• W2788365280 hasConceptScore W2788365280C43617362 @default.
• W2788365280 hasConceptScore W2788365280C55493867 @default.
• W2788365280 hasConceptScore W2788365280C70721500 @default.
• W2788365280 hasConceptScore W2788365280C86803240 @default.
• W2788365280 hasFunder F4320320883 @default.

• next