FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788406964> ?p ?o ?g. }

• W2788406964 endingPage "91" @default.
• W2788406964 startingPage "88" @default.
• W2788406964 abstract "Recent research has outlined that Dimethyl Fumarate (DMF) functions as a gene regulator via multiple pathways, critical among which is the NRF2 cytoprotective cascade. PARK7/DJ-1 is a multifunctional protein that acts as a redox sensor and effector of multiple cytoprotective pathways, including NRF2. Specifically, it prevents the association of NRF2 with its inhibitor KEAP1, allowing NRF2 to enter the nucleus and mediate cytoprotective and antioxidant cascades. It is our hypothesis that while the NRF2-KEAP1 inhibitory complex is reported the main pharmacological target for DMF's NRF dependent functions, no study to date has explored the effects of DMF on DJ-1's expression, and vice-versa, the possibility of a regulatory inadequacy in the upstream, oxidant-responsive DJ-1 activator of the NRF2 cascade." @default.
• W2788406964 created "2018-03-06" @default.
• W2788406964 creator A5050511194 @default.
• W2788406964 creator A5076899702 @default.
• W2788406964 creator A5083460546 @default.
• W2788406964 date "2018-04-01" @default.
• W2788406964 modified "2023-09-30" @default.
• W2788406964 title "The putative interplay between DJ-1/NRF2 and Dimethyl Fumarate: A potentially important pharmacological target" @default.
• W2788406964 cites W1965957522 @default.
• W2788406964 cites W1972266008 @default.
• W2788406964 cites W2004029870 @default.
• W2788406964 cites W2007654892 @default.
• W2788406964 cites W2008817720 @default.
• W2788406964 cites W2011766574 @default.
• W2788406964 cites W2012112859 @default.
• W2788406964 cites W2020113298 @default.
• W2788406964 cites W2022355305 @default.
• W2788406964 cites W2023725391 @default.
• W2788406964 cites W2026425527 @default.
• W2788406964 cites W2030830834 @default.
• W2788406964 cites W2055537050 @default.
• W2788406964 cites W2057690226 @default.
• W2788406964 cites W2058035958 @default.
• W2788406964 cites W2071261783 @default.
• W2788406964 cites W2088026970 @default.
• W2788406964 cites W2088211150 @default.
• W2788406964 cites W2103843996 @default.
• W2788406964 cites W2123766360 @default.
• W2788406964 cites W2126990175 @default.
• W2788406964 cites W2127921493 @default.
• W2788406964 cites W2129350151 @default.
• W2788406964 cites W2132444785 @default.
• W2788406964 cites W2138884788 @default.
• W2788406964 cites W2165658124 @default.
• W2788406964 cites W2167722995 @default.
• W2788406964 cites W2268807381 @default.
• W2788406964 cites W2277439873 @default.
• W2788406964 cites W2295683914 @default.
• W2788406964 cites W2324103961 @default.
• W2788406964 cites W2341018404 @default.
• W2788406964 cites W2345236041 @default.
• W2788406964 cites W2412164637 @default.
• W2788406964 cites W2495156620 @default.
• W2788406964 cites W2569171734 @default.
• W2788406964 doi "https://doi.org/10.1016/j.msard.2018.02.027" @default.
• W2788406964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29529529" @default.
• W2788406964 hasPublicationYear "2018" @default.
• W2788406964 type Work @default.
• W2788406964 sameAs 2788406964 @default.
• W2788406964 citedByCount "11" @default.
• W2788406964 countsByYear W27884069642018 @default.
• W2788406964 countsByYear W27884069642019 @default.
• W2788406964 countsByYear W27884069642020 @default.
• W2788406964 countsByYear W27884069642021 @default.
• W2788406964 countsByYear W27884069642022 @default.
• W2788406964 countsByYear W27884069642023 @default.
• W2788406964 crossrefType "journal-article" @default.
• W2788406964 hasAuthorship W2788406964A5050511194 @default.
• W2788406964 hasAuthorship W2788406964A5076899702 @default.
• W2788406964 hasAuthorship W2788406964A5083460546 @default.
• W2788406964 hasConcept C104317684 @default.
• W2788406964 hasConcept C185592680 @default.
• W2788406964 hasConcept C203014093 @default.
• W2788406964 hasConcept C2776529522 @default.
• W2788406964 hasConcept C2776819417 @default.
• W2788406964 hasConcept C2780640218 @default.
• W2788406964 hasConcept C34146451 @default.
• W2788406964 hasConcept C43617362 @default.
• W2788406964 hasConcept C51785407 @default.
• W2788406964 hasConcept C55493867 @default.
• W2788406964 hasConcept C6929976 @default.
• W2788406964 hasConcept C86339819 @default.
• W2788406964 hasConcept C86803240 @default.
• W2788406964 hasConcept C88045685 @default.
• W2788406964 hasConcept C95444343 @default.
• W2788406964 hasConceptScore W2788406964C104317684 @default.
• W2788406964 hasConceptScore W2788406964C185592680 @default.
• W2788406964 hasConceptScore W2788406964C203014093 @default.
• W2788406964 hasConceptScore W2788406964C2776529522 @default.
• W2788406964 hasConceptScore W2788406964C2776819417 @default.
• W2788406964 hasConceptScore W2788406964C2780640218 @default.
• W2788406964 hasConceptScore W2788406964C34146451 @default.
• W2788406964 hasConceptScore W2788406964C43617362 @default.
• W2788406964 hasConceptScore W2788406964C51785407 @default.
• W2788406964 hasConceptScore W2788406964C55493867 @default.
• W2788406964 hasConceptScore W2788406964C6929976 @default.
• W2788406964 hasConceptScore W2788406964C86339819 @default.
• W2788406964 hasConceptScore W2788406964C86803240 @default.
• W2788406964 hasConceptScore W2788406964C88045685 @default.
• W2788406964 hasConceptScore W2788406964C95444343 @default.
• W2788406964 hasLocation W27884069641 @default.
• W2788406964 hasLocation W27884069642 @default.
• W2788406964 hasOpenAccess W2788406964 @default.
• W2788406964 hasPrimaryLocation W27884069641 @default.
• W2788406964 hasRelatedWork W1609345078 @default.
• W2788406964 hasRelatedWork W1975844164 @default.
• W2788406964 hasRelatedWork W2120669780 @default.
• W2788406964 hasRelatedWork W2129350151 @default.

• next