Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788457030> ?p ?o ?g. }
- W2788457030 abstract "Background. In the last years, levothyroxine (LT4) has been commercialized also in liquid formulation which is less sensitive to the factors known to reduce the absorption of tablet LT4. To date, there is not robust information that liquid LT4 can improve pharmacologic thyroid homeostasis of patients with reduced efficacy of tablet LT4. This analysis aimed at achieving solid evidence that switching thyroxine treatment from tablet to liquid preparation improves patients’ TSH levels. Methods. The search was performed in PubMed/MEDLINE and Scopus database based on the terms “thyroid”, “levothyroxine” and “liquid”, and updated until September 25, 2017. Studies were included only if they described patients with suboptimal TSH on tablet LT4, subsequently switched to liquid LT4. Results. The literature search retrieved 462 articles and six were finally included. The pooled mean difference of TSH value between tablet and liquid LT4 was 4.23 mIU/L (95%CI from 3.69 to 4.77). Mild heterogeneity was found (I2 60%). Overall mean difference of TSH was significant (p<0.0001). Conclusions. The present meta-analysis showed that patients with suboptimal TSH on tablet LT4 can have a significantly improved TSH by switching to liquid LT4 formulation at unchanged dose." @default.
- W2788457030 created "2018-03-06" @default.
- W2788457030 creator A5023653747 @default.
- W2788457030 creator A5025958746 @default.
- W2788457030 creator A5038828476 @default.
- W2788457030 creator A5057155509 @default.
- W2788457030 creator A5057411375 @default.
- W2788457030 creator A5067499616 @default.
- W2788457030 creator A5081971753 @default.
- W2788457030 date "2018-01-26" @default.
- W2788457030 modified "2023-10-13" @default.
- W2788457030 title "Levothyroxine Therapy: Changes of TSH Levels by Switching Patients from Tablet to Liquid Formulation. A Systematic Review and Meta-Analysis" @default.
- W2788457030 cites W145192667 @default.
- W2788457030 cites W1747119434 @default.
- W2788457030 cites W1965978069 @default.
- W2788457030 cites W1966108960 @default.
- W2788457030 cites W1970238764 @default.
- W2788457030 cites W1976679490 @default.
- W2788457030 cites W2043009591 @default.
- W2788457030 cites W2043015190 @default.
- W2788457030 cites W2050849210 @default.
- W2788457030 cites W2055123669 @default.
- W2788457030 cites W2067997413 @default.
- W2788457030 cites W2073346341 @default.
- W2788457030 cites W2074798205 @default.
- W2788457030 cites W2082981844 @default.
- W2788457030 cites W2085724507 @default.
- W2788457030 cites W2100948030 @default.
- W2788457030 cites W2100955331 @default.
- W2788457030 cites W2175978095 @default.
- W2788457030 cites W2188527353 @default.
- W2788457030 cites W2206282986 @default.
- W2788457030 cites W2294264784 @default.
- W2788457030 cites W2330783135 @default.
- W2788457030 cites W2411466813 @default.
- W2788457030 cites W2411859531 @default.
- W2788457030 cites W2431769739 @default.
- W2788457030 cites W2465907210 @default.
- W2788457030 cites W2478134244 @default.
- W2788457030 cites W2517112262 @default.
- W2788457030 cites W2542623532 @default.
- W2788457030 cites W2556149235 @default.
- W2788457030 cites W2566552250 @default.
- W2788457030 cites W2582860879 @default.
- W2788457030 cites W2583376499 @default.
- W2788457030 cites W2584823620 @default.
- W2788457030 cites W2585025665 @default.
- W2788457030 cites W2607985302 @default.
- W2788457030 cites W2734775767 @default.
- W2788457030 cites W2736290845 @default.
- W2788457030 doi "https://doi.org/10.3389/fendo.2018.00010" @default.
- W2788457030 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5790785" @default.
- W2788457030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29434573" @default.
- W2788457030 hasPublicationYear "2018" @default.
- W2788457030 type Work @default.
- W2788457030 sameAs 2788457030 @default.
- W2788457030 citedByCount "41" @default.
- W2788457030 countsByYear W27884570302018 @default.
- W2788457030 countsByYear W27884570302019 @default.
- W2788457030 countsByYear W27884570302020 @default.
- W2788457030 countsByYear W27884570302021 @default.
- W2788457030 countsByYear W27884570302022 @default.
- W2788457030 countsByYear W27884570302023 @default.
- W2788457030 crossrefType "journal-article" @default.
- W2788457030 hasAuthorship W2788457030A5023653747 @default.
- W2788457030 hasAuthorship W2788457030A5025958746 @default.
- W2788457030 hasAuthorship W2788457030A5038828476 @default.
- W2788457030 hasAuthorship W2788457030A5057155509 @default.
- W2788457030 hasAuthorship W2788457030A5057411375 @default.
- W2788457030 hasAuthorship W2788457030A5067499616 @default.
- W2788457030 hasAuthorship W2788457030A5081971753 @default.
- W2788457030 hasBestOaLocation W27884570301 @default.
- W2788457030 hasConcept C126322002 @default.
- W2788457030 hasConcept C2775883008 @default.
- W2788457030 hasConcept C526584372 @default.
- W2788457030 hasConcept C71924100 @default.
- W2788457030 hasConcept C95190672 @default.
- W2788457030 hasConceptScore W2788457030C126322002 @default.
- W2788457030 hasConceptScore W2788457030C2775883008 @default.
- W2788457030 hasConceptScore W2788457030C526584372 @default.
- W2788457030 hasConceptScore W2788457030C71924100 @default.
- W2788457030 hasConceptScore W2788457030C95190672 @default.
- W2788457030 hasLocation W27884570301 @default.
- W2788457030 hasLocation W27884570302 @default.
- W2788457030 hasLocation W27884570303 @default.
- W2788457030 hasLocation W27884570304 @default.
- W2788457030 hasLocation W27884570305 @default.
- W2788457030 hasLocation W27884570306 @default.
- W2788457030 hasLocation W27884570307 @default.
- W2788457030 hasOpenAccess W2788457030 @default.
- W2788457030 hasPrimaryLocation W27884570301 @default.
- W2788457030 hasRelatedWork W2088199680 @default.
- W2788457030 hasRelatedWork W2123855214 @default.
- W2788457030 hasRelatedWork W2138881808 @default.
- W2788457030 hasRelatedWork W2143093800 @default.
- W2788457030 hasRelatedWork W2355190445 @default.
- W2788457030 hasRelatedWork W2748952813 @default.
- W2788457030 hasRelatedWork W27703131 @default.
- W2788457030 hasRelatedWork W2899084033 @default.
- W2788457030 hasRelatedWork W4233758895 @default.