Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788558380> ?p ?o ?g. }
- W2788558380 endingPage "2933" @default.
- W2788558380 startingPage "2925" @default.
- W2788558380 abstract "Natural halloysite (Al2Si2O5(OH)4· nH2O) nanotubes (HNT) are clay materials with hollow tubular structure and are widely applied in many fields. Many in vitro studies indicate that HNTs exhibit a high level of biocompatibility; however, the in vivo toxicity of HNTs remains unclear. In this study, the biodistribution and pulmonary toxicity of the purified HNTs in mice were investigated after intragastric administration for 30 days. HNTs have high stability in biological conditions. Oral administration of HNTs caused significant Al accumulation predominantly in the lung with relative slight effects on Si biodistribution. Oral administration of HNTs stimulated the growth of the mice at low dose (5 mg/kg BW) with no pulmonary toxicity but inhibited the mouse growth and resulted in oxidative stress and inflammation in lung at high dose (50 mg/kg BW). In addition, oral HNTs at high dose could be absorbed from the gastrointestinal tract and deposited in lung and could also induce pulmonary fibrosis." @default.
- W2788558380 created "2018-03-06" @default.
- W2788558380 creator A5005048207 @default.
- W2788558380 creator A5014995589 @default.
- W2788558380 creator A5057276610 @default.
- W2788558380 creator A5059625822 @default.
- W2788558380 creator A5059890337 @default.
- W2788558380 creator A5074911294 @default.
- W2788558380 date "2018-02-22" @default.
- W2788558380 modified "2023-10-15" @default.
- W2788558380 title "Halloysite Nanotubes-Induced Al Accumulation and Fibrotic Response in Lung of Mice after 30-Day Repeated Oral Administration" @default.
- W2788558380 cites W1533162556 @default.
- W2788558380 cites W1553463080 @default.
- W2788558380 cites W1580081607 @default.
- W2788558380 cites W1594909608 @default.
- W2788558380 cites W1959863571 @default.
- W2788558380 cites W1968417558 @default.
- W2788558380 cites W1975133899 @default.
- W2788558380 cites W1977929750 @default.
- W2788558380 cites W1978347760 @default.
- W2788558380 cites W1979156208 @default.
- W2788558380 cites W1982566906 @default.
- W2788558380 cites W2006409853 @default.
- W2788558380 cites W2023330798 @default.
- W2788558380 cites W2027150146 @default.
- W2788558380 cites W2030813809 @default.
- W2788558380 cites W2032884099 @default.
- W2788558380 cites W2038897622 @default.
- W2788558380 cites W2045080998 @default.
- W2788558380 cites W2046326845 @default.
- W2788558380 cites W2058149852 @default.
- W2788558380 cites W2062384458 @default.
- W2788558380 cites W2073320012 @default.
- W2788558380 cites W2078311490 @default.
- W2788558380 cites W2096199899 @default.
- W2788558380 cites W2104808062 @default.
- W2788558380 cites W2109917555 @default.
- W2788558380 cites W2135998924 @default.
- W2788558380 cites W2144205081 @default.
- W2788558380 cites W2147239803 @default.
- W2788558380 cites W2148674446 @default.
- W2788558380 cites W2157219193 @default.
- W2788558380 cites W2158392938 @default.
- W2788558380 cites W2159465368 @default.
- W2788558380 cites W2167654095 @default.
- W2788558380 cites W2168808200 @default.
- W2788558380 cites W2180082248 @default.
- W2788558380 cites W2181523551 @default.
- W2788558380 cites W2238399186 @default.
- W2788558380 cites W2265511202 @default.
- W2788558380 cites W2269012808 @default.
- W2788558380 cites W2280109790 @default.
- W2788558380 cites W2288337015 @default.
- W2788558380 cites W2295496912 @default.
- W2788558380 cites W2324975591 @default.
- W2788558380 cites W2464651600 @default.
- W2788558380 cites W2514069778 @default.
- W2788558380 cites W2545032860 @default.
- W2788558380 cites W2574370058 @default.
- W2788558380 cites W2592294015 @default.
- W2788558380 cites W2593667505 @default.
- W2788558380 cites W2603511387 @default.
- W2788558380 cites W2732835727 @default.
- W2788558380 cites W855002424 @default.
- W2788558380 cites W869804202 @default.
- W2788558380 doi "https://doi.org/10.1021/acs.jafc.7b04615" @default.
- W2788558380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29470912" @default.
- W2788558380 hasPublicationYear "2018" @default.
- W2788558380 type Work @default.
- W2788558380 sameAs 2788558380 @default.
- W2788558380 citedByCount "48" @default.
- W2788558380 countsByYear W27885583802018 @default.
- W2788558380 countsByYear W27885583802019 @default.
- W2788558380 countsByYear W27885583802020 @default.
- W2788558380 countsByYear W27885583802021 @default.
- W2788558380 countsByYear W27885583802022 @default.
- W2788558380 countsByYear W27885583802023 @default.
- W2788558380 crossrefType "journal-article" @default.
- W2788558380 hasAuthorship W2788558380A5005048207 @default.
- W2788558380 hasAuthorship W2788558380A5014995589 @default.
- W2788558380 hasAuthorship W2788558380A5057276610 @default.
- W2788558380 hasAuthorship W2788558380A5059625822 @default.
- W2788558380 hasAuthorship W2788558380A5059890337 @default.
- W2788558380 hasAuthorship W2788558380A5074911294 @default.
- W2788558380 hasConcept C116263406 @default.
- W2788558380 hasConcept C126322002 @default.
- W2788558380 hasConcept C150903083 @default.
- W2788558380 hasConcept C159985019 @default.
- W2788558380 hasConcept C185592680 @default.
- W2788558380 hasConcept C192562407 @default.
- W2788558380 hasConcept C202751555 @default.
- W2788558380 hasConcept C207001950 @default.
- W2788558380 hasConcept C2776151105 @default.
- W2788558380 hasConcept C2777056448 @default.
- W2788558380 hasConcept C2777135253 @default.
- W2788558380 hasConcept C2777714996 @default.
- W2788558380 hasConcept C2777807558 @default.
- W2788558380 hasConcept C2780512811 @default.