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• W2788893203 abstract "Ammonia-oxidizing archaea (AOA) within the phylum Thaumarchaeota are the only known aerobic ammonia oxidizers in geothermal environments. Although molecular data indicate the presence of phylogenetically diverse AOA from the Nitrosocaldus clade, group 1.1b and group 1.1a Thaumarchaeota in terrestrial high-temperature habitats, only one enrichment culture of an AOA thriving above 50°C has been reported and functionally analyzed. In this study, we physiologically and genomically characterized a newly discovered thaumarchaeon from the deep-branching Nitrosocaldaceae family of which we have obtained a high (∼85%) enrichment from biofilm of an Icelandic hot spring (73°C). This AOA, which we provisionally refer to as Candidatus Nitrosocaldus islandicus, is an obligately thermophilic, aerobic chemolithoautotrophic ammonia oxidizer, which stoichiometrically converts ammonia to nitrite at temperatures between 50 and 70°C. Ca. N. islandicus encodes the expected repertoire of enzymes proposed to be required for archaeal ammonia oxidation, but unexpectedly lacks a nirK gene and also possesses no identifiable other enzyme for nitric oxide (NO) generation. Nevertheless, ammonia oxidation by this AOA appears to be NO-dependent as Ca. N. islandicus is, like all other tested AOA, inhibited by the addition of an NO scavenger. Furthermore, comparative genomics revealed that Ca. N. islandicus has the potential for aromatic amino acid fermentation as its genome encodes an indolepyruvate oxidoreductase (iorAB) as well as a type 3b hydrogenase, which are not present in any other sequenced AOA. A further surprising genomic feature of this thermophilic ammonia oxidizer is the absence of DNA polymerase D genes - one of the predominant replicative DNA polymerases in all other ammonia-oxidizing Thaumarchaeota. Collectively, our findings suggest that metabolic versatility and DNA replication might differ substantially between obligately thermophilic and other AOA." @default.
• W2788893203 created "2018-03-06" @default.
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• W2788893203 date "2018-02-14" @default.
• W2788893203 modified "2023-10-18" @default.
• W2788893203 title "Cultivation and Genomic Analysis of “Candidatus Nitrosocaldus islandicus,” an Obligately Thermophilic, Ammonia-Oxidizing Thaumarchaeon from a Hot Spring Biofilm in Graendalur Valley, Iceland" @default.
• W2788893203 cites W1519054322 @default.
• W2788893203 cites W1539009580 @default.
• W2788893203 cites W1539176720 @default.
• W2788893203 cites W1564565358 @default.
• W2788893203 cites W1566902586 @default.
• W2788893203 cites W1570684276 @default.
• W2788893203 cites W1590141371 @default.
• W2788893203 cites W1597143667 @default.
• W2788893203 cites W1597471552 @default.
• W2788893203 cites W1606825036 @default.
• W2788893203 cites W1661708608 @default.
• W2788893203 cites W1701869895 @default.
• W2788893203 cites W1803102843 @default.
• W2788893203 cites W1850412500 @default.
• W2788893203 cites W1878018588 @default.
• W2788893203 cites W1899501281 @default.
• W2788893203 cites W1918192518 @default.
• W2788893203 cites W1965026439 @default.
• W2788893203 cites W1966058421 @default.
• W2788893203 cites W1969141930 @default.
• W2788893203 cites W1972162975 @default.
• W2788893203 cites W1981436073 @default.
• W2788893203 cites W1981690779 @default.
• W2788893203 cites W1985160714 @default.
• W2788893203 cites W1987448323 @default.
• W2788893203 cites W1987854245 @default.
• W2788893203 cites W1991378003 @default.
• W2788893203 cites W2002187950 @default.
• W2788893203 cites W2010856921 @default.
• W2788893203 cites W2015388145 @default.
• W2788893203 cites W2016138657 @default.
• W2788893203 cites W2023858439 @default.
• W2788893203 cites W2023889836 @default.
• W2788893203 cites W2026240074 @default.
• W2788893203 cites W2029949617 @default.
• W2788893203 cites W2031005202 @default.
• W2788893203 cites W2031611770 @default.
• W2788893203 cites W2032604387 @default.
• W2788893203 cites W2035775871 @default.
• W2788893203 cites W2039098799 @default.
• W2788893203 cites W2048617625 @default.
• W2788893203 cites W2054287183 @default.
• W2788893203 cites W2054458212 @default.
• W2788893203 cites W2058036746 @default.
• W2788893203 cites W2058426473 @default.
• W2788893203 cites W2058645511 @default.
• W2788893203 cites W2059392328 @default.
• W2788893203 cites W2060565559 @default.
• W2788893203 cites W2062760400 @default.
• W2788893203 cites W2064735458 @default.
• W2788893203 cites W2067297267 @default.
• W2788893203 cites W2067447170 @default.
• W2788893203 cites W2070685168 @default.
• W2788893203 cites W2072762503 @default.
• W2788893203 cites W2075451309 @default.
• W2788893203 cites W2080322588 @default.
• W2788893203 cites W2083678046 @default.
• W2788893203 cites W2084694036 @default.
• W2788893203 cites W2088139692 @default.
• W2788893203 cites W2091283955 @default.
• W2788893203 cites W2094465124 @default.
• W2788893203 cites W2098149214 @default.
• W2788893203 cites W2098515054 @default.
• W2788893203 cites W2102334286 @default.
• W2788893203 cites W2104398544 @default.
• W2788893203 cites W2107240865 @default.
• W2788893203 cites W2107511706 @default.
• W2788893203 cites W2110282379 @default.
• W2788893203 cites W2111097957 @default.
• W2788893203 cites W2111165894 @default.
• W2788893203 cites W2111764991 @default.
• W2788893203 cites W2112364185 @default.
• W2788893203 cites W2120460465 @default.
• W2788893203 cites W2120667954 @default.
• W2788893203 cites W2123912011 @default.
• W2788893203 cites W2124088653 @default.
• W2788893203 cites W2124351063 @default.
• W2788893203 cites W2124678879 @default.
• W2788893203 cites W2125591244 @default.
• W2788893203 cites W2128436130 @default.
• W2788893203 cites W2128777911 @default.
• W2788893203 cites W2129734695 @default.
• W2788893203 cites W2130167404 @default.
• W2788893203 cites W2130547198 @default.
• W2788893203 cites W2136252135 @default.

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