Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788893307> ?p ?o ?g. }
- W2788893307 endingPage "446" @default.
- W2788893307 startingPage "446" @default.
- W2788893307 abstract "The temporomandibular joint (TMJ) is an articulation formed between the temporal bone and the mandibular condyle which is commonly affected. These affections are often so painful during fundamental oral activities that patients have lower quality of life. Limitations of therapeutics for severe TMJ diseases have led to increased interest in regenerative strategies combining stem cells, implantable scaffolds and well-targeting bioactive molecules. To succeed in functional and structural regeneration of TMJ is very challenging. Innovative strategies and biomaterials are absolutely crucial because TMJ can be considered as one of the most difficult tissues to regenerate due to its limited healing capacity, its unique histological and structural properties and the necessity for long-term prevention of its ossified or fibrous adhesions. The ideal approach for TMJ regeneration is a unique scaffold functionalized with an osteochondral molecular gradient containing a single stem cell population able to undergo osteogenic and chondrogenic differentiation such as BMSCs, ADSCs or DPSCs. The key for this complex regeneration is the functionalization with active molecules such as IGF-1, TGF-β1 or bFGF. This regeneration can be optimized by nano/micro-assisted functionalization and by spatiotemporal drug delivery systems orchestrating the 3D formation of TMJ tissues." @default.
- W2788893307 created "2018-03-06" @default.
- W2788893307 creator A5009462531 @default.
- W2788893307 creator A5012393958 @default.
- W2788893307 creator A5027930960 @default.
- W2788893307 creator A5046117202 @default.
- W2788893307 creator A5050707879 @default.
- W2788893307 creator A5058340269 @default.
- W2788893307 creator A5060295267 @default.
- W2788893307 creator A5061509082 @default.
- W2788893307 creator A5062720421 @default.
- W2788893307 creator A5071919059 @default.
- W2788893307 creator A5075509277 @default.
- W2788893307 creator A5081224847 @default.
- W2788893307 date "2018-02-02" @default.
- W2788893307 modified "2023-10-15" @default.
- W2788893307 title "Temporomandibular Joint Regenerative Medicine" @default.
- W2788893307 cites W1520590489 @default.
- W2788893307 cites W1570324702 @default.
- W2788893307 cites W1585147043 @default.
- W2788893307 cites W1588451571 @default.
- W2788893307 cites W1628369443 @default.
- W2788893307 cites W1770795329 @default.
- W2788893307 cites W1840950046 @default.
- W2788893307 cites W1843465513 @default.
- W2788893307 cites W1903942872 @default.
- W2788893307 cites W1909934830 @default.
- W2788893307 cites W1923301130 @default.
- W2788893307 cites W1924532062 @default.
- W2788893307 cites W1964049504 @default.
- W2788893307 cites W1964640087 @default.
- W2788893307 cites W1964723440 @default.
- W2788893307 cites W1965917629 @default.
- W2788893307 cites W1966396867 @default.
- W2788893307 cites W1969122374 @default.
- W2788893307 cites W1970182425 @default.
- W2788893307 cites W1972583065 @default.
- W2788893307 cites W1974638778 @default.
- W2788893307 cites W1975261746 @default.
- W2788893307 cites W1977373895 @default.
- W2788893307 cites W1979118540 @default.
- W2788893307 cites W1981072821 @default.
- W2788893307 cites W1982289725 @default.
- W2788893307 cites W1982516116 @default.
- W2788893307 cites W1983953966 @default.
- W2788893307 cites W1984850558 @default.
- W2788893307 cites W1986141694 @default.
- W2788893307 cites W1987732447 @default.
- W2788893307 cites W1989727648 @default.
- W2788893307 cites W1993298115 @default.
- W2788893307 cites W1993921392 @default.
- W2788893307 cites W1994837985 @default.
- W2788893307 cites W1995500131 @default.
- W2788893307 cites W1996611836 @default.
- W2788893307 cites W1997878563 @default.
- W2788893307 cites W1998431553 @default.
- W2788893307 cites W1998944648 @default.
- W2788893307 cites W1999003232 @default.
- W2788893307 cites W1999518950 @default.
- W2788893307 cites W1999599415 @default.
- W2788893307 cites W2004526732 @default.
- W2788893307 cites W2004920571 @default.
- W2788893307 cites W2007310752 @default.
- W2788893307 cites W2007852710 @default.
- W2788893307 cites W2008736248 @default.
- W2788893307 cites W2012930640 @default.
- W2788893307 cites W2013613206 @default.
- W2788893307 cites W2013976086 @default.
- W2788893307 cites W2014068204 @default.
- W2788893307 cites W2014625177 @default.
- W2788893307 cites W2015405201 @default.
- W2788893307 cites W2015639954 @default.
- W2788893307 cites W2016519321 @default.
- W2788893307 cites W2016900858 @default.
- W2788893307 cites W2018362210 @default.
- W2788893307 cites W2018737915 @default.
- W2788893307 cites W2018982288 @default.
- W2788893307 cites W2019893470 @default.
- W2788893307 cites W2021250214 @default.
- W2788893307 cites W2022014544 @default.
- W2788893307 cites W2026663149 @default.
- W2788893307 cites W2027905532 @default.
- W2788893307 cites W2030199625 @default.
- W2788893307 cites W2032256685 @default.
- W2788893307 cites W2034726526 @default.
- W2788893307 cites W2035669447 @default.
- W2788893307 cites W2036545764 @default.
- W2788893307 cites W2038029228 @default.
- W2788893307 cites W2038611660 @default.
- W2788893307 cites W2040035248 @default.
- W2788893307 cites W2041237742 @default.
- W2788893307 cites W2046294433 @default.
- W2788893307 cites W2046526439 @default.
- W2788893307 cites W2046990574 @default.
- W2788893307 cites W2048664475 @default.
- W2788893307 cites W2050008980 @default.
- W2788893307 cites W2053538443 @default.
- W2788893307 cites W2057349098 @default.