Matches in SemOpenAlex for { <https://semopenalex.org/work/W2788894351> ?p ?o ?g. }
- W2788894351 endingPage "15" @default.
- W2788894351 startingPage "15" @default.
- W2788894351 abstract "Glioblastoma is known to be one of the most lethal and untreatable human tumors. Surgery and radiotherapy in combination with classical alkylating agents such as temozolomide offer little hope to escape a poor prognosis. For these reasons, enormous efforts are currently devoted to refine in vivo and in vitro models with the specific goal of finding new molecular aberrant pathways, suitable to be targeted by a variety of therapeutic approaches, including novel pharmaceutical formulations and immunotherapy strategies. In this review, we will first discuss current molecular classification based on genomic and transcriptomic criteria. Also, the state of the art in current clinical practice for glioblastoma therapy in the light of the recent molecular classification, together with ongoing phases II and III clinical trials, will be described. Finally, new pharmaceutical formulations such as nanoparticles and viral vectors, together with new strategies entailing the use of monoclonal antibodies, vaccines and immunotherapy agents, such as checkpoint inhibitors, will also be discussed." @default.
- W2788894351 created "2018-03-06" @default.
- W2788894351 creator A5004557323 @default.
- W2788894351 creator A5054444096 @default.
- W2788894351 creator A5064264483 @default.
- W2788894351 date "2018-01-16" @default.
- W2788894351 modified "2023-09-27" @default.
- W2788894351 title "Glioblastoma under Siege: An Overview of Current Therapeutic Strategies" @default.
- W2788894351 cites W1568849673 @default.
- W2788894351 cites W1588685142 @default.
- W2788894351 cites W1930411354 @default.
- W2788894351 cites W1978756138 @default.
- W2788894351 cites W1984906180 @default.
- W2788894351 cites W1993451273 @default.
- W2788894351 cites W1994778014 @default.
- W2788894351 cites W2024672608 @default.
- W2788894351 cites W2037173620 @default.
- W2788894351 cites W2040827479 @default.
- W2788894351 cites W2041621047 @default.
- W2788894351 cites W2074111828 @default.
- W2788894351 cites W2080789936 @default.
- W2788894351 cites W2083682712 @default.
- W2788894351 cites W2086626740 @default.
- W2788894351 cites W2089482729 @default.
- W2788894351 cites W2090732350 @default.
- W2788894351 cites W2105100844 @default.
- W2788894351 cites W2109816625 @default.
- W2788894351 cites W2117255241 @default.
- W2788894351 cites W2118982164 @default.
- W2788894351 cites W2137382956 @default.
- W2788894351 cites W2137466593 @default.
- W2788894351 cites W2139923932 @default.
- W2788894351 cites W2145489645 @default.
- W2788894351 cites W2149999651 @default.
- W2788894351 cites W2154220948 @default.
- W2788894351 cites W2159817656 @default.
- W2788894351 cites W2161289668 @default.
- W2788894351 cites W2168056656 @default.
- W2788894351 cites W2170558349 @default.
- W2788894351 cites W2203230817 @default.
- W2788894351 cites W2209618509 @default.
- W2788894351 cites W2254399833 @default.
- W2788894351 cites W2263206910 @default.
- W2788894351 cites W2263248967 @default.
- W2788894351 cites W2321438175 @default.
- W2788894351 cites W2392045628 @default.
- W2788894351 cites W2489012250 @default.
- W2788894351 cites W2526011086 @default.
- W2788894351 cites W2560367415 @default.
- W2788894351 cites W2561745256 @default.
- W2788894351 cites W2566753678 @default.
- W2788894351 cites W2567424265 @default.
- W2788894351 cites W2593586113 @default.
- W2788894351 cites W2603523955 @default.
- W2788894351 cites W2604812571 @default.
- W2788894351 cites W2604975779 @default.
- W2788894351 cites W2604996547 @default.
- W2788894351 cites W2615165013 @default.
- W2788894351 cites W2615804302 @default.
- W2788894351 cites W2659205250 @default.
- W2788894351 cites W2726008343 @default.
- W2788894351 cites W2738946651 @default.
- W2788894351 cites W2740134922 @default.
- W2788894351 cites W2740650604 @default.
- W2788894351 cites W2742450412 @default.
- W2788894351 cites W2744510926 @default.
- W2788894351 cites W2749747068 @default.
- W2788894351 cites W2756050810 @default.
- W2788894351 cites W2765082845 @default.
- W2788894351 cites W2765291080 @default.
- W2788894351 cites W2766649683 @default.
- W2788894351 cites W2769229429 @default.
- W2788894351 doi "https://doi.org/10.3390/brainsci8010015" @default.
- W2788894351 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5789346" @default.
- W2788894351 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29337870" @default.
- W2788894351 hasPublicationYear "2018" @default.
- W2788894351 type Work @default.
- W2788894351 sameAs 2788894351 @default.
- W2788894351 citedByCount "97" @default.
- W2788894351 countsByYear W27888943512018 @default.
- W2788894351 countsByYear W27888943512019 @default.
- W2788894351 countsByYear W27888943512020 @default.
- W2788894351 countsByYear W27888943512021 @default.
- W2788894351 countsByYear W27888943512022 @default.
- W2788894351 countsByYear W27888943512023 @default.
- W2788894351 crossrefType "journal-article" @default.
- W2788894351 hasAuthorship W2788894351A5004557323 @default.
- W2788894351 hasAuthorship W2788894351A5054444096 @default.
- W2788894351 hasAuthorship W2788894351A5064264483 @default.
- W2788894351 hasBestOaLocation W27888943511 @default.
- W2788894351 hasConcept C126322002 @default.
- W2788894351 hasConcept C159654299 @default.
- W2788894351 hasConcept C203014093 @default.
- W2788894351 hasConcept C2776194525 @default.
- W2788894351 hasConcept C2777389519 @default.
- W2788894351 hasConcept C2777701055 @default.
- W2788894351 hasConcept C3020616263 @default.
- W2788894351 hasConcept C502942594 @default.