Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789413652> ?p ?o ?g. }
- W2789413652 abstract "Abstract The collagen-based tissues of animals are hierarchical structures: even tendon, the simplest collagenous tissue, has seven to eight levels of hierarchy. Tailoring tissue structure to match physiological function can occur at many different levels. We wanted to know if the control of tissue architecture to achieve function extends down to the nanoscale level of the individual, cable-like collagen fibrils. Using tendons from young adult bovine forelimbs, we performed stress-strain experiments on single collagen fibrils extracted from tendons with positional function, and tendons with energy storing function. Collagen fibrils from the two tendon types, which have known differences in intermolecular crosslinking, showed numerous differences in their responses to elongation. Unlike those from positional tendons, fibrils from energy storing tendons showed high strain stiffening and resistance to disruption in both molecular packing and conformation, helping to explain how these high stress tissues withstand millions of loading cycles with little reparative remodeling. Functional differences in load-bearing tissues are accompanied by important differences in nanoscale collagen fibril structure." @default.
- W2789413652 created "2018-03-29" @default.
- W2789413652 creator A5025750591 @default.
- W2789413652 creator A5037537996 @default.
- W2789413652 creator A5042223307 @default.
- W2789413652 creator A5059211017 @default.
- W2789413652 creator A5068429291 @default.
- W2789413652 creator A5069686330 @default.
- W2789413652 date "2018-03-13" @default.
- W2789413652 modified "2023-10-16" @default.
- W2789413652 title "In tendons, differing physiological requirements lead to functionally distinct nanostructures" @default.
- W2789413652 cites W1512474466 @default.
- W2789413652 cites W1571686214 @default.
- W2789413652 cites W1579799438 @default.
- W2789413652 cites W1824922455 @default.
- W2789413652 cites W1966636560 @default.
- W2789413652 cites W1971465518 @default.
- W2789413652 cites W1973044208 @default.
- W2789413652 cites W1980964205 @default.
- W2789413652 cites W1988254733 @default.
- W2789413652 cites W1997630758 @default.
- W2789413652 cites W1999706433 @default.
- W2789413652 cites W2013244204 @default.
- W2789413652 cites W2018244125 @default.
- W2789413652 cites W2021230511 @default.
- W2789413652 cites W2022300194 @default.
- W2789413652 cites W2024305546 @default.
- W2789413652 cites W2043861531 @default.
- W2789413652 cites W2053506111 @default.
- W2789413652 cites W2054221638 @default.
- W2789413652 cites W2056438456 @default.
- W2789413652 cites W2059525406 @default.
- W2789413652 cites W2070899131 @default.
- W2789413652 cites W2071668615 @default.
- W2789413652 cites W2078672212 @default.
- W2789413652 cites W2080439666 @default.
- W2789413652 cites W2082234179 @default.
- W2789413652 cites W2085802241 @default.
- W2789413652 cites W2089051448 @default.
- W2789413652 cites W2092333030 @default.
- W2789413652 cites W2103378167 @default.
- W2789413652 cites W2109440951 @default.
- W2789413652 cites W2112985937 @default.
- W2789413652 cites W2113459043 @default.
- W2789413652 cites W2114379291 @default.
- W2789413652 cites W2117255087 @default.
- W2789413652 cites W2125413204 @default.
- W2789413652 cites W2125994830 @default.
- W2789413652 cites W2127661946 @default.
- W2789413652 cites W2130227698 @default.
- W2789413652 cites W2143659399 @default.
- W2789413652 cites W2146747926 @default.
- W2789413652 cites W2157714820 @default.
- W2789413652 cites W2161391346 @default.
- W2789413652 cites W2171531663 @default.
- W2789413652 cites W2215613488 @default.
- W2789413652 cites W2255737590 @default.
- W2789413652 cites W2334369213 @default.
- W2789413652 cites W2339194825 @default.
- W2789413652 cites W2420093588 @default.
- W2789413652 cites W2515078836 @default.
- W2789413652 cites W2519748907 @default.
- W2789413652 cites W2570318733 @default.
- W2789413652 cites W2601951312 @default.
- W2789413652 cites W2606250728 @default.
- W2789413652 cites W3105543996 @default.
- W2789413652 doi "https://doi.org/10.1038/s41598-018-22741-8" @default.
- W2789413652 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5849720" @default.
- W2789413652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29535366" @default.
- W2789413652 hasPublicationYear "2018" @default.
- W2789413652 type Work @default.
- W2789413652 sameAs 2789413652 @default.
- W2789413652 citedByCount "50" @default.
- W2789413652 countsByYear W27894136522018 @default.
- W2789413652 countsByYear W27894136522019 @default.
- W2789413652 countsByYear W27894136522020 @default.
- W2789413652 countsByYear W27894136522021 @default.
- W2789413652 countsByYear W27894136522022 @default.
- W2789413652 countsByYear W27894136522023 @default.
- W2789413652 crossrefType "journal-article" @default.
- W2789413652 hasAuthorship W2789413652A5025750591 @default.
- W2789413652 hasAuthorship W2789413652A5037537996 @default.
- W2789413652 hasAuthorship W2789413652A5042223307 @default.
- W2789413652 hasAuthorship W2789413652A5059211017 @default.
- W2789413652 hasAuthorship W2789413652A5068429291 @default.
- W2789413652 hasAuthorship W2789413652A5069686330 @default.
- W2789413652 hasBestOaLocation W27894136521 @default.
- W2789413652 hasConcept C105702510 @default.
- W2789413652 hasConcept C112950240 @default.
- W2789413652 hasConcept C12554922 @default.
- W2789413652 hasConcept C14036430 @default.
- W2789413652 hasConcept C159985019 @default.
- W2789413652 hasConcept C185592680 @default.
- W2789413652 hasConcept C192562407 @default.
- W2789413652 hasConcept C27523624 @default.
- W2789413652 hasConcept C2778022156 @default.
- W2789413652 hasConcept C2780105995 @default.
- W2789413652 hasConcept C3019161014 @default.
- W2789413652 hasConcept C33947775 @default.
- W2789413652 hasConcept C86803240 @default.