FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789471232> ?p ?o ?g. }

• W2789471232 endingPage "359" @default.
• W2789471232 startingPage "350" @default.
• W2789471232 abstract "<b><i>Background/Aims:</i></b> IgA nephropathy is associated with aberrant <i>O</i>-glycosylation of IgA1, which is recognized by autoantibodies leading to the formation of circulating immune complexes. Some of them, after deposition into kidney mesangium, trigger glomerular injury. In patients with active disease nonresponding to angiotensin-converting enzyme inhibitors or angiotensin II blockers, corticosteroids are recommended. <b><i>Methods:</i></b> The relationship between the corticosteroid therapy and serum levels of IgA, aberrantly <i>O</i>-glycosylated IgA1, IgA-containing immune complexes and their mesangioproliferative activity was analyzed in IgA nephropathy patients and disease and healthy controls. <b><i>Results:</i></b> Prednisone therapy significantly reduced proteinuria and levels of serum IgA, galactose-deficient IgA1, and IgA-IgG immune complexes in IgA nephropathy patients and thus reduced differences in all of the above parameters between IgAN patients and control groups. A moderate but not significant reduction of mesangioproliferative potential of IgA-IgG immune complexes and IgA sialylation was detected. <b><i>Conclusion:</i></b> The prednisone therapy reduces overall aberrancy in IgA1 <i>O</i>-glycosylation in IgA nephropathy patients, but the measurement of IgA1 parameters does not allow us to predict the prednisone therapy outcome in individual patients." @default.
• W2789471232 created "2018-03-29" @default.
• W2789471232 creator A5000956973 @default.
• W2789471232 creator A5005323235 @default.
• W2789471232 creator A5018497189 @default.
• W2789471232 creator A5039430105 @default.
• W2789471232 creator A5051273412 @default.
• W2789471232 creator A5058155127 @default.
• W2789471232 creator A5063884465 @default.
• W2789471232 creator A5069751537 @default.
• W2789471232 creator A5070363000 @default.
• W2789471232 creator A5072534912 @default.
• W2789471232 creator A5088505850 @default.
• W2789471232 creator A5091730504 @default.
• W2789471232 date "2018-01-01" @default.
• W2789471232 modified "2023-09-30" @default.
• W2789471232 title "Glucocorticoids Reduce Aberrant O-Glycosylation of IgA1 in IgA Nephropathy Patients" @default.
• W2789471232 cites W1965279497 @default.
• W2789471232 cites W1967907448 @default.
• W2789471232 cites W1977999863 @default.
• W2789471232 cites W2007058211 @default.
• W2789471232 cites W2007731313 @default.
• W2789471232 cites W2026103095 @default.
• W2789471232 cites W2040706558 @default.
• W2789471232 cites W2058154849 @default.
• W2789471232 cites W2077851831 @default.
• W2789471232 cites W2086627106 @default.
• W2789471232 cites W2087471889 @default.
• W2789471232 cites W2090438027 @default.
• W2789471232 cites W2096190752 @default.
• W2789471232 cites W2100730384 @default.
• W2789471232 cites W2101160849 @default.
• W2789471232 cites W2110648558 @default.
• W2789471232 cites W2112443387 @default.
• W2789471232 cites W2116716125 @default.
• W2789471232 cites W2119118341 @default.
• W2789471232 cites W2119832679 @default.
• W2789471232 cites W2125096231 @default.
• W2789471232 cites W2125247444 @default.
• W2789471232 cites W2126623226 @default.
• W2789471232 cites W2131150081 @default.
• W2789471232 cites W2144669742 @default.
• W2789471232 cites W2171420058 @default.
• W2789471232 cites W2181240763 @default.
• W2789471232 cites W2325203441 @default.
• W2789471232 cites W2336413272 @default.
• W2789471232 cites W2342251436 @default.
• W2789471232 cites W2560110841 @default.
• W2789471232 cites W2588179969 @default.
• W2789471232 cites W2601091467 @default.
• W2789471232 cites W2604206413 @default.
• W2789471232 cites W2738814538 @default.
• W2789471232 cites W2951260600 @default.
• W2789471232 cites W4249213970 @default.
• W2789471232 doi "https://doi.org/10.1159/000487903" @default.
• W2789471232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29529610" @default.
• W2789471232 hasPublicationYear "2018" @default.
• W2789471232 type Work @default.
• W2789471232 sameAs 2789471232 @default.
• W2789471232 citedByCount "12" @default.
• W2789471232 countsByYear W27894712322018 @default.
• W2789471232 countsByYear W27894712322020 @default.
• W2789471232 countsByYear W27894712322021 @default.
• W2789471232 countsByYear W27894712322022 @default.
• W2789471232 countsByYear W27894712322023 @default.
• W2789471232 crossrefType "journal-article" @default.
• W2789471232 hasAuthorship W2789471232A5000956973 @default.
• W2789471232 hasAuthorship W2789471232A5005323235 @default.
• W2789471232 hasAuthorship W2789471232A5018497189 @default.
• W2789471232 hasAuthorship W2789471232A5039430105 @default.
• W2789471232 hasAuthorship W2789471232A5051273412 @default.
• W2789471232 hasAuthorship W2789471232A5058155127 @default.
• W2789471232 hasAuthorship W2789471232A5063884465 @default.
• W2789471232 hasAuthorship W2789471232A5069751537 @default.
• W2789471232 hasAuthorship W2789471232A5070363000 @default.
• W2789471232 hasAuthorship W2789471232A5072534912 @default.
• W2789471232 hasAuthorship W2789471232A5088505850 @default.
• W2789471232 hasAuthorship W2789471232A5091730504 @default.
• W2789471232 hasBestOaLocation W27894712321 @default.
• W2789471232 hasConcept C126322002 @default.
• W2789471232 hasConcept C134018914 @default.
• W2789471232 hasConcept C159654299 @default.
• W2789471232 hasConcept C163764329 @default.
• W2789471232 hasConcept C203014093 @default.
• W2789471232 hasConcept C2778720950 @default.
• W2789471232 hasConcept C2779102806 @default.
• W2789471232 hasConcept C2780091579 @default.
• W2789471232 hasConcept C2780368995 @default.
• W2789471232 hasConcept C2780898057 @default.
• W2789471232 hasConcept C2781184683 @default.
• W2789471232 hasConcept C555293320 @default.
• W2789471232 hasConcept C71924100 @default.
• W2789471232 hasConcept C8891405 @default.
• W2789471232 hasConceptScore W2789471232C126322002 @default.
• W2789471232 hasConceptScore W2789471232C134018914 @default.
• W2789471232 hasConceptScore W2789471232C159654299 @default.
• W2789471232 hasConceptScore W2789471232C163764329 @default.
• W2789471232 hasConceptScore W2789471232C203014093 @default.

• next