Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789522479> ?p ?o ?g. }
- W2789522479 abstract "A series of novel ruthenium(II)–cymene complexes ( 1 – 8 ) containing substituted pyridyl–thiazole ligands, [Ru(η 6 ‐ p ‐cymene)(L)Cl]Cl (L = N,N‐chelating derivatives), have been synthesized and characterized using elemental analysis, infrared, 1 H NMR and 13 C NMR spectroscopies and mass spectrometry. All these complexes not only display marked cytotoxicity in vitro against three different human cancer cell lines (HeLa, A549 and MDA‐MB‐231), but also exhibit promising anti‐metastatic activity at sub‐cytotoxic concentrations. Cell cycle analysis shows that the ruthenium(II) complex‐induced growth inhibition was mainly caused by S‐phase cell cycle arrest. Further protein level analysis suggests that compound 5 may exert antitumor activity via a p53‐independent mechanism." @default.
- W2789522479 created "2018-03-29" @default.
- W2789522479 creator A5004604699 @default.
- W2789522479 creator A5012278873 @default.
- W2789522479 creator A5059561651 @default.
- W2789522479 creator A5070225387 @default.
- W2789522479 date "2018-03-08" @default.
- W2789522479 modified "2023-09-23" @default.
- W2789522479 title "Synthesis, cytotoxicity and anti-metastatic properties of new pyridyl-thiazole arene ruthenium(II) complexes" @default.
- W2789522479 cites W1650797637 @default.
- W2789522479 cites W1964511337 @default.
- W2789522479 cites W1965239527 @default.
- W2789522479 cites W1969345055 @default.
- W2789522479 cites W1985920758 @default.
- W2789522479 cites W1987604182 @default.
- W2789522479 cites W1994156064 @default.
- W2789522479 cites W1999481325 @default.
- W2789522479 cites W2001976945 @default.
- W2789522479 cites W2002610019 @default.
- W2789522479 cites W2005723165 @default.
- W2789522479 cites W2014588550 @default.
- W2789522479 cites W2016450375 @default.
- W2789522479 cites W2017346763 @default.
- W2789522479 cites W2027845786 @default.
- W2789522479 cites W2037380118 @default.
- W2789522479 cites W2041807155 @default.
- W2789522479 cites W2042390732 @default.
- W2789522479 cites W2043465974 @default.
- W2789522479 cites W2045894986 @default.
- W2789522479 cites W2053861556 @default.
- W2789522479 cites W2059860479 @default.
- W2789522479 cites W2066825427 @default.
- W2789522479 cites W2075243573 @default.
- W2789522479 cites W2086641174 @default.
- W2789522479 cites W2090488372 @default.
- W2789522479 cites W2117097853 @default.
- W2789522479 cites W2119968469 @default.
- W2789522479 cites W2120831117 @default.
- W2789522479 cites W2130177169 @default.
- W2789522479 cites W2130728974 @default.
- W2789522479 cites W2139848821 @default.
- W2789522479 cites W2161980885 @default.
- W2789522479 cites W2164277862 @default.
- W2789522479 cites W2274595380 @default.
- W2789522479 cites W2295820531 @default.
- W2789522479 cites W2315058715 @default.
- W2789522479 cites W2321978197 @default.
- W2789522479 cites W2334494402 @default.
- W2789522479 cites W2354190331 @default.
- W2789522479 cites W2613717599 @default.
- W2789522479 cites W263343890 @default.
- W2789522479 cites W4244473919 @default.
- W2789522479 doi "https://doi.org/10.1002/aoc.4311" @default.
- W2789522479 hasPublicationYear "2018" @default.
- W2789522479 type Work @default.
- W2789522479 sameAs 2789522479 @default.
- W2789522479 citedByCount "5" @default.
- W2789522479 countsByYear W27895224792019 @default.
- W2789522479 countsByYear W27895224792022 @default.
- W2789522479 crossrefType "journal-article" @default.
- W2789522479 hasAuthorship W2789522479A5004604699 @default.
- W2789522479 hasAuthorship W2789522479A5012278873 @default.
- W2789522479 hasAuthorship W2789522479A5059561651 @default.
- W2789522479 hasAuthorship W2789522479A5070225387 @default.
- W2789522479 hasConcept C109316439 @default.
- W2789522479 hasConcept C155647269 @default.
- W2789522479 hasConcept C161790260 @default.
- W2789522479 hasConcept C178790620 @default.
- W2789522479 hasConcept C185592680 @default.
- W2789522479 hasConcept C197404232 @default.
- W2789522479 hasConcept C202751555 @default.
- W2789522479 hasConcept C2777366897 @default.
- W2789522479 hasConcept C2778464347 @default.
- W2789522479 hasConcept C55493867 @default.
- W2789522479 hasConcept C555196967 @default.
- W2789522479 hasConcept C71240020 @default.
- W2789522479 hasConceptScore W2789522479C109316439 @default.
- W2789522479 hasConceptScore W2789522479C155647269 @default.
- W2789522479 hasConceptScore W2789522479C161790260 @default.
- W2789522479 hasConceptScore W2789522479C178790620 @default.
- W2789522479 hasConceptScore W2789522479C185592680 @default.
- W2789522479 hasConceptScore W2789522479C197404232 @default.
- W2789522479 hasConceptScore W2789522479C202751555 @default.
- W2789522479 hasConceptScore W2789522479C2777366897 @default.
- W2789522479 hasConceptScore W2789522479C2778464347 @default.
- W2789522479 hasConceptScore W2789522479C55493867 @default.
- W2789522479 hasConceptScore W2789522479C555196967 @default.
- W2789522479 hasConceptScore W2789522479C71240020 @default.
- W2789522479 hasFunder F4320321001 @default.
- W2789522479 hasIssue "5" @default.
- W2789522479 hasLocation W27895224791 @default.
- W2789522479 hasOpenAccess W2789522479 @default.
- W2789522479 hasPrimaryLocation W27895224791 @default.
- W2789522479 hasRelatedWork W1108974620 @default.
- W2789522479 hasRelatedWork W1980010718 @default.
- W2789522479 hasRelatedWork W2013816495 @default.
- W2789522479 hasRelatedWork W2024049118 @default.
- W2789522479 hasRelatedWork W2045318320 @default.
- W2789522479 hasRelatedWork W2071649533 @default.
- W2789522479 hasRelatedWork W2089376439 @default.