FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789583640> ?p ?o ?g. }

• W2789583640 endingPage "353" @default.
• W2789583640 startingPage "344" @default.
• W2789583640 abstract "Aims Iron deficiency is highly prevalent in Southeast Asians with heart failure (HF) and associated with worse outcomes. This trial aimed to assess the effect of intravenous iron in Southeast Asians hospitalized with decompensated HF. Methods and results Fifty patients hospitalized for acute decompensated HF, regardless of ejection fraction, with iron deficiency (defined as serum ferritin <300 ng/mL if transferrin saturation is <20%) were randomized to receive either one dose of intravenous ferric carboxymaltose (FCM) 1000 mg or placebo (0.9% saline) following HF stabilization and before discharge in two Singapore tertiary centres. The primary endpoint was difference in 6-min walk test (6MWT) distance over 12 weeks, while secondary endpoints were quality of life assessed using validated Kansas City Cardiomyopathy Questionnaire (KCCQ) and Visual Analogue Scale (VAS). Improvement in 6MWT distance at Week 12 was observed in both FCM and placebo groups (from 252 ± 123 to 334 ± 128 m and from 243 ± 67 to 301 ± 83 m, respectively). Unadjusted analysis showed 6MWT distance for FCM exceeded that for placebo, but adjustment for baseline covariates and time attenuated this effect {adjusted mean difference between groups: 0.88 m [95% confidence interval (CI) −30.2 to 32.0, P = 0.956]}. KCCQ overall summary and VAS were similar in both groups [adjusted mean difference: KCCQ −1.48 (95% CI −8.27 to 5.31, P = 0.670) and VAS 0.26 (95% CI −0.33 to 0.86, P = 0.386)]. FCM was well tolerated with no serious treatment-related adverse events. Conclusions Intravenous FCM administered pre-discharge in Southeast Asians hospitalized with decompensated HF is clinically feasible. Changes in 6MWT distance should be measured beyond Week 12 to account for background therapy effects." @default.
• W2789583640 created "2018-03-29" @default.
• W2789583640 creator A5002582270 @default.
• W2789583640 creator A5003274991 @default.
• W2789583640 creator A5031262573 @default.
• W2789583640 creator A5034789138 @default.
• W2789583640 creator A5043224002 @default.
• W2789583640 creator A5051418070 @default.
• W2789583640 creator A5051953643 @default.
• W2789583640 creator A5052221166 @default.
• W2789583640 creator A5056466411 @default.
• W2789583640 creator A5067453123 @default.
• W2789583640 creator A5072304888 @default.
• W2789583640 creator A5072937548 @default.
• W2789583640 creator A5074465225 @default.
• W2789583640 creator A5088670160 @default.
• W2789583640 date "2018-01-18" @default.
• W2789583640 modified "2023-10-13" @default.
• W2789583640 title "Single-dose intravenous iron in Southeast Asian heart failure patients: A pilot randomized placebo-controlled study (PRACTICE-ASIA-HF)" @default.
• W2789583640 cites W162181629 @default.
• W2789583640 cites W1706624733 @default.
• W2789583640 cites W1972388303 @default.
• W2789583640 cites W1982453010 @default.
• W2789583640 cites W1989532142 @default.
• W2789583640 cites W2017704094 @default.
• W2789583640 cites W2018604495 @default.
• W2789583640 cites W2020198029 @default.
• W2789583640 cites W2020862550 @default.
• W2789583640 cites W2028265881 @default.
• W2789583640 cites W2028638220 @default.
• W2789583640 cites W2046551865 @default.
• W2789583640 cites W2087734261 @default.
• W2789583640 cites W2090124984 @default.
• W2789583640 cites W2092480503 @default.
• W2789583640 cites W2105391691 @default.
• W2789583640 cites W2113083124 @default.
• W2789583640 cites W2123394946 @default.
• W2789583640 cites W2124606145 @default.
• W2789583640 cites W2139318112 @default.
• W2789583640 cites W2148669301 @default.
• W2789583640 cites W2163539116 @default.
• W2789583640 cites W2276227009 @default.
• W2789583640 cites W2405122807 @default.
• W2789583640 cites W2427094903 @default.
• W2789583640 cites W3168199625 @default.
• W2789583640 cites W39811204 @default.
• W2789583640 cites W4245666729 @default.
• W2789583640 cites W844825188 @default.
• W2789583640 doi "https://doi.org/10.1002/ehf2.12250" @default.
• W2789583640 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5880664" @default.
• W2789583640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29345426" @default.
• W2789583640 hasPublicationYear "2018" @default.
• W2789583640 type Work @default.
• W2789583640 sameAs 2789583640 @default.
• W2789583640 citedByCount "28" @default.
• W2789583640 countsByYear W27895836402018 @default.
• W2789583640 countsByYear W27895836402019 @default.
• W2789583640 countsByYear W27895836402020 @default.
• W2789583640 countsByYear W27895836402021 @default.
• W2789583640 countsByYear W27895836402022 @default.
• W2789583640 countsByYear W27895836402023 @default.
• W2789583640 crossrefType "journal-article" @default.
• W2789583640 hasAuthorship W2789583640A5002582270 @default.
• W2789583640 hasAuthorship W2789583640A5003274991 @default.
• W2789583640 hasAuthorship W2789583640A5031262573 @default.
• W2789583640 hasAuthorship W2789583640A5034789138 @default.
• W2789583640 hasAuthorship W2789583640A5043224002 @default.
• W2789583640 hasAuthorship W2789583640A5051418070 @default.
• W2789583640 hasAuthorship W2789583640A5051953643 @default.
• W2789583640 hasAuthorship W2789583640A5052221166 @default.
• W2789583640 hasAuthorship W2789583640A5056466411 @default.
• W2789583640 hasAuthorship W2789583640A5067453123 @default.
• W2789583640 hasAuthorship W2789583640A5072304888 @default.
• W2789583640 hasAuthorship W2789583640A5072937548 @default.
• W2789583640 hasAuthorship W2789583640A5074465225 @default.
• W2789583640 hasAuthorship W2789583640A5088670160 @default.
• W2789583640 hasBestOaLocation W27895836401 @default.
• W2789583640 hasConcept C126322002 @default.
• W2789583640 hasConcept C141071460 @default.
• W2789583640 hasConcept C14184104 @default.
• W2789583640 hasConcept C142724271 @default.
• W2789583640 hasConcept C153852466 @default.
• W2789583640 hasConcept C168563851 @default.
• W2789583640 hasConcept C197934379 @default.
• W2789583640 hasConcept C203092338 @default.
• W2789583640 hasConcept C204787440 @default.
• W2789583640 hasConcept C27081682 @default.
• W2789583640 hasConcept C2777417653 @default.
• W2789583640 hasConcept C2778198053 @default.
• W2789583640 hasConcept C2778248108 @default.
• W2789583640 hasConcept C2778319317 @default.
• W2789583640 hasConcept C3020614022 @default.
• W2789583640 hasConcept C44249647 @default.
• W2789583640 hasConcept C71924100 @default.
• W2789583640 hasConcept C78085059 @default.
• W2789583640 hasConceptScore W2789583640C126322002 @default.
• W2789583640 hasConceptScore W2789583640C141071460 @default.
• W2789583640 hasConceptScore W2789583640C14184104 @default.

• next