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• W2789618431 abstract "Dioxins are endocrine-disrupting chemicals, and their effects on reproductive functions are well-documented. The aim of the present study was to measure the levels of reproductive hormones in 42 men residing near a dioxin-contaminated area in Vietnam. We measured levels of 17 2,3,7,8-substituted congeners of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) and four non-ortho polychlorinated biphenyls (PCBs) in blood. Levels of follicle-stimulating hormone, luteinizing hormone, progesterone, prolactin, estradiol, and total testosterone were measured in serum. Blood dioxin levels were elevated; the levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin was 7.3 pg/g fat. Seven of the men had testosterone levels below 250 ng/dL, and nine men had prolactin levels above 9.7 ng/mL. Four PCDD congeners, two PCDF congeners, one PCB congener, and the sum TEQ of PCDDs, PCDDs/Fs, and PCDDs/Fs/PCBs were positively and significantly correlated with prolactin levels. Two PCDD congeners, six PCDF congeners, two PCB congeners, and the TEQs of PCDFs and PCBs were negatively and significantly correlated with testosterone levels. There were no significant correlations between dioxin congeners and follicle-stimulating hormone, luteinizing hormone, or progesterone levels." @default.
• W2789618431 created "2018-03-29" @default.
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• W2789618431 date "2018-07-01" @default.
• W2789618431 modified "2023-10-01" @default.
• W2789618431 title "Association of dioxin exposure and reproductive hormone levels in men living near the Bien Hoa airbase, Vietnam" @default.
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• W2789618431 doi "https://doi.org/10.1016/j.scitotenv.2018.02.094" @default.
• W2789618431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29453177" @default.
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