Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789637186> ?p ?o ?g. }
Showing items 1 to 29 of
29
with 100 items per page.
- W2789637186 abstract "Sarcomas (sarcomata - sa) are neoplasms that have a mesenchymal origin or are differentiating in that direction. Their growth is chaotic and progressive: the cells divide constantly in time and tumor space. They can be caused by viruses, chemical compounds, physical factors or even autoimmune reactions. They result from a disruption in a balance between protooncogenes and suppressor genes. This can be an effect of the accumulation of mutation within those genes, often with the participation of viruses that can modify the cell’s genetic information. The changes in genes are transmitted from one generation of cells to subsequent ones and are irreparable and progressive. Sarcomas are vimentin - positive, S - 100 -negative, LCA - negative and HMB - 45 - negative. They can show positive or negative reactions to keratin and EM. The frequency of sarcomas as compared to cancers is like 1:50 and so they constitute approximately 1% of malignant neoplasms in humans. In animals this ratio is reversed: sarcomas (except in the mammary gland and skin) are far more common than carcinomas. Sarcomas tumors are accompanied by various disturbances in circulation, regressive changes (degeneration, necrosis) and inflammation, including immune reactions or a response to bacterial or fungal co-infection. Sarcomas, similarly to cancers, show neoplastic cannibalism; i.e. an ability of one cell to absorb another cell. Moreover, they are less mature than mother and can show histoformative features. They also manifest a wide range of malignancy features. Because of their localization in deeply lying tissues, the diagnosis is often delayed and the clinical prognosis is poor. ." @default.
- W2789637186 created "2018-03-29" @default.
- W2789637186 creator A5029204493 @default.
- W2789637186 date "2018-01-01" @default.
- W2789637186 modified "2023-09-24" @default.
- W2789637186 title "Pathomorphology of the sarcomas" @default.
- W2789637186 doi "https://doi.org/10.21521/mw.6032" @default.
- W2789637186 hasPublicationYear "2018" @default.
- W2789637186 type Work @default.
- W2789637186 sameAs 2789637186 @default.
- W2789637186 citedByCount "0" @default.
- W2789637186 crossrefType "journal-article" @default.
- W2789637186 hasAuthorship W2789637186A5029204493 @default.
- W2789637186 hasBestOaLocation W27896371861 @default.
- W2789637186 hasConcept C142724271 @default.
- W2789637186 hasConcept C2778256501 @default.
- W2789637186 hasConcept C71924100 @default.
- W2789637186 hasConcept C86803240 @default.
- W2789637186 hasConceptScore W2789637186C142724271 @default.
- W2789637186 hasConceptScore W2789637186C2778256501 @default.
- W2789637186 hasConceptScore W2789637186C71924100 @default.
- W2789637186 hasConceptScore W2789637186C86803240 @default.
- W2789637186 hasLocation W27896371861 @default.
- W2789637186 hasOpenAccess W2789637186 @default.
- W2789637186 hasPrimaryLocation W27896371861 @default.
- W2789637186 isParatext "false" @default.
- W2789637186 isRetracted "false" @default.
- W2789637186 magId "2789637186" @default.
- W2789637186 workType "article" @default.