FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789672292> ?p ?o ?g. }

• W2789672292 endingPage "322" @default.
• W2789672292 startingPage "311" @default.
• W2789672292 abstract "In recent era, nanoparticles (NPs) are widely used in food, medicine and body implants. Besides it's wide use being a foreign particle it may have some noxious effect on the body. To understand the mechanistic role of NPs toxicity, Drosophila appeared to be a superior model organism. Toxicity of several nanoparticles were accessed using Drosophila. The NPs, after oral route of exposure enter into the gut, crosses the barrier of peritrophic membrane and induces apoptosis. The toxicity of NPs within gut resulted in developmental delay, with decrease in pupa count, fly hatching along with weight loss. The adult fly hatched after nanoparticle treatment shows increasing phenotypic defect in various sensory organs as well as in different body parts. Besides phenotypic defect some of the nanoparticle results altered behavioural phenotypes like larva crawling or adult climbing. Alteration of both phenotypic as well as behavioural assay clearly hints that signalling pathway like Notch, Wnt, EGFR etc. get affected due to exposure of nanoparticle. Results from various labs prove that nanoparticle can mediate developmental defect by altering signalling pathways. Since many of the signalling pathways are conserved the effect seen in model organisms cannot be overlooked. All the nanoparticles used in food and medicine should be modified to nullify the toxic effect before used in food and medicine." @default.
• W2789672292 created "2018-03-29" @default.
• W2789672292 creator A5060731648 @default.
• W2789672292 creator A5089760346 @default.
• W2789672292 date "2018-01-01" @default.
• W2789672292 modified "2023-10-16" @default.
• W2789672292 title "A Drosophila Model to Decipher the Toxicity of Nanoparticles Taken Through Oral Routes" @default.
• W2789672292 cites W1483162601 @default.
• W2789672292 cites W1842609426 @default.
• W2789672292 cites W1967637067 @default.
• W2789672292 cites W1969217408 @default.
• W2789672292 cites W1974865223 @default.
• W2789672292 cites W1975443927 @default.
• W2789672292 cites W1978216727 @default.
• W2789672292 cites W1985076352 @default.
• W2789672292 cites W1985269003 @default.
• W2789672292 cites W1986246309 @default.
• W2789672292 cites W1992166069 @default.
• W2789672292 cites W1995621075 @default.
• W2789672292 cites W1995878997 @default.
• W2789672292 cites W2000488657 @default.
• W2789672292 cites W2004328544 @default.
• W2789672292 cites W2007730359 @default.
• W2789672292 cites W2017751726 @default.
• W2789672292 cites W2019035020 @default.
• W2789672292 cites W2029159174 @default.
• W2789672292 cites W2038126953 @default.
• W2789672292 cites W2040243871 @default.
• W2789672292 cites W2040410354 @default.
• W2789672292 cites W2042442387 @default.
• W2789672292 cites W2043167070 @default.
• W2789672292 cites W2050554989 @default.
• W2789672292 cites W2051577430 @default.
• W2789672292 cites W2054467412 @default.
• W2789672292 cites W2056540026 @default.
• W2789672292 cites W2057069198 @default.
• W2789672292 cites W2057387129 @default.
• W2789672292 cites W2064062620 @default.
• W2789672292 cites W2064255874 @default.
• W2789672292 cites W2064367138 @default.
• W2789672292 cites W2064640335 @default.
• W2789672292 cites W2065084683 @default.
• W2789672292 cites W2066685510 @default.
• W2789672292 cites W2070032426 @default.
• W2789672292 cites W2073836753 @default.
• W2789672292 cites W2075551106 @default.
• W2789672292 cites W2076045069 @default.
• W2789672292 cites W2076307233 @default.
• W2789672292 cites W2077826769 @default.
• W2789672292 cites W2080505648 @default.
• W2789672292 cites W2081862861 @default.
• W2789672292 cites W2082511916 @default.
• W2789672292 cites W2084953152 @default.
• W2789672292 cites W2089773350 @default.
• W2789672292 cites W2092886235 @default.
• W2789672292 cites W2094755460 @default.
• W2789672292 cites W2095241405 @default.
• W2789672292 cites W2100286612 @default.
• W2789672292 cites W2104174252 @default.
• W2789672292 cites W2104251127 @default.
• W2789672292 cites W2107272290 @default.
• W2789672292 cites W2107929293 @default.
• W2789672292 cites W2110173648 @default.
• W2789672292 cites W2112676306 @default.
• W2789672292 cites W2114114225 @default.
• W2789672292 cites W2115629461 @default.
• W2789672292 cites W2118481813 @default.
• W2789672292 cites W2121453883 @default.
• W2789672292 cites W2125737305 @default.
• W2789672292 cites W2126041423 @default.
• W2789672292 cites W2128242634 @default.
• W2789672292 cites W2130230700 @default.
• W2789672292 cites W2131802378 @default.
• W2789672292 cites W2141152421 @default.
• W2789672292 cites W2141214816 @default.
• W2789672292 cites W2145697740 @default.
• W2789672292 cites W2145870802 @default.
• W2789672292 cites W2148260760 @default.
• W2789672292 cites W2150220021 @default.
• W2789672292 cites W2151220321 @default.
• W2789672292 cites W2155111869 @default.
• W2789672292 cites W2158332939 @default.
• W2789672292 cites W2158898605 @default.
• W2789672292 cites W2160076513 @default.
• W2789672292 cites W2162142896 @default.
• W2789672292 cites W2167299806 @default.
• W2789672292 cites W2168059777 @default.
• W2789672292 cites W2171278491 @default.
• W2789672292 cites W2279285463 @default.
• W2789672292 cites W2291059105 @default.
• W2789672292 cites W2329583008 @default.
• W2789672292 cites W2396116491 @default.
• W2789672292 cites W2403606518 @default.
• W2789672292 cites W2466411674 @default.
• W2789672292 cites W2511152242 @default.
• W2789672292 cites W2518554426 @default.
• W2789672292 cites W2562691938 @default.
• W2789672292 cites W2604749966 @default.

• next