FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789722416> ?p ?o ?g. }

• W2789722416 endingPage "523" @default.
• W2789722416 startingPage "516" @default.
• W2789722416 abstract "We have investigated the mechanism of plasma-induced water pore formation in model 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) bilayer membrane systems using atomistic molecular dynamics (MD) simulations. Oxidized by reactive oxygen species generated upon the plasma treatment, unsaturated hydrocarbon tails of DOPC lipids are converted into shortened hydrocarbon tails with terminal groups such as peroxide or aldehyde. Among them, the lipids with both hydrocarbon tails oxidized into aldehyde groups are particularly susceptible to the stable water pore formation. By analyzing the water pore formation dynamics, lipid escape, and lipid clustering for the plasma-damaged DOPC membrane systems, we have found that a stable water pore is formed in the membrane region where the plasma-damaged lipids are highly concentrated or locally clustered. In the plasma-damaged lipid-rich region, a continuous water channel through the membrane is easily established with the help of the terminal aldehyde groups in the tails of damaged lipids, and it continuously grows with time to form a stable water pore. The rapid local clustering or domain formation of the plasma-damaged lipids is due to both the hydrophobic mismatch between normal and oxidized DOPC lipids and enhanced lateral diffusion of the oxidized lipids in the membrane. We have also observed that the onset concentration of oxidized lipids for the stable water pore formation is approximately 30% in the model DOPC membrane systems." @default.
• W2789722416 created "2018-03-29" @default.
• W2789722416 creator A5017759697 @default.
• W2789722416 creator A5035871875 @default.
• W2789722416 creator A5091459701 @default.
• W2789722416 date "2018-03-22" @default.
• W2789722416 modified "2023-10-16" @default.
• W2789722416 title "Plasma-induced Water Pore Formation in Model Cell Membranes: Molecular Dynamics Simulation" @default.
• W2789722416 cites W1597706623 @default.
• W2789722416 cites W1686322720 @default.
• W2789722416 cites W1957056581 @default.
• W2789722416 cites W1964991966 @default.
• W2789722416 cites W1965516009 @default.
• W2789722416 cites W1968054181 @default.
• W2789722416 cites W1970104806 @default.
• W2789722416 cites W1970543977 @default.
• W2789722416 cites W1972758026 @default.
• W2789722416 cites W1974257740 @default.
• W2789722416 cites W1974490349 @default.
• W2789722416 cites W1978133924 @default.
• W2789722416 cites W1990962673 @default.
• W2789722416 cites W2011088564 @default.
• W2789722416 cites W2017103564 @default.
• W2789722416 cites W2021884192 @default.
• W2789722416 cites W2029422426 @default.
• W2789722416 cites W2029667189 @default.
• W2789722416 cites W2035687084 @default.
• W2789722416 cites W2038758364 @default.
• W2789722416 cites W2040806491 @default.
• W2789722416 cites W2044067265 @default.
• W2789722416 cites W2047871652 @default.
• W2789722416 cites W2054271024 @default.
• W2789722416 cites W2056172163 @default.
• W2789722416 cites W2057973387 @default.
• W2789722416 cites W2059705643 @default.
• W2789722416 cites W2060688826 @default.
• W2789722416 cites W2061417691 @default.
• W2789722416 cites W2064287832 @default.
• W2789722416 cites W2066414494 @default.
• W2789722416 cites W2067174909 @default.
• W2789722416 cites W2076519801 @default.
• W2789722416 cites W2079213155 @default.
• W2789722416 cites W2092507495 @default.
• W2789722416 cites W2093252444 @default.
• W2789722416 cites W2096466762 @default.
• W2789722416 cites W2116848533 @default.
• W2789722416 cites W2121138440 @default.
• W2789722416 cites W2125744674 @default.
• W2789722416 cites W2127104464 @default.
• W2789722416 cites W2138015656 @default.
• W2789722416 cites W2148320012 @default.
• W2789722416 cites W2150981663 @default.
• W2789722416 cites W2153400793 @default.
• W2789722416 cites W2154109003 @default.
• W2789722416 cites W2159121672 @default.
• W2789722416 cites W2172043643 @default.
• W2789722416 cites W2206954826 @default.
• W2789722416 cites W2260143160 @default.
• W2789722416 cites W2302171264 @default.
• W2789722416 cites W2317837193 @default.
• W2789722416 cites W2328970990 @default.
• W2789722416 cites W2413079434 @default.
• W2789722416 doi "https://doi.org/10.1002/bkcs.11421" @default.
• W2789722416 hasPublicationYear "2018" @default.
• W2789722416 type Work @default.
• W2789722416 sameAs 2789722416 @default.
• W2789722416 citedByCount "1" @default.
• W2789722416 countsByYear W27897224162019 @default.
• W2789722416 crossrefType "journal-article" @default.
• W2789722416 hasAuthorship W2789722416A5017759697 @default.
• W2789722416 hasAuthorship W2789722416A5035871875 @default.
• W2789722416 hasAuthorship W2789722416A5091459701 @default.
• W2789722416 hasConcept C107565407 @default.
• W2789722416 hasConcept C12554922 @default.
• W2789722416 hasConcept C127413603 @default.
• W2789722416 hasConcept C147597530 @default.
• W2789722416 hasConcept C178790620 @default.
• W2789722416 hasConcept C185592680 @default.
• W2789722416 hasConcept C192157962 @default.
• W2789722416 hasConcept C2777207669 @default.
• W2789722416 hasConcept C2780943371 @default.
• W2789722416 hasConcept C39944091 @default.
• W2789722416 hasConcept C41625074 @default.
• W2789722416 hasConcept C42360764 @default.
• W2789722416 hasConcept C55493867 @default.
• W2789722416 hasConcept C59593255 @default.
• W2789722416 hasConcept C86803240 @default.
• W2789722416 hasConceptScore W2789722416C107565407 @default.
• W2789722416 hasConceptScore W2789722416C12554922 @default.
• W2789722416 hasConceptScore W2789722416C127413603 @default.
• W2789722416 hasConceptScore W2789722416C147597530 @default.
• W2789722416 hasConceptScore W2789722416C178790620 @default.
• W2789722416 hasConceptScore W2789722416C185592680 @default.
• W2789722416 hasConceptScore W2789722416C192157962 @default.
• W2789722416 hasConceptScore W2789722416C2777207669 @default.
• W2789722416 hasConceptScore W2789722416C2780943371 @default.
• W2789722416 hasConceptScore W2789722416C39944091 @default.
• W2789722416 hasConceptScore W2789722416C41625074 @default.

• next