FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789758412> ?p ?o ?g. }

• W2789758412 endingPage "18" @default.
• W2789758412 startingPage "13" @default.
• W2789758412 abstract "Type I interferons (IFN), which are immediately induced after most virus infections, are central for direct antiviral immunity and link innate and adaptive immune responses. However, several viruses have evolved strategies to evade the IFN response by preventing IFN induction or blocking IFN signaling pathways. Thus, therapeutic application of exogenous type I IFN or agonists inducing type I IFN responses are a considerable option for future immunotherapies against chronic viral infections. An important part of the type I IFN family are 12 IFNα subtypes, which all bind the same receptor, but significantly differ in their biological activities. Up to date only one IFNα subtype (IFNα2) is being used in clinical treatment against chronic virus infections, however its therapeutic success rate is rather limited, especially during Human Immunodeficiency Virus (HIV) infection. Recent studies addressed the important question if other IFNα subtypes would be more potent against retroviral infections in in vitro and in vivo experiments. Indeed, very potent IFNα subtypes were defined and their antiviral and immunomodulatory properties were characterized. In this review we summarize the recent findings on the role of individual IFNα subtypes during HIV and Simian Immunodeficiency Virus infection. This includes their induction during HIV/SIV infection, their antiretroviral activity and the regulation of immune response against HIV by different IFNα subtypes. The findings might facilitate novel strategies for HIV cure or functional cure studies." @default.
• W2789758412 created "2018-03-29" @default.
• W2789758412 creator A5016243200 @default.
• W2789758412 creator A5069117760 @default.
• W2789758412 creator A5089752592 @default.
• W2789758412 date "2018-04-01" @default.
• W2789758412 modified "2023-10-13" @default.
• W2789758412 title "Interferon α subtypes in HIV infection" @default.
• W2789758412 cites W1834094546 @default.
• W2789758412 cites W1953974801 @default.
• W2789758412 cites W1967475015 @default.
• W2789758412 cites W1970089787 @default.
• W2789758412 cites W1970991419 @default.
• W2789758412 cites W1979386505 @default.
• W2789758412 cites W1985467327 @default.
• W2789758412 cites W1988398150 @default.
• W2789758412 cites W1997031405 @default.
• W2789758412 cites W1997388148 @default.
• W2789758412 cites W2000177767 @default.
• W2789758412 cites W2001409033 @default.
• W2789758412 cites W2001815276 @default.
• W2789758412 cites W2005155731 @default.
• W2789758412 cites W2011308270 @default.
• W2789758412 cites W2013039788 @default.
• W2789758412 cites W2013486480 @default.
• W2789758412 cites W2016749309 @default.
• W2789758412 cites W2026036608 @default.
• W2789758412 cites W2026054459 @default.
• W2789758412 cites W2029323175 @default.
• W2789758412 cites W2038075586 @default.
• W2789758412 cites W2043726848 @default.
• W2789758412 cites W2048513925 @default.
• W2789758412 cites W2049018578 @default.
• W2789758412 cites W2051940924 @default.
• W2789758412 cites W2063082801 @default.
• W2789758412 cites W2066900946 @default.
• W2789758412 cites W2067012451 @default.
• W2789758412 cites W2071613044 @default.
• W2789758412 cites W2075090863 @default.
• W2789758412 cites W2075413744 @default.
• W2789758412 cites W2075527727 @default.
• W2789758412 cites W2077620427 @default.
• W2789758412 cites W2078646756 @default.
• W2789758412 cites W2078660110 @default.
• W2789758412 cites W2079671323 @default.
• W2789758412 cites W2090001019 @default.
• W2789758412 cites W2092603906 @default.
• W2789758412 cites W2101910308 @default.
• W2789758412 cites W2105694629 @default.
• W2789758412 cites W2108040405 @default.
• W2789758412 cites W2112121524 @default.
• W2789758412 cites W2115528382 @default.
• W2789758412 cites W2121632263 @default.
• W2789758412 cites W2137051059 @default.
• W2789758412 cites W2155651193 @default.
• W2789758412 cites W2165070219 @default.
• W2789758412 cites W2167321515 @default.
• W2789758412 cites W2167488639 @default.
• W2789758412 cites W2167661882 @default.
• W2789758412 cites W2318412200 @default.
• W2789758412 cites W2334201693 @default.
• W2789758412 cites W2339763143 @default.
• W2789758412 cites W2528082263 @default.
• W2789758412 cites W2595248089 @default.
• W2789758412 cites W2779913007 @default.
• W2789758412 doi "https://doi.org/10.1016/j.cytogfr.2018.02.002" @default.
• W2789758412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29475588" @default.
• W2789758412 hasPublicationYear "2018" @default.
• W2789758412 type Work @default.
• W2789758412 sameAs 2789758412 @default.
• W2789758412 citedByCount "19" @default.
• W2789758412 countsByYear W27897584122019 @default.
• W2789758412 countsByYear W27897584122020 @default.
• W2789758412 countsByYear W27897584122021 @default.
• W2789758412 countsByYear W27897584122022 @default.
• W2789758412 countsByYear W27897584122023 @default.
• W2789758412 crossrefType "journal-article" @default.
• W2789758412 hasAuthorship W2789758412A5016243200 @default.
• W2789758412 hasAuthorship W2789758412A5069117760 @default.
• W2789758412 hasAuthorship W2789758412A5089752592 @default.
• W2789758412 hasConcept C136449434 @default.
• W2789758412 hasConcept C159047783 @default.
• W2789758412 hasConcept C193419808 @default.
• W2789758412 hasConcept C203014093 @default.
• W2789758412 hasConcept C2522874641 @default.
• W2789758412 hasConcept C2776178377 @default.
• W2789758412 hasConcept C2777995582 @default.
• W2789758412 hasConcept C2778278966 @default.
• W2789758412 hasConcept C2779341262 @default.
• W2789758412 hasConcept C86803240 @default.
• W2789758412 hasConcept C8891405 @default.
• W2789758412 hasConceptScore W2789758412C136449434 @default.
• W2789758412 hasConceptScore W2789758412C159047783 @default.
• W2789758412 hasConceptScore W2789758412C193419808 @default.
• W2789758412 hasConceptScore W2789758412C203014093 @default.
• W2789758412 hasConceptScore W2789758412C2522874641 @default.
• W2789758412 hasConceptScore W2789758412C2776178377 @default.
• W2789758412 hasConceptScore W2789758412C2777995582 @default.

• next