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- W2789760802 abstract "Chitosan is a type of carbohydrate compounds produced from waste marine products, in particular the class of shrimp, crabs and clams. Chitosan is often process into edible films and utilized for food packaging also has potential as a membrane for drug delivery system. Drug loading and drug release can be controlled by improve the characteristics of the membrane by adding crosslinker. The purpose of this research is to study the effect of addition of crosslinker to the rate of loading and release of ascorbic acid in the chitosan edible film. Na 2 SO 3 was used as crosslinker. Two grams of chitosan was dissolved into 100 ml of distilled water. Acetic acid and plasticizer were added in the solution then heated at 50°C. Na 2 SO 3 solution with mass various of Na 2 SO 3 dissolved, 01026 0.3; and 0.5 grams were added about 30 mL to make edible film. The analysis include of drug loading, drug release and tensile strength. The result showed that the loading of edible film with crosslinker 0.15 g; 0.3 g; and 0.5 g respectively were 60.98 ppm; 52.53 ppm; and 40.88 ppm, meanwhile for the release with crosslinker 0.15 g; 0.3 g; and 0.5 g respectively were 3.78 ppm; 5.72 ppm; and 5.97 ppm." @default.
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- W2789760802 date "2018-01-01" @default.
- W2789760802 modified "2023-09-26" @default.
- W2789760802 title "Effect of Na<sub>2</sub>SO<sub>3</sub> concentration to drug loading and drug release of ascorbic acid in chitosan edible film as drug delivery system membrane" @default.
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- W2789760802 doi "https://doi.org/10.1051/matecconf/201815401026" @default.
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