Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789817536> ?p ?o ?g. }
- W2789817536 abstract "Abstract Any therapy that aims at eradicating a cancerous growth will have at its core a cell death-inducing component. Here we argue that paediatric oncology presents with its unique set of considerations and problems, which—while taking the lead from oncological research experiences obtained from the adult population—need to be clinically evaluated independently. This is particularly true when considering long-term side effects. Precision medicine offers a promising new approach in therapy, but given as a monotherapy and in a limited combination, as found in an apoptosis inducer/sensitiser combination, it will most likely lead to mutation escape of the target cell population and the emergence of resistance. However, using the increasing amount of the molecular data as the basis for a complex combination therapy combining several key components such as cell death-inducing agents, kinase inhibitors and BH3 mimetics, holds great promise." @default.
- W2789817536 created "2018-03-29" @default.
- W2789817536 creator A5021490889 @default.
- W2789817536 creator A5075397312 @default.
- W2789817536 creator A5079278058 @default.
- W2789817536 creator A5080479067 @default.
- W2789817536 creator A5085608259 @default.
- W2789817536 creator A5087856756 @default.
- W2789817536 date "2018-01-25" @default.
- W2789817536 modified "2023-10-10" @default.
- W2789817536 title "Cell death-based treatment of childhood cancer" @default.
- W2789817536 cites W1481059651 @default.
- W2789817536 cites W1547601828 @default.
- W2789817536 cites W1569839307 @default.
- W2789817536 cites W1829810608 @default.
- W2789817536 cites W1864887926 @default.
- W2789817536 cites W1958519031 @default.
- W2789817536 cites W1964422747 @default.
- W2789817536 cites W1966568350 @default.
- W2789817536 cites W1967469505 @default.
- W2789817536 cites W1969665013 @default.
- W2789817536 cites W1971593855 @default.
- W2789817536 cites W1973751980 @default.
- W2789817536 cites W1977844138 @default.
- W2789817536 cites W1984229970 @default.
- W2789817536 cites W1985745999 @default.
- W2789817536 cites W1986356220 @default.
- W2789817536 cites W1993339180 @default.
- W2789817536 cites W2001675597 @default.
- W2789817536 cites W2005133500 @default.
- W2789817536 cites W2014701886 @default.
- W2789817536 cites W2016899610 @default.
- W2789817536 cites W2018905693 @default.
- W2789817536 cites W2019349530 @default.
- W2789817536 cites W2021033166 @default.
- W2789817536 cites W2032560191 @default.
- W2789817536 cites W2032647092 @default.
- W2789817536 cites W2034269086 @default.
- W2789817536 cites W2037066552 @default.
- W2789817536 cites W2040228556 @default.
- W2789817536 cites W2040931015 @default.
- W2789817536 cites W2040967802 @default.
- W2789817536 cites W2052853635 @default.
- W2789817536 cites W2054717287 @default.
- W2789817536 cites W2057497222 @default.
- W2789817536 cites W2058943435 @default.
- W2789817536 cites W2060135729 @default.
- W2789817536 cites W2065423665 @default.
- W2789817536 cites W2066861312 @default.
- W2789817536 cites W2070007455 @default.
- W2789817536 cites W2075283012 @default.
- W2789817536 cites W2075452470 @default.
- W2789817536 cites W2076870257 @default.
- W2789817536 cites W2077098920 @default.
- W2789817536 cites W2077858999 @default.
- W2789817536 cites W2080232352 @default.
- W2789817536 cites W2085921275 @default.
- W2789817536 cites W2088923689 @default.
- W2789817536 cites W2090437258 @default.
- W2789817536 cites W2094244560 @default.
- W2789817536 cites W2095970177 @default.
- W2789817536 cites W2096287682 @default.
- W2789817536 cites W2104287359 @default.
- W2789817536 cites W2109948920 @default.
- W2789817536 cites W2111118397 @default.
- W2789817536 cites W2111406583 @default.
- W2789817536 cites W2112327309 @default.
- W2789817536 cites W2112612051 @default.
- W2789817536 cites W2117692326 @default.
- W2789817536 cites W2118071133 @default.
- W2789817536 cites W2119449786 @default.
- W2789817536 cites W2119523599 @default.
- W2789817536 cites W2121302546 @default.
- W2789817536 cites W2123923858 @default.
- W2789817536 cites W2128760555 @default.
- W2789817536 cites W2129050569 @default.
- W2789817536 cites W2132954482 @default.
- W2789817536 cites W2137236379 @default.
- W2789817536 cites W2137571255 @default.
- W2789817536 cites W2141604895 @default.
- W2789817536 cites W2141872294 @default.
- W2789817536 cites W2144535782 @default.
- W2789817536 cites W2146216168 @default.
- W2789817536 cites W2149949542 @default.
- W2789817536 cites W2153716722 @default.
- W2789817536 cites W2154563173 @default.
- W2789817536 cites W2157863243 @default.
- W2789817536 cites W2158954941 @default.
- W2789817536 cites W2160811827 @default.
- W2789817536 cites W2170343590 @default.
- W2789817536 cites W2180814902 @default.
- W2789817536 cites W2210259689 @default.
- W2789817536 cites W2290293396 @default.
- W2789817536 cites W2303408208 @default.
- W2789817536 cites W2334948925 @default.
- W2789817536 cites W2490374777 @default.
- W2789817536 cites W2503515884 @default.
- W2789817536 cites W2513545035 @default.
- W2789817536 cites W2517666596 @default.
- W2789817536 cites W2520600487 @default.